Zobrazeno 1 - 7
of 7
pro vyhledávání: '"S J, Bielinski"'
Publikováno v:
European Heart Journal. 43
Background Heart failure (HF) is a complex clinical syndrome that affects over 60 million persons worldwide.1 The 5-year survival rate of HF is less than 50% irrespective of ejection fraction (EF) and the limitations of EF in sufficiently phenotyping
Autor:
Sarah C. Stallings, S. J. Bielinski, Daniel J. Schaid, Peggy D. Robertson, Mariza de Andrade, Rongling Li, James G. Linneman, Erin Austin, N. Nikroo, Iftikhar J. Kullo, David R. Crosslin, Safarova, Gail P. Jarvik, David Carrell, Eric B. Larson
Publikováno v:
European Heart Journal. 38
Autor:
Paul A. Decker, S. J. Bielinski, Naomi Q. Hanson, James S. Pankow, Alka M. Kanaya, Weihong Tang, Michael Y. Tsai, Nicholas B. Larson, Christina L. Wassel, Michèle M. Sale, C. Berardi
Publikováno v:
Diabetic medicine : a journal of the British Diabetic Association, vol 33, iss 7
Aims To test the hypothesis that soluble cellular adhesion molecules would be positively and independently associated with risk of diabetes. Methods Soluble levels of six cellular adhesion molecules (ICAM-1, E-selectin, VCAM-1, E-cadherin, L-selectin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::028979e42da797c3f1039b23e87205dd
https://escholarship.org/uc/item/6mt6m0fz
https://escholarship.org/uc/item/6mt6m0fz
Autor:
John Connolly, John C. Whittaker, Helen Ireland, Hynek Pikhart, Olaf H. Klungel, Claudia Langenberg, Juan P. Casas, Y. van der Graaf, Anne Peasey, Emelia J. Benjamin, Meena Kumari, Nicholas J. Timpson, Růžena Kubínová, P.J. Talmud, Nita G. Forouhi, Verschuren Wmm., KaWah Li, Engmann Jel., C Chung, Tina Shah, Damiano Baldassarre, Mika Kivimäki, Eric J. Brunner, John Hardy, Karoline Kuchenbaecker, Charles B. Eaton, Y. T. van der Schouw, Michael V. Holmes, S. J. Bielinski, Jaroslav A. Hubacek, P. A. Doevendans, Susan Redline, Berta Almoguera Castillo, Westendorp Rgj., Reecha Sofat, Yiran Guo, Leslie A. Lange, Debbie A Lawlor, James G. Wilson, John Gallacher, Richard S. Houlston, Martin Bobak, Maarten Leusink, Andrzej Pajak, George Davey Smith, James F. Meschia, Peter H. Whincup, Rebecca Hardy, Michael Marmot, Jeffrey W. Stephens, Brendan J. Keating, Diana Kuh, Delaney Jac., Mikhail I. Voevoda, N. C. Onland-Moret, Timothy M. Frayling, Hakon Hakonarson, S Bandenelli, Frank Dudbridge, G Jan de Borst, F G Fowkes, Migle Baceviciene, Gordon D.O. Lowe, Gerjan Navis, Alexander P. Reiner, Simon P. Mooijaart, Phil Howard, Boer Jma., Stephen E. Epstein, A. de Boer, Ian Ford, U de Faire, Abdonas Tamosiunas, Malcolm G. Dunlop, AB Singleton, Nicholas J. Wareham, Renate B. Schnabel, Johan Wouter Jukema, Naveed Sattar, Folkert W. Asselbergs, Fotios Drenos, Jutta Palmen, Christina L. Wassel, Sofia Malyutina, Daniel I. Swerdlow, Tetsu Tanaka, Ron T. Gansevoort, Julian Peto, Jenna Price, Bakker Sjl., Ian Tomlinson, Yun Li, Bengt Sennblad, Jackie A. Cooper, Jian'an Luan, Aroon D. Hingorani, JoAnn E. Manson, Roman Pfister, Mailand-van der Zee A-H., I. Mateo Leach, Anders Hamsten, Mike A. Nalls, Yoav Ben-Shlomo, Richard W Morris, Joe Devaney, Marlene C. W. Stewart, P A de Jong, Steve E. Humphries, Roman Topor-Madry, P. van der Harst, Jennifer G. Robinson, Andrew Wong, Luigi Ferrucci, Elena Tremoli, Ioanna Tzoulaki, Mary-Susan Burnett
