Selective Depletion of Alloreactive T Cells Leads to Long-Term Islet Allograft Survival across a Major Histocompatibility Complex Mismatch in Diabetic Mice

Autor: M. Hu, J. Wu, G. Y. Zhang, Y. M. Wang, D. Watson, S. Yi, W. J. Hawthorne, P. J. O'connell, S. I. Alexander

Publikováno v: Cell Transplantation, Vol 22 (2013)

Islet cell transplantation as a therapy for type 1 diabetes has been limited by progressive graft loss. Significant immunosuppression including T-cell ablation has been used in an attempt to limit islet rejection. Here, we show that CD3 + lymphocytes

Externí odkaz: https://doaj.org/article/4d7e4dd933104cefa26f9f7ac66cc933

Regulatory T cells (PP-045)

Autor: E. Tasaki, Y. Okuno, E. M. Bertram, H. Isaka, S. Delbauve, T. Nakashima, K. A. Newell, J. C. Antvorskov, H. Fan, S. Kawashima, G. Ying, D. Horwitz, T. Thomas, M. Feuerer, Akihiko Yoshimura, C. Elly, K. Wang, T. Kanzaki, K. Buschard, T. P. Arstila, T. Huenig, F. Mair, N. Perdue, J. Sprent, L. Lu, L. Akahira, Y. Yoshida, H. Feng, W. Wang, Howard L. Weiner, Thorsten Buch, T. Laurinolli, D. Lim, F. X. Qin, X. Cao, J. Bártová, Y. m. Cao, I. R. van Driel, S. Hong, C. Tsao, L. M. Kastner, E. M. Ross, J. Wang, T. Honda, S. Park, Y. Chung, S. Schwele, R. Haque, B. Li, T. Yoshikawa, Matthew C. Cook, B. H. Hahn, M. G. Netea, Aleksandar Bulog, I. Iwamoto, J. Liu, P. Fundova, M. Kibata, Y. Lee, C. C. Goodnow, F. Conti, J. S. LeMasurier, Jeffrey A. Bluestone, J. Kie, K. Soejima, N. Erfani, X. R. Zhou, R. J. Steptoe, I. Kim, M. A. Fernandez, C. S. Constantinescu, S. Bauchiero, X. Jin, D. S. Y. Tan, Holly A. Bolton, S. Hu, L. R. Wedderburn, V. Flamand, Z. Liu, K. Sugimura, S. Kunkel, J. M. Rolland, Takatoku Oida, T. Ho, Tobias Bopp, L. Zheng, Y. Li, S. Shen, K. Michishita, M. Shin, R. Germain, Y. Tang, S. Klein-Hessling, Q. h. Wang, X. P. Peng, S. Nakamura, Daniel J. Campbell, Irma Joosten, X. Jiang, M. Braitch, Z. Yao, Masahide Hamaguchi, V. Pancre, H. Lee, Y. Zheng, Y. Cui, W. Müller, R. White, H. Yue, Ai Harashima, J. Perheentupa, M. Tomura, A. T. Endharti, S. Gattenloehner, Kenji Kabashima, M. Goldman, Z. Sarraf, Mihoko Shibuya, T. Sasaki, Y. Kanno, M. Yamamoto, J. Lee, G. Y. Zhou, A. M. Fischer, Y. Kwon, Christophe Benoist, Z. Chen, M. Nakatsugawa, Y. Liu, Y. Park, K. Yamamoto, Dirk H. Busch, C. S. Constantinecsu, T. Hamamoto, A. Carpentier, Y. Zhou, Hans-Dieter Volk, Tomohisa Okamura, J. Tsukada, K. Webster, E. Rabellino, I. Debock, F. Lin, Vladimir Mićović, T. Wakayama, Josef Bodor, H. Bae, G. Metzner, A. Kwan, Ari Waisman, C. Pecli, C. Wu, J. Song, S. Imoto, S. Han, H. Tanizaki, M. Mariotti-Ferrandiz, J. Paik, S. M. Salonen, K. Kawahata, B. Adams, M. H. Nyirenda, C. L. Hardy, K. Isobe, L. M. Lu, J. R. Killebrew, O. Morales, D. P. Funda, A. R. Kendal, A. McNally, R. A. DePinho, Ryuji Iida, N. Sasaki, S. Kim, N. Yang, L. H. Rossi, G. Brestrich, L. Hsu, N. Wada, C. Lu, C. B. Schmidt-Weber, V. Seyfert-Margolis, A. J. van der ven, T. Nakatsura, V. Nikolaev, H. Collins, A. R. Kitching, Carla Jones, B. Yen, Z. J. Jiao, C. Chan, T. Nakagaki, M. Takeuchi, Hirofumi Shoda, G. Lee, G. Wang, T. V. Hogan, M. Plebanski, F. Stenard, F. Liu, A. Suto, T. Otani, K. Tsuji-Takayama, D. E. Furst, Y. Takasaki, Tim Sparwasser, A. Tanaka, M. Asakawa, J. H. Louie, D. Brand, D. W. Dwyer, S. Nakano, A. Okamoto, M. Imamura, L. Chi, C. Zhu, J. Zhu, P. Roubal, S. Dharancy, M. Dohi, E. Kekäläinen, S. I. Alexander, H. Kojima, Dong Han, Q. Wang, N. Delhem, K. Takahashi, D. M. Heery, J. Sun, N. Sakemura, B. Gran, T. Toraya, A. Feng, X. Shen, C. A. Garcia Santana, H. Itoh, S. Zheng, N. MacDonald, U. Behn, A. Facciabene, B. Chiang, W. Kastenmuller, M. W. Leung, Shuji Sumitomo, X. Qu, S. Huang, R. Molinaro, A. Kokešová, M. Bozza, S. Z. Josefowicz, K. Bourcier, D. Bourges, K. Hirose, S. Rahimifar, F. Yamasaki, K. Nistala, E. Serfling, E. Schmitt, Friederike Berberich-Siebelt, Y. Wang, G. Coukos, F. Gross, I. Drexler, L. Yang, T. Gogishvili, S. Kagami, Y. Harada, H. Nakajima, E. Market, Y. Chen, A. Sledzinska, Lin Tian, Amy L. Putnam, F. Cunha, Anthony E.J. Dubois, M. I. Greene, S. Kamei, J. J. Lafaille, D. Kolodin, P. A. Gleeson, Ranjeny Thomas, W. Bolton, Xiao-Sen Li, I. Osawa, C. Miroux, Y. Kang, J. Drbohlav, A. Chaudhry, C. F. Benjamim, C. Kang, A. Ghaderi, G. Zhang, R. P. Singh, M. Hong, S. R. Holdsworth, L. Sanvito, L. Wang, J. j. Wu, T. Kobata, M. Kuo, B. Kim, M. Michels, A. I. Kokaji, Z. Li, W. Shi, J. Yao, X. Xia, W. Chang, S. Choi, R. Nakagawa, Y. y. Pan, M. Vaeth, C. Canetti, F. Lei, P. Hsu, J. Alves-Filho, S. Hori, A. Šalaková, B. L. Wang, J. Wilkinson, P. Zdziarski, M. Fairhurst, Keishi Fujio, X. Zheng, H. Suzuki, R. K. Dinesh, Shimon Sakaguchi, Z. Jiang, S. Hemmers, B Fazekas de St Groth, M. Zelman-Femiak, H. Moncrieffe, L. Han, J. Park, M. Suzuki, S. Eaton, D. Sakurai, T. Inoue, F. Lhommé, S. Nishimoto, Ines Mrakovčić-Šutić, R. Mohamud, Matthias Klein, S. D'Costa, R. E. O'Hehir, N. Morishima, J. Cha, M. Schmueck, M. Uchiyama, K. Imi, H. Hase, E. Boleslowski, A. Liston, C. Park, P. Reinke, C. Shen, H. Wakashin, D. A. Horwitz, Ohkura Naganari, Herman Waldmann, A. Okochi, A. Khoo, I. Kubajewska, J. Seoh, A. Roemhild, Alexander Y. Rudensky, Diane Mathis, J. A. Altin, C. Liu, M. Lohse, T. Shimada, B. Yang, W. Liu, L. Turka, M. Kweon, G. Gasteiger, Hans J. P. M. Koenen, Y. Kim, S. Okuda, Burkhard Becher, Osami Kanagawa

