Zobrazeno 1 - 10 of 16 pro vyhledávání: '"S I Ofoefule"'
1
Effect of hydrophilic diluents on the release profile of griseofulvin from tablet formulations
Autor: O N C, Umeh, J C, Azegba, S I, Ofoefule
Publikováno v: Indian Journal of Pharmaceutical Sciences
Studies have shown that when compressing drugs with low aqueous solubility, the solubility of diluents selected is very crucial as it influences the disintegration, dissolution and bioavailability of such drugs. Based on these reports, the present st
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4b78b61ad447e8dfba1c0394d7e85658
https://pubmed.ncbi.nlm.nih.gov/24591749
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3
Spectrophotometric and some thermodynamic parameters of the charge transfer complexation between chloranilic acid and chlorpheniramine
Autor: S I, Ofoefule, U, Ajali
Publikováno v: Bollettino chimico farmaceutico. 140(5)
The principle of charge transfer complexation involving a pi-acceptor (chloranilic acid) and an n-donor (chlorpheniramine) was utilized in the assay of the later in its pure form and in its tablet dosage forms. Some thermodynamic parameters of the co
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::fc5699bb0651611ffe3251269d29b7f6
https://pubmed.ncbi.nlm.nih.gov/11680092
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4
Prediction of in vivo bioavailability of six brands of ciprofloxacin film coated tablets using the concept dissolution efficiency (DE)
Autor: S I, Ofoefule, P O, Udeogaranya, J M, Okonta
Publikováno v: Bollettino chimico farmaceutico. 140(3)
A comparative in vitro dissolution efficiencies (DE) of six commercial brands of ciprofloxacin tablets were evaluated in acetic acid and phosphate buffer (pH 7.4) and results obtained were used in ranking of their probable in vivo bioavailability. Th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::229b56c291fb9728d5647318ae2de59f
https://pubmed.ncbi.nlm.nih.gov/11486612
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5
Effect of activated charcoal on isoniazid absorption in rabbits
Autor: S I, Ofoefule, L C, Onuoha, M J, Okonta, P O, Udeogaranya, O E, Orisakwe
Publikováno v: Bollettino chimico farmaceutico. 140(3)
The effect of activated charcoal on gastrointestinal absorption of isoniazid (INH) was determined quantitatively in rabbits. The presence of activated charcoal resulted to about 40% reduction of INH bioavailability as was indicated by reduction in th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5b16595f25013135b17d96d6e3bda4f0
https://pubmed.ncbi.nlm.nih.gov/11486611
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6
A comparative study of modified starches in direct compression of a poorly water soluble drug (hydrochlorothiazide)
Autor: I S, Okafor, S I, Ofoefule, O K, Udeala
Publikováno v: Bollettino chimico farmaceutico. 140(1)
The direct compression properties of four modified starches in hydrochlorothiazide (HCTZ) tablets were studied. The starches were obtained locally from common plant sources and were modified through physicochemical treatment. Each modified starch was
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::687e2b08b237afc3660808bd665bb3c4
https://pubmed.ncbi.nlm.nih.gov/11338775
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7
A comparative study of modified starches in direct compression of a water soluble drug-chloroquine phosphate
Autor: I S, Okafor, S I, Ofoefule, O K, Udeala
Publikováno v: Bollettino chimico farmaceutico. 139(6)
Some in vitro properties of chloroquine phosphate tablets formulated with four modified starches were investigated. The drug was formulated as tablets containing 250 mg of chloroquine phosphate and produced by the direct compression technique. The st
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::498221ba4b9eb280d78bc047a00270ec
https://pubmed.ncbi.nlm.nih.gov/11213430
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8
Use of acryclic and metacrylic acid derivatives as sustained release matrices for theophylline hydrate tablets
Autor: S I, Ofoefule, A, Chukwu
Publikováno v: Bollettino chimico farmaceutico. 138(10)
Carbopol 941, an acrylic acid polymer and "Eudragit L100-55, a metacylic acid polymer, were compared as sustained release matrix devices for theophylline hydrate tablets. The theophylline tablets containing 0 to 30% of either of the polymer were prep
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::45d22bd17bc6b37f3c831006baea1742
https://pubmed.ncbi.nlm.nih.gov/10765469
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9
Effect of direct compression excipients on the stability of ascorbic acid (vitamin c) tablets
Autor: S I, Ofoefule, V O, Chukwube, A A, Attama
Publikováno v: Bollettino chimico farmaceutico. 138(8)
The effects of four directly compressible excipients such as Avicel, Dipac, Ditab and Emdex on the stability of ascorbic acid tablets were evaluated. Ascorbic acid tablets were formulated by the direct compressive method at constant temperature and p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0867a1aaa9ad4cc48d3383bc36133afd
https://pubmed.ncbi.nlm.nih.gov/10622107
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10
Adsorption studies of ciprofloxacin: evaluation of magnesium trisilicate, kaolin and starch as alternatives for the management of ciprofloxacin poisoning
Autor: S I, Ofoefule, M, Okonta
Publikováno v: Bollettino chimico farmaceutico. 138(6)
In vitro experiments were performed to investigated the extend of adsorption of ciprofloxacin to kaolin, magnesium trislilicate and to a starch obtained from the tubers of Tacca involucrata (Tacca starch) and to explore the effect of varying pH on th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6b2bb0f90fec713685a1260a51185c88
https://pubmed.ncbi.nlm.nih.gov/10464971
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