Publikováno v:
The Lancet
The Lancet, 379(9822), 1214-1224. ELSEVIER SCIENCE INC
Hingorani, A D, Casas, J P, Price, J, Stewart, M & Dunlop, M & Tomlinson, I 2012, ' The interleukin-6 receptor as a target for prevention of coronary heart disease : a mendelian randomisation analysis ', The Lancet, vol. 379, no. 9822, pp. 1214-24 . https://doi.org/10.1016/S0140-6736(12)60110-X
The Lancet, 379(9822), 1214-1224. Elsevier Limited
Swerdlow, D I, Holmes, M V, Kuchenbaecker, K B, Engmann, J E L, Shah, T, Sofat, R, Guo, Y, Chung, C, Peasey, A & Timpson, N J & Casas, J P 2013, ' The interleukin-6 receptor as a target for prevention of coronary heart disease : a mendelian randomisation analysis ', Lancet, vol. 379, no. 9822, pp. 1214-1224 . https://doi.org/10.1016/S0140-6736(12)60110-X
The Lancet; Vol 379
The Lancet, 379(9822), 1214-1224. ELSEVIER SCIENCE INC
Hingorani, A D, Casas, J P, Price, J, Stewart, M & Dunlop, M & Tomlinson, I 2012, ' The interleukin-6 receptor as a target for prevention of coronary heart disease : a mendelian randomisation analysis ', The Lancet, vol. 379, no. 9822, pp. 1214-24 . https://doi.org/10.1016/S0140-6736(12)60110-X
The Lancet, 379(9822), 1214-1224. Elsevier Limited
Swerdlow, D I, Holmes, M V, Kuchenbaecker, K B, Engmann, J E L, Shah, T, Sofat, R, Guo, Y, Chung, C, Peasey, A & Timpson, N J & Casas, J P 2013, ' The interleukin-6 receptor as a target for prevention of coronary heart disease : a mendelian randomisation analysis ', Lancet, vol. 379, no. 9822, pp. 1214-1224 . https://doi.org/10.1016/S0140-6736(12)60110-X
The Lancet; Vol 379
SummaryBackgroundA high circulating concentration of interleukin 6 is associated with increased risk of coronary heart disease. Blockade of the interleukin-6 receptor (IL6R) with a monoclonal antibody (tocilizumab) licensed for treatment of rheumatoi
Publikováno v:
Clinical genetics. 86(1)
We provide a mini-review of how biobanks can support clinical genetics in the era of personalized medicine. We discuss types of biobanks, including disease specific and general biobanks not focused on one disease. We present considerations in setting
Autor:
Patricia B. Munroe, Muredach P. Reilly, Suzanne Rafelt, Caroline S. Fox, Diederick E. Grobbee, Jana V. van Vliet-Ostaptchouk, George Davey-Smith, Ingo Ruczinski, Haiqing Shen, Clara C. Elbers, Pieter A. Doevendans, Michael Boehnke, Niek Verweij, John Danesh, Archana Tare, Erin N. Smith, William C. Knowler, Tom R. Gaunt, Jessica van Setten, Meena Kumari, Claire E. Hastie, Jeanne M. McCaffery, Joseph T. Glessner, Sonia Shah, Mingyao Li, Aroon D. Hingorani, Marten H. Hofker, Annemieke W M Spijkerman, Richa Saxena, John Barnard, Rhonda M. Cooper-DeHoff, Matthijs F.L. Meijs, Matthew B. Lanktree, Garret A. FitzGerald, Mark I. McCarthy, Maximilian T. Lobmeyer, Diane Gilbert-Diamond, Paul Burton, Peter S. Sever, Neil R