Publikováno v: International Immunology. 22:iii11-iii24

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::879e0fc9b64ca8225e7e310776276089
https://doi.org/10.1093/intimm/dxq225

Regulatory interactions of alphabeta and gammadelta T cells in glomerulonephritis

Autor: A R, Rosenkranz, S, Knight, S, Sethi, S I, Alexander, R S, Cotran, T N, Mayadas

Publikováno v: Kidney international. 58(3)

Several lines of evidence suggest that cellular immune mechanisms contribute to glomerulonephritis.The roles of alphabeta and gammadelta T cells in the pathogenesis of glomerulonephritis were investigated in a model of nephrotoxic nephritis in mice d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5a1ceb991939f5d1390fa89bb2aaa97e
https://pubmed.ncbi.nlm.nih.gov/10972670

Indirect allorecognition of major histocompatibility complex allopeptides in human renal transplant recipients with chronic graft dysfunction

Autor: J P, Vella, M, Spadafora-Ferreira, B, Murphy, S I, Alexander, W, Harmon, C B, Carpenter, M H, Sayegh

Publikováno v: Transplantation. 64(6)

It has been suggested that T cells primed by processed donor major histocompatibility complex antigen (the "indirect" pathway of allorecognition) may be responsible for mediating chronic allograft rejection. The purpose of this study was to develop a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6ea25124fbc712ca2ec14a25f6bb8008
https://pubmed.ncbi.nlm.nih.gov/9326400

HETEROLOGOUSLY PRIMED T CELLS ARE REQUIRED TO INITIATE CD4-DEPENDENT SKIN AND ISLET GRAFT REJECTION

Autor: B. Roediger, Fazekas B. de St Groth, Y. W. Loh, D. Gracey, S. I. Alexander

Publikováno v: Transplantation Journal. 90:144

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4019e1d425645e15e6686b991a61cd81
https://doi.org/10.1097/00007890-201007272-00275