Zobrazeno 1 - 10
of 61
pro vyhledávání: '"S J, Gatley"'
Publikováno v:
Nicotine & Tobacco Research. 1:127-132
Although the effects of nicotine in the brains of laboratory animals have been investigated extensively, very little is known about its effects in the human brain. With positron emission tomography (PET), a non-invasive imaging technology that allows
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be5eae4e7d62a89f75ace8c2306fda07
https://doi.org/10.1080/14622299050011941
https://doi.org/10.1080/14622299050011941
Autor:
N. D. Volkow, G. -J. Wang, S. J. Gatley, J. S. Fowler, Y. -S. Ding, J. Logan, R. Hitzemann, B. Angrist, J. Lieberman
Publikováno v:
Psychopharmacology. 123:26-33
Positron emission tomography was used to compare the pharmacokinetics of [11C]methylphenidate in the human brain with the temporal course of the subjective and cardiovascular effects observed after intravenous methylphenidate (0.5 mg/kg). Four subjec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30ba746623d52ed3e5c06ec78417ec8e
https://doi.org/10.1007/bf02246277
https://doi.org/10.1007/bf02246277
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 31:219-225
An 123I labeled cocaine analog, 4′-[123I]iodococaine, has been prepared by oxidative destannylation of the tributyltin analog and shown to interact with cocaine binding sites in rat brain striatal membranes. It may thus be a suitable SPECT radiotra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c5709ebdd1efaa983cc279bad3bf72a
https://doi.org/10.1002/jlcr.2580310307
https://doi.org/10.1002/jlcr.2580310307
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 29:393-403
Convenient preparations of 80mBr and 123I-labeled 5-halodeoxyuridines, required for basic investigations of Auger electron radiotoxicity, are described. These radioactive thymidine analogs were synthesized from deoxyuridine, radiohalide and N-chloros
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a781a3d1ed0d4320025c799e01a0405
https://doi.org/10.1002/jlcr.2580290405
https://doi.org/10.1002/jlcr.2580290405
Publikováno v:
Handbook of experimental pharmacology. (168)
This review covers two major strategies for imaging of the brain cannabinoid system: autoradiography and in vivo neuroimaging. Cannabinoid receptors can be imaged directly with autoradiography in brain slices using radiolabeled cannabinoid receptor l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f9b010b749d6a94da6ae6a018b9f6e6a
https://pubmed.ncbi.nlm.nih.gov/16596783
https://pubmed.ncbi.nlm.nih.gov/16596783
Publikováno v:
Handbook of Experimental Pharmacology ISBN: 354022565X
This review covers two major strategies for imaging of the brain cannabinoid system: autoradiography and in vivo neuroimaging. Cannabinoid receptors can be imaged directly with autoradiography in brain slices using radiolabeled cannabinoid receptor l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7eb9ec0887d4eff79f4d9b4a26789f35
https://doi.org/10.1007/3-540-26573-2_14
https://doi.org/10.1007/3-540-26573-2_14
Autor:
J S, Fowler, J, Logan, Y S, Ding, D, Franceschi, G J, Wang, N D, Volkow, N, Pappas, D, Schlyer, S J, Gatley, D, Alexoff, C, Felder, A, Biegon, W, Zhu
Publikováno v:
Journal of neurochemistry. 79(5)
Clorgyline is an irreversible inhibitor of monoamine oxidase (MAO A) which has been labeled with carbon-11 (C-11) and used to measure human brain MAO A with positron emission tomography (PET). In this study we compared [11C]clorgyline and deuterium-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ac78f8cf6c41e9770601286e04a6dfce
https://pubmed.ncbi.nlm.nih.gov/11739617
https://pubmed.ncbi.nlm.nih.gov/11739617
Autor:
N D, Volkow, G J, Wang, J S, Fowler, W D, Rooney, C A, Felder, J H, Lee, D, Franceschi, L, Maynard, D J, Schlyer, J W, Pan, S J, Gatley, C S, Springer
Publikováno v:
Magnetic resonance in medicine. 44(5)
MRI is a major tool for mapping brain function; thus it is important to assess potential effects on brain neuronal activity attributable to the requisite static magnetic field. This study used positron emission tomography (PET) and (18)F-deoxyglucose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8e4de9b4326e5f4fee92a389bca68513
https://pubmed.ncbi.nlm.nih.gov/11064404
https://pubmed.ncbi.nlm.nih.gov/11064404
Publikováno v:
Synapse (New York, N.Y.). 38(4)
PET and SPECT studies have documented that D2 radioligands of moderate affinity, but not radioligands of high affinity, are sensitive to pharmacological challenges that alter synaptic dopamine levels. The objective of this work was to determine wheth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f0801139ec6309ce4464592430e2a3a5
https://pubmed.ncbi.nlm.nih.gov/11044896
https://pubmed.ncbi.nlm.nih.gov/11044896
Publikováno v:
Synapse (New York, N.Y.). 38(4)
The goals of this study were to examine the relationship between intravenous doses of the cannabinoid CB1 receptor antagonist AM281 (N-(morpholin-4-yl)-5-(4-iodophenyl)-1-(2, 4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide) and the degree of occ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::15a58e354e44d1acf1b48449449d7e34
https://pubmed.ncbi.nlm.nih.gov/11044895
https://pubmed.ncbi.nlm.nih.gov/11044895