Zobrazeno 1 - 10
of 40
pro vyhledávání: '"S J, DeArmond"'
Autor:
Kara Weisiger, Seymour Packman, Nathan M. Bass, S. J. DeArmond, Charles L. Hoppel, D. Horoupian, Gregory M. Enns, Susan Schelley
Publikováno v:
Clinical Genetics. 68:337-348
Variation in the size and relative proportion of type 1 and type 2 muscle fibers can occur in a number of conditions, including structural myopathies, neuropathies, and various syndromes. In most cases, the pathogenesis of such fiber type changes is
Autor:
S J, Dearmond
Publikováno v:
Methods in molecular medicine. 59
A basic principle of microbiology that applies to all conventional infectious pathogens is that the disease phenotype is a function of both the infecting agent and the host's response to it. All evidence indicates that this principle is also true for
Publikováno v:
Annals of the Rheumatic Diseases. 51:1152-1156
The case is reported of a patient with central nervous system systemic lupus erythematosus (SLE) with features of progressive multifocal leucoencephalopathy (PML) seen clinically and by magnetic resonance imaging. A brain biopsy sample showed microin
Publikováno v:
Neurology. 71(18)
Objective: To define the clinicopathologic, genetic, and pathogenic prion protein (PrP Sc ) characteristics associated with a novel mutation of the prion protein gene ( PRNP ). Methods: The coding segment of PRNP from the proband and family members w
Autor:
G M, Enns, C L, Hoppel, S J, DeArmond, S, Schelley, N, Bass, K, Weisiger, D, Horoupian, S, Packman
Publikováno v:
Clinical genetics. 68(4)
Variation in the size and relative proportion of type 1 and type 2 muscle fibers can occur in a number of conditions, including structural myopathies, neuropathies, and various syndromes. In most cases, the pathogenesis of such fiber type changes is
Publikováno v:
Archives of virology. Supplementum. (16)
There is growing concern that bovine spongiform encephalopathy (BSE) may have passed from cattle to humans, resulting in approximately 70 cases of an atypical, variant CJD (vCJD) in teenagers and young adults. We report here that transgenic (Tg) mice
Publikováno v:
Brain research. 874(2)
The goal was to test whether all neurons are equally susceptible to degeneration in response to PrP(Sc) scrapie infection. We tested this by immunogold GABA labeling. Our ultrastructural results indicates that GABAergic neurons are less vulnerable th
Publikováno v:
Musclenerve. 22(8)
A 59-year-old man with severe neck extensor weakness had findings diagnostic of nemaline myopathy on muscle biopsy. Review of the literature shows that dropped head occurs in nearly half of the patients with adult-onset nemaline myopathy. Other leadi
Autor:
N, Nishida, P, Tremblay, T, Sugimoto, K, Shigematsu, S, Shirabe, C, Petromilli, S P, Erpel, R, Nakaoke, R, Atarashi, T, Houtani, M, Torchia, S, Sakaguchi, S J, DeArmond, S B, Prusiner, S, Katamine
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 79(6)
Disruption of both alleles of the prion protein gene, Prnp, renders mice resistant to prions; in a Prnp o/o line reported by some of us, mice progressively developed ataxia and Purkinje cell loss. Here we report torpedo-like axonal swellings associat
Autor:
T, Hökfelt, C, Broberger, X, Zhang, M, Diez, J, Kopp, Z, Xu, M, Landry, L, Bao, M, Schalling, J, Koistinaho, S J, DeArmond, S, Prusiner, J, Gong, J H, Walsh
Publikováno v:
Brain research. Brain research reviews. 26(2-3)
Using immunohistochemical and in situ hybridization methodologies the localization of neuropeptide tyrosine (NPY) and two of its receptors, the Y1- and the Y2-receptor (R), has been analysed in various tissues in normal animals and animals subjected