Zobrazeno 1 - 5
of 5
pro vyhledávání: '"S J, Iturria"'
Autor:
S. J. ITURRIA, J. BLANGERO
Publikováno v:
Annals of Human Genetics. 64:349-362
Autor:
C. S. Ernest, D. R. Lachno, John T. Brandt, Kenneth J. Winters, Christopher D. Payne, Sandra L Close, Nagy A. Farid, Daniel E. Salazar, S. J. Iturria
Publikováno v:
Journal of thrombosis and haemostasis : JTH. 5(12)
Summary. Background: Thienopyridines are metabolized to active metabolites that irreversibly inhibit the platelet P2Y12 adenosine diphosphate receptor. The pharmacodynamic response to clopidogrel is more variable than the response to prasugrel, but t
Autor:
B D, Mitchell, S A, Cole, R L, Bauer, S J, Iturria, E A, Rodriguez, J, Blangero, J W, MacCluer, J E, Hixson
Publikováno v:
The Journal of clinical endocrinology and metabolism. 85(4)
Osteocalcin (OC) is an important constituent of bone that is synthesized by osteoblasts. Serum levels of OC have been used as a biochemical marker of bone turnover. To identify the genes influencing variation in serum OC levels, we conducted a genome
Publikováno v:
Genetic epidemiology. 17
We propose a constrained permutation test that assesses the significance of an observed quantitative trait locus effect against a background of genetic and environmental variation. Permutations of phenotypes are not selected at random, but rather are
Publikováno v:
Genetic epidemiology. 17
The traditional likelihood-based approach to hypothesis testing may not be an optimal strategy for evaluating oligogenic models of inheritance. Under oligogenic inheritance the number of possible multilocus models can become very large; there may be