Výsledky vyhledávání - "S J, Cleland"

AMP-activated protein kinase is activated in adipose tissue of individuals with type 2 diabetes treated with metformin: a randomised glycaemia-controlled crossover study

Autor: Ian P. Salt, Michael Small, S. J. Cleland, Naveed Sattar, G. C. Jones, Pamela J. Logan, James G. Boyle, John M. C. Connell

Publikováno v: Diabetologia. 54:1799-1809

The hypoglycaemic actions of metformin have been proposed to be mediated by hepatic AMP-activated protein kinase (AMPK). As the effects of metformin and the role of AMPK in adipose tissue remain poorly characterised, we examined the effect of metform

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be582f41af46bce60081248a093be295
https://doi.org/10.1007/s00125-011-2126-4

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Effects of low-dose continuous combined hormone replacement therapy on glucose homeostasis and markers of cardiovascular risk in women with type 2 diabetes

Autor: Michael Small, Mary Ann Lumsden, S. J. Cleland, J. M. C. Connell, T. Hilditch, A Kernohan, John R. Petrie, Naveed Sattar

Publikováno v: Clinical Endocrinology. 66:27-34

Background: Low-dose hormone replacement therapy (HRT) has attracted interest for the treatment of postmenopausal symptoms in diabetes because of concerns about increased risk of coronary heart disease (CHD) and stroke with conventional HRT containin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::68a5173c250b64500d682735ccd9c39c
https://doi.org/10.1111/j.1365-2265.2006.02679.x

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Higher carotid-radial pulse wave velocity in healthy offspring of patients with Type 2 diabetes

Autor: Roland W. McCallum, John R. Petrie, Michael Small, John M. C. Connell, O. D. McEleavy, Naveed Sattar, S. J. Cleland

Publikováno v: Diabetic Medicine. 21:262-266

Aims To determine whether carotid-radial pulse wave velocity (crPWV), a simple non-invasive measurement of muscular artery structure and function, is increased in offspring of patients with Type 2 diabetes compared with well-matched controls with no

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e1e228e1115e279dddb9e32e6bf351ba
https://doi.org/10.1111/j.1464-5491.2004.01127.x

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Insulin resistance in type 1 diabetes: what is ‘double diabetes’ and what are the risks?

Autor: Helen M. Colhoun, S. J. Cleland, Bob Fisher, John R. Petrie, Naveed Sattar

Publikováno v: Diabetologia

In this review, we explore the concept of ‘double diabetes’, a combination of type 1 diabetes with features of insulin resistance and type 2 diabetes. After considering whether double diabetes is a useful concept, we discuss potential mechanisms

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::953e587688ad36b7d6d38dc621ab2a51
https://eprints.gla.ac.uk/82661/2/82661.pdf

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Effects of low-dose continuous combined hormone replacement therapy on glucose homeostasis and markers of cardiovascular risk in women with type 2 diabetes

Autor: A F B, Kernohan, N, Sattar, T, Hilditch, S J, Cleland, M, Small, M A, Lumsden, J M C, Connell, J R, Petrie

Publikováno v: Clinical endocrinology. 66(1)

Low-dose hormone replacement therapy (HRT) has attracted interest for the treatment of postmenopausal symptoms in diabetes because of concerns about increased risk of coronary heart disease (CHD) and stroke with conventional HRT containing conjugated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::960dc02759a42d64e7fa6f48b19a8449
https://pubmed.ncbi.nlm.nih.gov/17201798

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Blunted response to systemic nitric oxide synthase inhibition in the cerebral circulation of patients with Type 2 diabetes

Autor: Jmc Connell, M. Alem, Kennedy R. Lees, Fozia S Nazir, Michael Small, Matthew Walters, S. J. Cleland

Publikováno v: Diabetic medicine : a journal of the British Diabetic Association. 23(4)

Aims Diabetes is a major risk factor for stroke, but the mechanisms that impart the excess risk are unclear. Endothelial dysfunction, which has been demonstrated in the coronary and peripheral vasculature of diabetic patients, is an important early m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09300b4bf83c75d5d2d10e1f21cb5a01
https://pubmed.ncbi.nlm.nih.gov/16620268

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Effects of low-dose continuous combined HRT on vascular function in women with type 2 diabetes

Autor: Mary Ann Lumsden, Angela Spiers, Naveed Sattar, Michael Small, Chris Hillier, S. J. Cleland, John R. Petrie, Andrew Fb Kernohan, John M. C. Connell

Publikováno v: Diabetesvascular disease research. 1(2)

Background Improvement in vascular endothelial function is widely cited as a beneficial effect of hormone replacement therapy (HRT). Women with type 2 diabetes (T2DM) are at increased cardiovascular risk and have impaired endothelial function. Any be

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53ffe3a9d4ca2ebff8004afaaf6cb993
https://pubmed.ncbi.nlm.nih.gov/16302646

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Low grade inflammation is notably suppressed by conventional anti-inflammatory treatment: a randomised crossover trial

Autor: Naveed Sattar, Colin Perry, John R. Petrie, Jmc Connell, S. J. Cleland

Circulating concentrations of C reactive protein (CRP), a hepatic derived inflammatory marker that is secreted in response to specific cytokines, have been shown to predict the risk of coronary heart disease (CHD) and diabetes in large epidemiologica

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69c13098d961e1a1b579db91d690ffb2
https://europepmc.org/articles/PMC1768325/

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