Zobrazeno 1 - 7
of 7
pro vyhledávání: '"S J, Berberich"'
Autor:
M D Cole, S J Berberich
Publikováno v:
Genes & Development. 6:166-176
Max is a heterodimeric partner of the Myc oncoprotein with sequence-specific DNA-binding activity. We found that the DNA-binding activity of bacterially expressed Max homodimers was inhibited in an ATP-dependent reaction by phosphorylation in vitro w
Publikováno v:
Journal of bioenergetics and biomembranes. 32(3)
NM23-H2/NDP kinase B has been identified as a sequence-specific DNA-binding protein with affinity for a nuclease-hypersensitive element of the c-MYC gene promoter (Postel et al., 1993). The ability of Nm23-H2 to activate c-MYC transcription in vitro
Publikováno v:
Vaccine. 17(9-10)
DNA molecules complexed with an asialoglycoprotein-polycation conjugate, consisting of asialoorosomucoid (ASOR) coupled to poly-L-lysine, can enter hepatocytes which bear receptors for ASOR. We used this receptor-mediated DNA delivery system to deliv
Autor:
C C, Wetzel, S J, Berberich
Publikováno v:
Oncology research. 10(3)
In this study the transactivation potential and DNA binding activities of p53 protein were examined following exposure of A2780 cells, a human ovarian carcinoma cell line, to the DNA damaging agent, cis-diamminedichloroplatinum II (cisplatin). The en
Publikováno v:
Cancer research. 57(22)
In response to genotoxic stress, the p53 tumor suppressor protein exerts a G1 cell cycle arrest that is dependent on its ability to transactivate downstream target genes. This p53-dependent G1 block is reversed by the binding of Mdm-2 to p53, prevent
Autor:
L D, Mayo, S J, Berberich
Publikováno v:
Oncogene. 13(11)
In this study, we set out to assess whether the p53 protein affects mdm-2 gene expression as F9 embryonal carcinoma cells differentiate into parietal endoderm cells. It was previously reported that F9 cells possess abundant levels of wild-type p53 an
Autor:
S J, Berberich, E H, Postel
Publikováno v:
Oncogene. 10(12)
We have isolated the transacting factor PuF that, through its interaction with a nuclease hypersensitive element (NHE) located upstream of the c-myc gene, transactivates the human c-myc gene in vitro (Postel et al., 1989). PuF was recently identified