Výsledky vyhledávání - "S I, RAPAPORT"

Properties of factor VIIa/tissue factor complexes in an umbilical vein model

Autor: F E, Almus, L V, Rao, R A, Fleck, S I, Rapaport

Publikováno v: Blood. 76:354-360

An umbilical vein model was designed in which washed vein segments are filled with a reaction mixture containing factor VIIa, Ca(+)+, and a substrate, either 3H-factor IX or 3H-factor X. The vein wall provides the tissue factor (TF) for factor VIIa/T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62eba46aba88adfda75248c4372a5ac6
https://doi.org/10.1182/blood.v76.2.354.bloodjournal762354

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Disseminated intravascular coagulation in rabbits induced by administration of endotoxin or tissue factor: effect of anti-tissue factor antibodies and measurement of plasma extrinsic pathway inhibitor activity

Autor: T A, Warr, L V, Rao, S I, Rapaport

Publikováno v: Blood. 75:1481-1489

Rabbits were given polyclonal anti-tissue factor (TF) immunoglobulin G (IgG) before an injection of endotoxin to test the hypothesis that TF triggers disseminated intravascular coagulation (DIC) after endotoxin. The rabbits had been prepared with cor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38890c65c3b9a75646846bc1c3566870
https://doi.org/10.1182/blood.v75.7.1481.bloodjournal7571481

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Factor VIIa-catalyzed activation of factor X independent of tissue factor: its possible significance for control of hemophilic bleeding by infused factor VIIa

Autor: L V, Rao, S I, Rapaport

Publikováno v: Blood. 75:1069-1073

Infusing factor VIIa (FVIIa) has been reported to control bleeding in hemophilic patients with factor VIII (FVIII) inhibitors. This is difficult to attribute to an enhanced FVIIa/tissue factor (TF) activation of factor X, since in vitro studies sugge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c68289a3be98a5b6f7db51cb4b204f80
https://doi.org/10.1182/blood.v75.5.1069.bloodjournal7551069

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Correction of excessive anticoagulation with low-dose oral vitamin K1

Autor: R T, Weibert, D T, Le, S R, Kayser, S I, Rapaport

Publikováno v: Annals of internal medicine. 126(12)

Despite earlier acceptance of oral vitamin K1 (phytonadione) for the treatment of excessive anticoagulation, some recent guidelines do not recommend its use.To reevaluate the efficacy of oral vitamin K1 in correcting excessive anticoagulation.Case se

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9239491fef071b0cef0b034e2bb1b7a
https://pubmed.ncbi.nlm.nih.gov/9182473

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Reliability of a modified tissue factor-dependent factor V assay for activated protein C resistant factor Va using a calcium-containing thromboplastin

Autor: D T, Le, K J, Donnelly, N, Wu, B K, Sevilla, S I, Rapaport

Publikováno v: Thrombosis and haemostasis. 77(3)

The original tissue factor-dependent factor V assay for activated protein C resistant factor Va (Blood 1995; 85: 1704-1711) has been modified to use a calcium containing thromboplastin and to express results as an observed to expected ratio (Obs/Exp.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d2da973412b16e18cd9eec5d7d5fe4fb
https://pubmed.ncbi.nlm.nih.gov/9065998

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Studies of the activation of factor VII bound to tissue factor

Autor: L V, Rao, T, Williams, S I, Rapaport

Publikováno v: Blood. 87(9)

Experiments were performed to evaluate activation of factor VII bound to relipidated tissue factor (TF) in suspension and to TF constitutively expressed on the surface of an ovarian carcinoma cell line (OC-2008). Activation was assessed by measuring

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e1f8136054debc69f38a70f20231b912
https://pubmed.ncbi.nlm.nih.gov/8896439

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