Zobrazeno 1 - 7
of 7
pro vyhledávání: '"S J, Rayment"'
Autor:
V. G. Wilson, H. J. Gruss, Dashwood, J Simpson, Austin G. Acheson, S. J. Rayment, T. Eames, John H Scholefield, Y. Henry
Publikováno v:
British Journal of Pharmacology. 160:1727-1740
BACKGROUND AND PURPOSE We have investigated the distribution of α-adrenoceptors in sheep internal anal sphincter (IAS), as a model for the human tissue, and evaluated various imidazoline derivatives for potential treatment of faecal incontinence. EX
Autor:
Sandra Tribolo, Sunita Suri, Moira A. Taylor, V. G. Wilson, Paul A. Kroon, XH Liu, David A. Hughes, Paul W. Needs, S. J. Rayment
Publikováno v:
British Journal of Pharmacology. 159:566-575
Background and purpose: Quercetin is a major flavonoid that contributes to the reduced risk of cardiovascular disease associated with dietary ingestion of fruits and vegetables. We have pharmacologically characterized the effect of quercetin, and its
Publikováno v:
British Journal of Pharmacology. 150:604-612
Background and purpose: The uracil nucleotides UDP and UTP have been reported to activate P2Y2, P2Y4 and P2Y6 receptors to cause vasoconstriction. We have performed a comparative analysis of these receptors in endothelium-denuded smooth muscle from p
Publikováno v:
The FASEB Journal. 21:577-585
In this study, we have investigated the mechanism of ADP-induced relaxation of porcine coronary artery (PCA) rings. The P2Y receptor agonists ADP and ADPbetaS produced concentration-dependent relaxation of endothelium-denuded PCA smooth muscle with p
Autor:
S. J. Rayment, Austin G. Acheson, H. J. Gruss, Y. Henry, V. G. Wilson, T. Eames, Michael R. Dashwood, John H. Scholefield, J Simpson
Publikováno v:
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 26(8)
Background The role of α-adrenoceptors in promoting continence through modulation of sphincter tone has focused primarily on the effects of α1-adrenoceptors. We have used three clinically available agents, which are selective for α2-adrenoceptors,
Publikováno v:
British journal of pharmacology. 150(5)
The uracil nucleotides UDP and UTP have been reported to activate P2Y2, P2Y4 and P2Y6 receptors to cause vasoconstriction. We have performed a comparative analysis of these receptors in endothelium-denuded smooth muscle from porcine isolated coronary
Publikováno v:
The FASEB Journal. 21:1953-1953
The comments from Dieterich et al. on our recent publication in The FASEB Journal (1) is welcomed, as we have yet to determine a precise mechanism for the effects which we reported. However, their interpretation of the data glosses over some key poin