Zobrazeno 1 - 10 of 17 pro vyhledávání: '"S J, Brister"'
2
Selective and sustained inhibition of surface-bound thrombin activity by intimatan/heparin cofactor II and its relevance to assessing systemic anticoagulation in vivo, ex vivo and in vitro
Autor: M R, Buchanan, G A, Maclean, S J, Brister
Publikováno v: Thrombosis and haemostasis. 86(3)
We compare the relative activities of surface-bound and fluid-phase thrombin and their inhibition by heparin and Intimatan, a novel heparin cofactor II (HCII) agonist. In vitro, we compared the observed amidolytic activities of fluid-phase and surfac
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bf4d2345116e4ea8e1c5e3944f932397
https://pubmed.ncbi.nlm.nih.gov/11583326
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3
Results of the BRAT study--a pilot study investigating the possible significance of ASA nonresponsiveness on the benefits and risks of ASA on thrombosis in patients undergoing coronary artery bypass surgery
Autor: M R, Buchanan, L, Schwartz, M, Bourassa, S J, Brister, C M, Peniston
Publikováno v: The Canadian journal of cardiology. 16(11)
Several studies suggest that acetylsalicylic acid (ASA) is less effective in preventing thrombotic events in ASA nonresponder patients. If so, the thrombotic event rate in ASA nonresponders should be higher than in ASA responders.To conduct a prospec
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1074257fec65818a77a68e1772e88a44
https://pubmed.ncbi.nlm.nih.gov/11109035
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4
A rationale for targeting antithrombotic therapy at the vessel wall: improved antithrombotic effect and decreased risk of bleeding
Autor: M R, Buchanan, S J, Brister
Publikováno v: Wiener klinische Wochenschrift. 111(3)
Intimal hyperplasia after percutaneous transluminal coronary angioplasty (PTCA) or vascular surgical procedures remains a significant problem despite current antithrombotic therapy. The use of the current antithrombotic drugs, namely heparin + chroni
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::adb49a6087cde01ec002ef6f86b468fa
https://pubmed.ncbi.nlm.nih.gov/10093889
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5
Inhibition of chronic vessel wall intimal hyperplasia following acute anticoagulant treatment: relative effects of heparin and dermatan sulphate
Autor: M R, Buchanan, S J, Brister
Publikováno v: Thrombosis research. 91(4)
Surface-bound thrombin which contributes to vessel wall hyperplasia, is resistant to inhibition by heparin/antithrombin III (/ATIII) but not to inhibition by dermatan sulphate/heparin cofactor II (/HCII). To determine the effects of heparin and derma
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1ad22fc85615ae8c3e5f96c19b66d7af
https://pubmed.ncbi.nlm.nih.gov/9736418
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9
Individual variation in the effects of ASA on platelet function: implications for the use of ASA clinically
Autor: M R, Buchanan, S J, Brister
Publikováno v: The Canadian journal of cardiology. 11(3)
To determine whether acetylsalicylic acid (ASA) inhibits hemostasis and platelet function in some individuals (ASA responders) but not in others (ASA nonresponders).In this two-part study, part 1 was a randomized, double-blind crossover study of the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::941cfbb3f2b82d1117152d1a95997ae1
https://pubmed.ncbi.nlm.nih.gov/7889440
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10
Is heparin the ideal anticoagulant for cardiopulmonary bypass? Dermatan sulphate may be an alternate choice
Autor: S J, Brister, F A, Ofosu, G J, Heigenhauser, F, Gianese, M R, Buchanan
Publikováno v: Thrombosis and haemostasis. 71(4)
Performance of cardiopulmonary bypass (CPB) during cardiac surgery requires the administration of high dose heparin to prevent CPB pump occlusion. However, this heparin use is associated with bleeding side-effects. Moreover, at the end of CPB, the he
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::fc6f7a1cef879c600cbab7dfd860c5e8
https://pubmed.ncbi.nlm.nih.gov/8052965
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Plný text Recenzováno Digitální knihovna AV ČR
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