Zobrazeno 1 - 10
of 44
pro vyhledávání: '"S J, Czuczwar"'
Publikováno v:
Polish journal of veterinary sciences. 24(2)
Organophosphate (OP) pesticides are commonly known for their neurotoxicity. In the current experiments, two OPs used agriculturally, chlorpyrifos and dimethoate, were separately adminis- tered with centrally acting caffeine that is known to affect th
Publikováno v:
Acta Chromatographica. 29:219-234
Three independent reversed phase high-performance liquid chromatography (HPLC) procedures with diode array detection (DAD) for the analysis of carbamazepine (CBZ), topiramate (TPM), and valproic acid (VPA) have been developed in order to determine dr
Autor:
Grzegorz Sobieszek, Kinga K. Borowicz, Philip N. Patsalos, Jarogniew J. Luszczki, S. J. Czuczwar, Neville Ratnaraj
Publikováno v:
European Neuropsychopharmacology. 17:265-272
Despite the major advances in antiepileptic drug (AED) therapeutics, about one third of patients with epilepsy still do not have adequate seizure control with currently available AEDs when prescribed as monotherapy. Typically, in this setting polythe
Autor:
Piotr Gawlik, Katarzyna Czuczwar, G. Sawiniec-Pozniak, Jarogniew J. Luszczki, S. J. Czuczwar, Mirosław Czuczwar
Publikováno v:
Journal of Neural Transmission. 113:1157-1168
The effects of 7-nitroindazole (7NI, a preferential neuronal nitric oxide synthase inhibitor) on the anticonvulsant activity of four second-generation antiepileptic drugs (AEDs: felbamate [FBM], lamotrigine [LTG], oxcarbazepine [OXC] and topiramate [
Publikováno v:
European Neuropsychopharmacology. 14:163-172
The aim of this study was the isobolographic evaluation of interactions between three non-barbiturate intravenous anesthetics and conventional antiepileptic drugs in the maximal electroshock-induced seizures in mice. Electroconvulsions were produced
Publikováno v:
Journal of Neural Transmission. 107:1117-1126
The interaction of 7-nitroindazole (7-NI), a nitric oxide synthase (NOS) inhibitor, with the protective activity of conventional antiepileptics against pentylenetetrazol (PTZ)-induced seizures was tested in mice. Alone, 7-nitroindazole (up to 50 mg/k
Autor:
S J Czuczwar, Z. Kleinrok, G Ossowska, Rafal M. Kaminski, M Kozicka, M Gasior, T. Pietrasiewicz
Publikováno v:
Molecular and Chemical Neuropathology. 33:149-162
Excitatory amino acids participate in the generation of seizure activity. Consequently, the effects of GYKI 52466 [1-(4-aminophenyl)-4-methoxy-7,8-methylenedioxy-5H-2,3-benzodiazepine hydrochloride], an antagonist of glutamate-mediated events, on the
Publikováno v:
Pharmacology Biochemistry and Behavior. 54:639-644
The anticonvulsant activities of intraperitoneally (IP) given carbamazepine (CBZ) or diphenylhydantoin (DPH), expressed as their respective ED50 values in mg/kg, were assessed after caffeine (CAFF) treatment against maximal electroshock-induced seizu
Publikováno v:
Journal of neural transmission (Vienna, Austria : 1996). 114(12)
Accumulating evidence indicates that aminophylline [theophylline(2) x ethylenediamine] markedly attenuates the anticonvulsant action of conventional antiepileptic drugs in experimental animal models of epilepsy and evokes severe seizure activity in p
Publikováno v:
Journal of neural transmission (Vienna, Austria : 1996). 115(5)
This study evaluated the interactions between tiagabine (TGB) and three conventional antiepileptic drugs (AEDs): valproate (VPA), carbamazepine (CBZ), and phenobarbital (PB) in amygdala-kindled rats, a reliable model of complex partial seizures in hu