CLIN-RADIATION THERAPY

Autor: W.-S. Yoon, J.-T. Kim, Y.-M. Han, D.-S. Chung, Y.-S. Park, K. J. Lizarraga, M. Allen-Auerbach, A. A. De Salles, W. H. Yong, W. Chen, M. I. Ruge, P. Kickingereder, T. Simon, H. Treuer, V. Sturm, P. R. D'Alessandro, J. Jarrett, S. A. Walling, I. G. Fleetwood, T. G. Kim, D. H. Lim, S. L. McGovern, D. Grosshans, M. F. McAleer, M. Chintagumpala, S. Khatua, T. Vats, A. Mahajan, P. D. Beauchesne, G. Faure, G. Noel, T. Schmitt, L. Martin, E. Jadaud, C. Carnin, A. Astradsson, P. M. a. Rosenschold, A. K. W. Lund, U. Feldt-Rasmussen, H. Roed, M. Juhler, N. Kumar, R. Kumar, S. C. Sharma, K. K. Mukherjee, N. Khandelwal, P. K. Gupta, A. Bansal, R. Kapoor, S. Ghosal, C. L. Barney, A. P. Brown, M. C. Lowe, D. R. Grosshans, J. F. de Groot, V. Puduvalli, M. R. Gilbert, T. S. Vats, P. D. Brown, B. E. Pollock, S. L. Stafford, M. J. Link, Y. I. Garces, R. L. Foote, S. Ryu, E. Y. Kim, R. Yechieli, J. K. Kim, T. Mikkelsen, S. Kalkanis, J. Rock, G. K. Prithviraj, P. Oppelt, L. Arfons, K. C. Cuneo, J. Vredenburgh, A. Desjardins, K. Peters, J. Sampson, Z. Chang, J. Kirkpatrick, S. K. Nath, A. D. Sheridan, P. J. Rauch, J. N. Contessa, J. B. Yu, J. P. Knisely, F. J. Minja, A. O. Vortmeyer, V. L. Chiang, M. Koto, A. Hasegawa, R. Takagi, G. Sasahara, H. Ikawa, T. Kamada, Y. Iwadate, M. Matsutani, A. A. Kanner, G. Sela, E. Gez, D. Matceyevsky, N. Strauss, B. W. Corn, D. G. Brachman, K. A. Smith, P. Nakaji, S. Sorensen, K. J. Redmond, E. M. Mahone, L. Kleinberg, S. Terezakis, T. McNutt, H. Agbahiwe, K. Cohen, M. Lim, M. Wharam, A. Horska, B. Amendola, A. Wolf, S. Coy, L. Blach, F. Mesfin, D. Suki, G. Rao, V. A. R. Palkonda, N. More, P. Ganesan, R. Kesavan, M. Shunmugavel, T. Kasirajan, V. R. Maram, S. Kakkar, P. Upadhyay, S. Das, S. Nigudgi, J. S. Katz, M. Ghaly, M. Schulder, R. B. Taylor, P. E. Schaner, A. F. Dragovic, J. M. Markert, B. L. Guthrie, M. C. Dobelbower, S. A. Spencer, J. B. Fiveash, L. Chen, H. Guerrero-Cazares, E. Ford, A. Quinones-Hinojosa, K. Redmond, A. G. Wernicke, K. C. Chao, D. Nori, B. Parashar, M. Yondorf, J. A. Boockvar, S. Pannullo, P. Stieg, T. H. Schwartz, J. E. Leeman, D. A. Clump, J. C. Flickinger, S. A. Burton, A. H. Mintz, D. E. Heron, S. H. O'Neil, K. Wong, C. Buranahirun, B. Gonzalez-Morkos, R. J. Brown, A. Hamilton, J. Malvar, R. Sposto, G. Dhall, J. Finlay, A. Olch, K. Reddy, D. Damek, L. Gaspar, D. Ney, B. Kavanagh, A. Waziri, K. Lillehei, K. Stuhr, C. Chen, K. Kalakota, O. Offor, R. Patel, R. Dess, A. Schumacher, I. Helenowski, M. Marymont, P. Sperduto, S. J. Chmura, M. Mehta, G. Zadeh, W. Shi, H. Liu, M. Studenski, L. Fu, C. Peng, V. Gunn, S. Rudoler, C. Farrell, D. Andrews, J. Chu, J. Turian, J. W. Rooney, J. A. B. Ramiscal, N. N. Laack, K. Shah, M. Surucu, E. Melian, D. Anderson, V. Prabhu, T. Origitano, A. Sethi, B. Emami

Publikováno v: Neuro-Oncology. 14:vi133-vi141

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7afa450dbc9000b4f6f23d65107b36bd
https://doi.org/10.1093/neuonc/nos238

In vitro and in vivo activity of protein kinase C inhibitor chelerythrine chloride induces tumor cell toxicity and growth delay in vivo

Autor: S J, Chmura, M E, Dolan, A, Cha, H J, Mauceri, D W, Kufe, R R, Weichselbaum

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 6(2)

Although clonogenic or divisional death is the main mechanism by which DNA-damaging agents demonstrate antitumor activity, recent data indicate that strategies specifically designed to trigger apoptosis may also prove to be useful antitumor agents. P

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d1937af2d0b9f760c8dd73232660d271
https://pubmed.ncbi.nlm.nih.gov/10690561

Activated calphostin C cytotoxicity is independent of p53 status and in vivo metastatic potential

Autor: Z, Dubauskas, T P, Beck, S J, Chmura, D A, Kovar, M M, Kadkhodaian, M, Shrivastav, T, Chung, W M, Stadler, C W, Rinker-Schaeffer

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 4(10)

The development of novel therapeutic agents to modulate programmed cell death independent of genetic background or malignant potential is a primary goal of modern cancer therapy. In this report, the light activation- and concentration-dependent cytot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4c2ee1c7ef67081977d0c176629bf3d1
https://pubmed.ncbi.nlm.nih.gov/9796970

Decreasing the apoptotic threshold of tumor cells through protein kinase C inhibition and sphingomyelinase activation increases tumor killing by ionizing radiation

Autor: S J, Chmura, H J, Mauceri, S, Advani, R, Heimann, M A, Beckett, E, Nodzenski, J, Quintans, D W, Kufe, R R, Weichselbaum

Publikováno v: Cancer research. 57(19)

Approximately 30% of cancer deaths result from the failure to control local and regional tumors. The goal of radiotherapy is to maximize local and regional tumor cell killing while minimizing normal tissue destruction. Attempts to enhance radiation-m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::42dba384eac7b4301a76a68ee6c29cae
https://pubmed.ncbi.nlm.nih.gov/9331096

Protein kinase C inhibition induces apoptosis and ceramide production through activation of a neutral sphingomyelinase

Autor: S J, Chmura, E, Nodzenski, R R, Weichselbaum, J, Quintans

Publikováno v: Cancer research. 56(12)

We report that WEHI-231 undergo apoptosis following exposure to the protein kinase C inhibitors chelerythrine chloride and calphostin C. Following the addition of chelerythrine or calphostin C to WEHI-231 cells, ceramide production increased over bas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a390aed8a8b75192c3300d08432547df
https://pubmed.ncbi.nlm.nih.gov/8665499