Zobrazeno 1 - 10
of 115
pro vyhledávání: '"S I, Katz"'
Publikováno v:
The Journal of Immunology. 154:4851-4856
Numerous studies have demonstrated that ultraviolet B (UVB) irradiation has profound effects on the skin and systemic immune systems. Because many of the effects of UVB result in suppression of contact sensitivity responses and because IL-10 induces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6061dd1c5eafd17fc8a4d59d9054d2ea
https://doi.org/10.4049/jimmunol.154.9.4851
https://doi.org/10.4049/jimmunol.154.9.4851
Publikováno v:
The Journal of Immunology. 154:3506-3515
APC dysfunction may be important in immune dysregulation associated with HIV disease. Langerhans cells, epidermal APC, can be infected with HIV, although their function in HIV-infected persons has not been studied. Therefore, we studied the immunolog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30975be55fe6755ea4c1c10eb681a8f7
https://doi.org/10.4049/jimmunol.154.7.3506
https://doi.org/10.4049/jimmunol.154.7.3506
Publikováno v:
The Journal of Immunology. 154:1232-1238
Although protein-derived nominal Ags have, in many instances, been precisely determined, the epitopes recognized by hapten-specific CD4+ T cells responsible for contact sensitization have not been defined. To better understand the nature of the preci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4bd31464d7197eff9abb0eab56915fe5
https://doi.org/10.4049/jimmunol.154.3.1232
https://doi.org/10.4049/jimmunol.154.3.1232
Publikováno v:
The Journal of Immunology. 153:110-116
Epidermal Langerhans cells are derived from cells of bone marrow origin and, as the primary APC population in the skin, are responsible for initiation of many immune responses. Consequently, cell surface expression of MHC Ags by Langerhans cells is c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::053ec2f15366cbdb175549670070f97d
https://doi.org/10.4049/jimmunol.153.1.110
https://doi.org/10.4049/jimmunol.153.1.110
Publikováno v:
The Journal of Immunology. 152:3264-3270
Heat-stable antigen (HSA), expressed by activated B cells, has been described as a costimulatory molecule for CD4+ T cells. Because epidermal Langerhans cells (LC) are known to express HSA, we determined whether LC HSA also served as a costimulator o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef5d134c0538578183d88f7da9a74cc3
https://doi.org/10.4049/jimmunol.152.7.3264
https://doi.org/10.4049/jimmunol.152.7.3264
Publikováno v:
The Journal of Immunology. 151:2390-2398
IL-10 is a product of activated keratinocytes and is released during the induction phase of contact sensitivity. As IL-10 effects have been described as being mediated by APC, we investigated effects of IL-10 on epidermal Langerhans cells (LC), the r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01ef2217310c34c28f6755389f42a5f7
https://doi.org/10.4049/jimmunol.151.5.2390
https://doi.org/10.4049/jimmunol.151.5.2390
Publikováno v:
The Journal of Immunology. 150:3698-3704
Langerhans cells (LC) are Ag-presenting cells required for induction of primary immune responses in skin. After activation by Ag, LC express increased levels of MHC class II Ag, exhibit increased accessory cell activity, and migrate to regional lymph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::201c31d92175d737916a6abc42ac1201
https://doi.org/10.4049/jimmunol.150.9.3698
https://doi.org/10.4049/jimmunol.150.9.3698
Publikováno v:
The Journal of Immunology. 149:92-95
It has previously been demonstrated that the epidermis is a rich source of proinflammatory cytokines and growth factors and that complex interactions between these factors may affect inflammatory responses in skin. To investigate whether IL-10 (cytok
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e191cc9d7309be5ef874a99cf8b23354
https://doi.org/10.4049/jimmunol.149.1.92
https://doi.org/10.4049/jimmunol.149.1.92
Autor:
A A Gaspari, S I Katz
Publikováno v:
The Journal of Immunology. 147:4155-4161
Because our previous in vitro studies of hapten-modified Ia+ keratinocytes (KC) indicated that these cells induced anergy in Ag-specific Th1 cells, we assayed such cells for their ability to induce unresponsiveness in an in vivo animal model system o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b10017b1cdebe61241f5f42342b4dce2
https://doi.org/10.4049/jimmunol.147.12.4155
https://doi.org/10.4049/jimmunol.147.12.4155
Publikováno v:
The Journal of Immunology. 146:2479-2487
There is controversy regarding the ability of short term (2 to 3 days) cultured epidermal Langerhans cells (cLC) to process and present intact protein Ag to primed T cells. Some studies have shown that cLC are potent APC for both haptens and intact p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::609e0f591f9d7ced049638080c01419d
https://doi.org/10.4049/jimmunol.146.8.2479
https://doi.org/10.4049/jimmunol.146.8.2479