Zobrazeno 1 - 7
of 7
pro vyhledávání: '"S J, Caradonna"'
Autor:
R D, Ladner, F J, Lynch, S, Groshen, Y P, Xiong, A, Sherrod, S J, Caradonna, J, Stoehlmacher, H J, Lenz
Publikováno v:
Cancer research. 60(13)
Aberrant dUTP metabolism plays a significant role in the underlying molecular mechanisms of cell killing mediated by inhibitors of thymidylate biosynthesis. dUTP nucleotidohydrolase (dUTPase) is the key regulator of dUTP pools, and significant eviden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f0d1a1a12a13a7858a32b354e79657c2
https://pubmed.ncbi.nlm.nih.gov/10910061
https://pubmed.ncbi.nlm.nih.gov/10910061
Autor:
R D, Ladner, S J, Caradonna
Publikováno v:
The Journal of biological chemistry. 272(30)
We have previously identified distinct nuclear and mitochondrial isoforms of dUTPase in human cells, reporting the cDNA sequence of the nuclear isoform (DUT-N). We now report a cDNA corresponding to the mitochondrial isoform (DUT-M). The DUT-M cDNA c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4bb7b3c448ae54e8a1caa4c8df316339
https://pubmed.ncbi.nlm.nih.gov/9228092
https://pubmed.ncbi.nlm.nih.gov/9228092
Autor:
D M Adamkiewicz, S J Caradonna
Publikováno v:
Journal of Biological Chemistry. 259:5459-5464
Deoxyuridine triphosphate nucleotidohydrolase (dUTPase) (EC 3.6.1.23) derived from HeLa S3 cells has been purified to near homogeneity as judged by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. The purified enzyme has a specific activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::000f6cf0e6a158efec72106c7630cf43
https://doi.org/10.1016/s0021-9258(18)91033-1
https://doi.org/10.1016/s0021-9258(18)91033-1
Autor:
S J, Caradonna, D M, Adamkiewicz
Publikováno v:
The Journal of biological chemistry. 259(9)
Deoxyuridine triphosphate nucleotidohydrolase (dUTPase) (EC 3.6.1.23) derived from HeLa S3 cells has been purified to near homogeneity as judged by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. The purified enzyme has a specific activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7c3b5573ff3efa4f1c5e04d77ad703e8
https://pubmed.ncbi.nlm.nih.gov/6143756
https://pubmed.ncbi.nlm.nih.gov/6143756
Autor:
S J, Caradonna, Y C, Cheng
Publikováno v:
The Journal of biological chemistry. 255(6)
The enzyme uracil DNA-glycosylase has been purified from blast cells of patients with acute myelocytic leukemia. A 1000-fold purification has been achieved and the enzyme appears highly enriched for the uracil glycosylase activity as judged by sodium
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dc9a99a5421d35a1fa37118c31a16a61
https://pubmed.ncbi.nlm.nih.gov/6766936
https://pubmed.ncbi.nlm.nih.gov/6766936
Autor:
S J, Caradonna, Y C, Cheng
Publikováno v:
Molecular pharmacology. 18(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a6b767b29641644e1a97144cd2f75423
https://pubmed.ncbi.nlm.nih.gov/6110169
https://pubmed.ncbi.nlm.nih.gov/6110169
Autor:
S J, Caradonna, Y C, Cheng
Publikováno v:
The Journal of biological chemistry. 256(19)
HeLa BU cells infected with either the type 1 or the type 2 forms of herpes simplex virus show an increase in the activities of uracil-DNA glycosylase and dUTP nucleotidohydrolase. Under optimal conditions, uracil-DNA glycosylase activity increases a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e9eb5d35bce1c66cb92253ee408d5b09
https://pubmed.ncbi.nlm.nih.gov/6115860
https://pubmed.ncbi.nlm.nih.gov/6115860