Zobrazeno 1 - 10
of 51
pro vyhledávání: '"S I, Shram"'
Autor:
G. I. Kovalev, Yu. A. Zolotarev, A. K. Dadayan, S. I. Shram, A. A. Abdullina, E. V. Vasileva, G. B. Kolyvanov, V. P. Zherdev
Publikováno v:
Фармакокинетика и Фармакодинамика, Vol 0, Iss 3, Pp 48-56 (2019)
Resume. The objective of this study is to evaluate pharmacokinetic parameters of tritium-labeled cycloprolylglycine [3H] -CPG following intravenous bolus administration of 5.7 μg (2 mCi). [3H] -CPG was prepared by solid-state catalytic isotopic exch
Externí odkaz:
https://doaj.org/article/3262be60abe84f80b34cdda9694da5f0
Publikováno v:
Тонкие химические технологии, Vol 3, Iss 5, Pp 99-103 (2008)
The photoaffine arylazide derivatives of peptides semax and Pro-Gly-Pro have been synthesized. It was shown that these compounds have cytoptotective action in culture of PC12 cells under conditions of oxidative stress.
Externí odkaz:
https://doaj.org/article/89016a3349a64341a85241c3e81def5c
Publikováno v:
Тонкие химические технологии, Vol 2, Iss 4, Pp 78-82 (2007)
The photoaffine arylazide semax derivative has been synthesized using paminobenzoic acid and semax as starting compounds
Externí odkaz:
https://doaj.org/article/9fdb790fac094430b860164c0c8f679f
Autor:
Yu. A. Zolotarev, A. K. Dadayan, N. F. Myasoedov, Valery M. Lipkin, S. I. Shram, V. S. Kozik, V. N. Azev, A. P. Bogachouk
Publikováno v:
Russian Journal of Bioorganic Chemistry. 45:514-521
Pharmacokinetics of the promising antitumor peptide HLDF-6-AA (Ac-ThrGlyGluAsnHisArg-NH2) was studied using its uniformly tritiated derivative. Experiments were performed on male Wistar rats, Balb/c mice and Chinchilla rabbits. The tritium labeled pe
Autor:
N. F. Myasoedov, V. N. Azev, I. Yu. Nagaev, Valery M. Lipkin, V. S. Kozik, A. P. Bogachouk, S. I. Shram, Yu. A. Zolotarev, A. K. Dadayan
Publikováno v:
Russian Journal of Bioorganic Chemistry. 45:347-352
HLDF-6 hexapeptide, which corresponds to the 41TGENHR46 fragment of human leukemia differentiation factor (HLDF), shows a wide range of neuroprotective, normalizing, anxiolytic, nootropic and antitumor activities. A promising drug with antitumor acti
Autor:
A. S. Efremova, Nadezda M Podvalnaya, Nadya G. Gurskaya, Konstantin A. Lukyanov, Dmitry A. Gorbachev, Artem V. Luzhin, S. I. Shram, Elena V. Zagaynova, Varvara V. Dudenkova, Ekaterina O. Serebrovskaya, Omar L. Kantidze
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 14
International Journal of Molecular Sciences, Vol 21, Iss 5004, p 5004 (2020)
Volume 21
Issue 14
International Journal of Molecular Sciences, Vol 21, Iss 5004, p 5004 (2020)
Poly-(ADP-ribosyl)-ation (PARylation) is a reversible post-translational modification of proteins and DNA that plays an important role in various cellular processes such as DNA damage response, replication, transcription, and cell death. Here we desi
Autor:
V.V. Ashapkin, Alexander V. Markov, Olga Yamskova, E.V. Sorokina, S. I. Shram, T S Putyatina, Vassily A. Lyubetsky, Mikhail Yu. Vyssokikh, G. A. Shilovsky
Publikováno v:
Biochemistry. Biokhimiia. 84(12)
Age-related dysfunctions are accompanied by impairments in the mitochondrial morphology, activity of signaling pathway, and protein interactions. Cardiolipin is one of the most important phospholipids that maintains the curvature of the cristae and f
Publikováno v:
Molecular Biology. 51:602-613
Autor:
L. A. Andreeva, I. Yu. Nagaev, S. I. Shram, K. V. Shevchenko, N. F. Myasoedov, V. P. Shevchenko
Publikováno v:
Doklady Biochemistry and Biophysics. 473:151-154
It was shown that the neuroactive peptide 5-oxo-Pro-Arg-Pro (5-oxo-PRP) is detected in the brain in the time interval of 5-120 min after it was intravenously or intranasally administered to rats; the maximum concentration of labeled tripeptide in the
Publikováno v:
Молекулярная биология. :683-695
miRNA expression over different time periods (24 and 48 h) using the quantitative RT-PCR and deep sequencing has been evaluated in a model of photochemically induced thrombosis. A combination of two approaches allowed us to determine the miRNA expres