Zobrazeno 1 - 10
of 16
pro vyhledávání: '"S J, Khoury"'
Autor:
Z, Liptak, A M, Berger, M P, Sampat, A, Charil, O, Felsovalyi, B C, Healy, P, Hildenbrand, S J, Khoury, H L, Weiner, R, Bakshi, C R G, Guttmann
Publikováno v:
AJNR Am J Neuroradiol
BACKGROUND AND PURPOSE: While brain MR imaging is routinely performed, the MR imaging assessment of spinal cord pathology in multiple sclerosis (MS) is less frequent in clinical practice. The purpose of this study was to determine whether measurement
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9a6a903b2fdd831fcbeb3177e4c25387
https://pubmed.ncbi.nlm.nih.gov/18556361
https://pubmed.ncbi.nlm.nih.gov/18556361
Publikováno v:
Ernst Schering Research Foundation workshop. (53)
Neural stem and progenitor cells express a variety of receptors that enable them to sense and react to signals emanating from physiological and pathophysiological conditions in the brain as well as elsewhere in the body. Many of these receptors and w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::37a161ca9f42b94469a9d2a122cba3df
https://pubmed.ncbi.nlm.nih.gov/16315610
https://pubmed.ncbi.nlm.nih.gov/16315610
Publikováno v:
The Journal of clinical investigation. 108(5)
Experimental autoimmune encephalomyelitis (EAE) is mediated by myelin-specific CD4(+) T cells secreting Th1 cytokines, while recovery from disease is associated with expression of Th2 cytokines. Investigations into the role of individual cytokines in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::604265c5650007be7327e0e7f0e3c9ba
https://pubmed.ncbi.nlm.nih.gov/11544280
https://pubmed.ncbi.nlm.nih.gov/11544280
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 162(2)
Injection of Ag into the thymus of adult animals induces specific systemic tolerance. The mechanisms of acquired thymic tolerance include anergy and the deletion of Ag-specific T cells. Here, we report that anergy to nominal Ag induced via acquired t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b47b1c6e73ef7d683afba8be9f745a56
https://pubmed.ncbi.nlm.nih.gov/9916696
https://pubmed.ncbi.nlm.nih.gov/9916696
Autor:
A M, Waaga, A, Chandraker, M, Spadafora-Ferreira, A R, Iyengar, S J, Khoury, C B, Carpenter, M H, Sayegh
Publikováno v:
Transplantation. 65(7)
Recent evidence indicates that T cells primed via the indirect pathway of allorecognition play an important role in allograft rejection, although the effector mechanisms remain unknown. The purpose of this study was to characterize and study the in v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b375512dcb58e397ef2d69207df6cd8d
https://pubmed.ncbi.nlm.nih.gov/9565089
https://pubmed.ncbi.nlm.nih.gov/9565089
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 160(3)
Intrathymic injection of Ag induces Ag-specific tolerance in several clinically relevant experimental autoimmune and transplantation models. However, the exact mechanisms of acquired thymic tolerance in vivo remain unclear. We investigated the mechan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e6fd16c78bde7f78c2bb04a28916eeca
https://pubmed.ncbi.nlm.nih.gov/9570573
https://pubmed.ncbi.nlm.nih.gov/9570573
Autor:
L, Gallon, A, Chandraker, S, Issazadeh, R, Peach, P S, Linsley, L A, Turka, M H, Sayegh, S J, Khoury
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 159(9)
Blocking the CD28-B7 T cell costimulatory activation pathway protects animals from developing experimental autoimmune encephalomyelitis (EAE). In the mouse EAE model, selective blockade of B7-1 by specific mAbs has been shown to protect animals from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::792bf89fb08b8f316c368ab0ea998dce
https://pubmed.ncbi.nlm.nih.gov/9379015
https://pubmed.ncbi.nlm.nih.gov/9379015
Autor:
S J, Khoury, L, Gallon, R R, Verburg, A, Chandraker, R, Peach, P S, Linsley, L A, Turka, W W, Hancock, M H, Sayegh
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 157(8)
We used a novel approach to study the role of CD28-B7 T cell costimulatory blockade in experimental autoimmune encephalomyelitis (EAE) in the Lewis rat model. APCs were incubated in vitro with CTLA4Ig and the encephalitogenic peptide p71-90 of myelin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6ae73f0e1ae49c0e0d14a28d04c7b94a
https://pubmed.ncbi.nlm.nih.gov/8871673
https://pubmed.ncbi.nlm.nih.gov/8871673
Publikováno v:
Transplantation. 62(6)
Recent animal studies suggest that indirect T-cell recognition of alloantigen plays an important role in allograft rejection and tolerance. In this study, we generated T cell clones from Lewis (LEW, RT1(l)) rat lymph node cells that had been primed i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7026d446ee5edb386ddf7978579e82fd
https://pubmed.ncbi.nlm.nih.gov/8824464
https://pubmed.ncbi.nlm.nih.gov/8824464
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 155(10)
We studied the contribution of the CD28-B7 costimulatory T cell activation pathway to the pathogenesis of experimental autoimmune encephalomyelitis in the Lewis rat model. Systemic administration of CTLA4Ig suppressed clinical disease and was effecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fe25d8af5de7ced23f8a1863573d62a9
https://pubmed.ncbi.nlm.nih.gov/7594447
https://pubmed.ncbi.nlm.nih.gov/7594447