Zobrazeno 1 - 10
of 61
pro vyhledávání: '"S J, Marsh"'
Autor:
Andreas Goebel, David Brown, Victoria Thompson, Joanne M. Reilly, Backialakshmi Dharmalingam, S. J. Marsh
Publikováno v:
Experimental Neurology. 277:96-102
Complex regional pain syndrome (CRPS) is thought to have an auto-immune component. One such target recently proposed from the effects of auto-immune IgGs on Ca(2+) transients in cardiac myocytes and cell lines is the α1-adrenoceptor. We have tested
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de346ec0b92c5ad010e6559bc61ea1d0
https://doi.org/10.1016/j.expneurol.2015.12.009
https://doi.org/10.1016/j.expneurol.2015.12.009
Publikováno v:
Pflugers Archiv
Skin keratinocytes fulfil important signalling and protective functions. Immunocytochemical experiments revealed the unexpected presence of immunoreactivity for the M-type potassium channel subunit Kv7.2 in the keratinocyte layer of intact rat paw sk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc36010c620b4e9d9a950c66b04518cf
https://doi.org/10.1007/s00424-013-1276-2
https://doi.org/10.1007/s00424-013-1276-2
Publikováno v:
The Journal of Physiology. 582:917-925
M-channels are voltage-gated K+ channels that regulate the excitability of many neurons. They are composed of Kv7 (KCNQ) family subunits, usually Kv7.2 + Kv7.3. Native M-channels and expressed Kv7.2 + 7.3 channels are inhibited by stimulating Gq/11-c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df64ffadb9d91a47ff54f8767540a2e2
https://doi.org/10.1113/jphysiol.2007.132498
https://doi.org/10.1113/jphysiol.2007.132498
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 455:115-124
The open state of M(Kv7.2/7.3) potassium channels is maintained by membrane phosphatidylinositol-4,5-bisphosphate (PI(4,5)P(2)). They can be closed on stimulating receptors that induce PI(4,5)P(2) hydrolysis. In sympathetic neurons, closure induced b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5db76a3c2d157b34636e6736cd78928b
https://doi.org/10.1007/s00424-007-0259-6
https://doi.org/10.1007/s00424-007-0259-6
Autor:
S. J. Marsh, Elizabeth A. Matthews, M. Mistry, Stephen Antony Burbidge, Terry A. Brown, Anthony H. Dickenson, Gayle M. Passmore, David Brown, Martin Main, M AlQatari, A. A. Selyanko
Publikováno v:
The Journal of Neuroscience. 23:7227-7236
Neuronal hyperexcitability is a feature of epilepsy and both inflammatory and neuropathic pain. M currents [IK(M)] play a key role in regulating neuronal excitability, and mutations in neuronal KCNQ2/3 subunits, the molecular correlates of IK(M), hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::098d883d40867284acc5647c32215b2a
https://doi.org/10.1523/jneurosci.23-18-07227.2003
https://doi.org/10.1523/jneurosci.23-18-07227.2003
Publikováno v:
The Journal of Physiology. 550:83-101
Patch-clamp recording combined with indo-l measurement of free intracellular calcium concentration ([Ca2+]i) was used to determine the homeostatic systems involved in the maintenance of resting [Ca2+]I and in the clearance of Ca2+ transients followin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::661a7ed2590d7b10e105dd954b9d0b69
https://doi.org/10.1113/jphysiol.2002.035782
https://doi.org/10.1113/jphysiol.2002.035782
Publikováno v:
The Journal of Physiology. 544:29-37
M-type K(+) currents (I(K(M))) play a key role in regulating neuronal excitability. In sympathetic neurons, M-channels are thought to be composed of a heteromeric assembly of KCNQ2 and KCNQ3 K(+) channel subunits. Here, we have tried to identify the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d98491b94da0aaf5a4bfa34abd5509aa
https://doi.org/10.1113/jphysiol.2002.028571
https://doi.org/10.1113/jphysiol.2002.028571
Autor:
P Delmas, L J Drew, David Brown, S. J. Marsh, Noel J. Buckley, Romke Bron, Fe C. Abogadie, Jane E. Haley
Publikováno v:
Neuropharmacology. 42:950-957
Antisense approaches are increasingly used to dissect signaling pathways linking cell surface receptors to intracellular effectors. Here we used a recombinant adenovirus to deliver G-protein alpha(q) antisense into rat superior cervical ganglion (SCG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b167aded3c359a798a5b95b4e54ab8bb
https://doi.org/10.1016/s0028-3908(02)00044-8
https://doi.org/10.1016/s0028-3908(02)00044-8
Publikováno v:
Cell Calcium. 26:261-269
Using1999 Harcourt Publishers Ltdthe ratiometric Ca 2+ indicator, indo-1, the antigen-induced increase in intracellular Ca 2+ concentration ([Ca 2+ ] i ) was measured in individual RBL–2H3 cells which had been passively sensitized with monoclonal a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7da0ed32404c51ef6ae6258c5fcbdf26
https://doi.org/10.1054/ceca.1999.0065
https://doi.org/10.1054/ceca.1999.0065
Autor:
David Brown, S. J. Marsh, Olaf Pongs, Rudiger M. Weseloh, Jost Ludwig, Jochen Röper, Catherine E. Stansfeld
Publikováno v:
Proceedings of the National Academy of Sciences. 93:9910-9914
We have studied the properties of r-eag voltage-activated potassium channels in a stably transfected human embryonic kidney cell line. It was found that r-eag channels are rapidly and reversibly inhibited by a rise in intracellular calcium from 30 to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f12b5641212d47ffa59701df67bba3c
https://doi.org/10.1073/pnas.93.18.9910
https://doi.org/10.1073/pnas.93.18.9910