Poulter, Bernhard O. Böhm, Inga Peter, Philippa J. Talmud, David A. Morrow, Mary Pettinger, Olaf H. Klungel, Jane F. Ferguson, Braxton D. Mitchell, Martin Farrall, Mark C.H. De Groot, Thomas S. Price, Christa Meisinger, Sanjey R. Patel, Li Zhang, Nilesh J. Samani, Cliona Molony, Günther Silbernagel, Brendan J. Keating, Ian N. M. Day, Jutta Palmen, Marc S. Sabatine, Daniel J. Rader, M. Hadi Zafarmand, James B. Meigs, Taimour Y. Langaee, Kandice Kottke-Marchant, Wolfgang Koenig, Mika Kivimäki, Stephen S. Rich, Sean P. Curtis, Barbara Thorand, Lisa A. Gilhuijs-Pederson, Struan F.A. Grant, Toby Johnson, Thomas Illig, Mieke D. Trip, Erik P A Van Iperen, Alan R. Shuldiner, Benjamin F. Voight, Alice Stanton, Cecilia E. Kim, Yiran Guo, Robert Clarke, Gail P. Jarvik, Mark J. Caulfield, James G. Wilson, Stephen Newhouse, Michael W. Steffes, Winfried März, Jessica L. Mega, Clement E. Furlong, Robert A. Hegele, Eric E. Schadt, Sandosh Padmanabhan, Tushar Bhangale, Jane E. Ranchalis, David Altshuler, Christopher P. Nelson, Anthonius de Boer, Yan Gong, W. H. Linda Kao, S. J. Bielinski, Daphne L. van der A, Jeffery R. O'Connell, Fotios Drenos, Florianne Bauer, James S. Pankow, Berta Almoguera Castillo, Carl J. Pepine, Roy L. Silverstein, Yun Li, Olle Melander, Errol D. Crook, Quince Gibson, Joseph M. Zmuda, Deepak L. Bhatt, Yvonne T. van der Schouw, Jens Baumert, Denis C. Shields, Peter S. Braund, Christian Gieger, Solomon K. Musani, David S. Siscovick, Ashok Balasubramanyam, Thomas P. Cappola, Hakon Hakonarson, Juan P. Casas, Folkert W. Asselbergs, Marcus E. Kleber, Gerald W. Dorn, Jerome I. Rotter, Debbie A Lawlor, Danish Saleheen, Cisca Wijmenga, Anuj Goel, N. Charlotte Onland-Moret, Marcel Bruinenberg, Taylor Young, Ramakrishnan Rajagopalan, Donald W. Bowden, Asif Rasheed, Alexander P. Reiner, Anders Hamsten, Paul I.W. de Bakker, Anke-Hilse Maitland-van der Zee, Anna F. Dominiczak, Bruce H. R. Wolffenbuttel, Julie A. Johnson, Gordon S. Huggins, Hareesh R. Chandrupatla, Steve E. Humphries, Hugh Watkins, Gurunathan Murugesan, Pim van der Harst, Elisabeth A. Rosenthal
Publikováno v:
American journal of human genetics, 90(3), 410-425. Cell Press
American Journal of Human Genetics, 90(3), 410-425. CELL PRESS
The American Journal of Human Genetics; Vol 90
The American Journal of Human Genetics
American Journal of Human Genetics, 90(3), 410-425. CELL PRESS
The American Journal of Human Genetics; Vol 90
The American Journal of Human Genetics
To identify genetic factors contributing to type 2 diabetes (T2D), we performed large-scale meta-analyses by using a custom ∼50,000 SNP genotyping array (the ITMAT-Broad-CARe array) with ∼2000 candidate genes in 39 multiethnic population-based st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d19a12226e71db9569b3617d18ccabf7
https://pure.amc.nl/en/publications/largescale-genecentric-metaanalysis-across-39-studies-identifies-type-2-diabetes-loci(a8ec90d2-3787-4724-9da1-abf3c21cd2f8).html
https://pure.amc.nl/en/publications/largescale-genecentric-metaanalysis-across-39-studies-identifies-type-2-diabetes-loci(a8ec90d2-3787-4724-9da1-abf3c21cd2f8).html
Autor:
Gail P. Jarvik, Erin N. Smith, Clement E. Furlong, Roy L. Silverstein, Ramakrishnan Rajagopalan, Matthijs F.L. Meijs, Wolfgang Koenig, Joseph M. Zmuda, Jane E. Ranchalis, John Barnard, Christian Gieger, David A. Morrow, Lisa A. Gilhuijs-Pederson, Kandice Kottke-Marchant, Yun Li, Olle Melander, Errol D. Crook, David S. Siscovick, Asif Rasheed, Suzanne Rafelt, S. J. Bielinski, Inga Peter, Braxton D. Mitchell, Hakon Hakonarson, Anuj Goel, Thomas S. Price, Mieke D. Trip, Martin Farrall, Bernhard O. Böhm, Brendan J. Keating, Diederick E. Grobbee, M. Hadi Zafarmand, Berta Almoguera Castillo, Taimour Y. Langaee, Fotios Drenos, Alan R. Shuldiner, Stephen Newhouse, Jens Baumert, Michael Boehnke, Daniel J. Rader, Aroon D. Hingorani, Alexander P. Reiner, Marten H. Hofker, Cliona Molony, Jeanne M. McCaffery, Toby Johnson, Garret A. FitzGerald, Meena Kumari, Mark J. Caulfield, Ingo Ruczinski, Erik P A Van Iperen, Claire E. Hastie, Jessica L. Mega, Patricia B. Munroe, Diane Gilbert-Diamond, Marc S. Sabatine, Mark I. McCarthy, Robert Clarke, Sean P. Curtis, Jane F. Ferguson, Danish Saleheen, Winfried März, Nilesh J. Samani, Solomon K. Musani, Muredach P. Reilly, Annemieke W M Spijkerman, Daphne L. van der A, Li Zhang, William C. Knowler, Ashok Balasubramanyam, Cisca Wijmenga, Gurunathan Murugesan, Pim van der Harst, Matthew B. Lanktree, Barbara Thorand, Folkert W. Asselbergs, Tushar Bhangale, Benjamin F. Voight, Yan Gong, Pieter A. Doevendans, Maximilian T. Lobmeyer, N. Charlotte Onland-Moret, John Danesh, Anders Hamsten Robert Hegele, Marcel Bruinenberg, W. H. Linda Kao, Denis C. Shields, Taylor Young, Alice Stanton, Donald W. Bowden, Neil R Poulter, Jeffery R. O'Connell, Haiqing Shen, Florianne Bauer, Carl J. Pepine, Christa Meisinger, James S. Pankow, Mark C.H. De Groot, Günther Silbernagel, Clara C. Elbers, Yvonne T. van der Schouw, Quince Gibson, Thomas P. Cappola, Ian N. M. Day, Archana Tare, James B. Meigs, Struan F.A. Grant, Olaf H. Klungel, Jessica van Setten, Thomas Illig, Gerald W. Dorn, Jana V. van Vliet-Ostaptchouk, Michael W. Steffes, Stephen S. Rich, George Davey-Smith, Debbie A Lawlor, Marcus E. Kleber, Richa Saxena, Tom R. Gaunt, James G. Wilson, Sonia Shah, Sandosh Padmanabhan, Eric E. Schadt, David Altshuler, Niek Verweij, Rhonda M. Cooper-DeHoff, Paul Burton, Peter S. Sever, Sanjey R. Patel, Christopher P. Nelson, Jutta Palmen, Deepak L. Bhatt, Jerome I. Rotter, Juan P. Casas, Caroline S. Fox, Philippa J. Talmud, Steve E. Humphries, Paul I.W. de Bakker, Anna F. Dominiczak, Joseph T. Glessner, Mingyao Li, Bruce H. R. Wolffenbuttel, Mika Kivimäki, Cecilia E. Kim, Yiran Guo, Anthonius de Boer, Gordon S. Huggins, Peter S. Braund, Hareesh R. Chandrupatla, Hugh Watkins, Elisabeth A. Rosenthal, Anke-Hilse Maitland-van der Zee, Julie A. Johnson, Mary Pettinger
Publikováno v:
Europe PubMed Central
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d305ca991b14c94dda5fe7f6dac872a9
http://europepmc.org/abstract/PMC/PMC3322217
http://europepmc.org/abstract/PMC/PMC3322217