Zobrazeno 1 - 7
of 7
pro vyhledávání: '"S I, Detre"'
Autor:
S. I. Detre, Brian M. J. Foxwell, G. Wilson, Fiorenzo Stirpe, David N. Skilleter, J. A. Forrester, Alex N. F. Brown, Philip E. Thorpe
Publikováno v:
European Journal of Biochemistry. 147:197-206
Attempts to target antibody-ricin conjugates (immunotoxins) to designated cell types in vivo may be thwarted by their rapid clearance by hepatic reticuloendothelial cells which have receptors that recognise oligosaccharide side chains on the toxin. T
Autor:
S. I. Detre, Walter C. J. Ross, Philip E. Thorpe, D. C. Edwards, Anthony J. S. Davies, Fiorenzo Stirpe, Alex N. F. Brown, Alan J. Cumber
Publikováno v:
European Journal of Biochemistry. 116:447-454
Gelonin, a plant protein which can powerfully reduce the protein-synthetic capacity of ribosome preparations, was covalently coupled to anti-Thy1.2 antibody. The conjugate was prepared using N-succinimidyl-3-(2-pyridyldithio)propionate which generate
Publikováno v:
British Journal of Cancer
Five out of 18 primary explants of human carcinomata obtained at operation have been grown progressively for a minimum of one month in thymectomized, x-irradiated mice reconstituted with syngeneic bone marrow and subsequently treated also with anti-t
Publikováno v:
British Journal of Cancer
alpha1-Foetoprotein (AFP) levels have been measured by radioimmunoassay in the serum of 153 male patients with gonadal and extragonadal germ cell tumours. Thirty-five patients with pure seminoma, and 34 patients with teratoma but without any postoper
Publikováno v:
Haematology and blood transfusion. 28
Publikováno v:
Haematology and Blood Transfusion / Hämatologie und Bluttransfusion ISBN: 9783540118589
The advent of cell fusion techniques for producing monoclonal antibodies has stimulated world-wide effort in the search for antibodies with specificity for neoplastic cells. In parallel, a number of laboratories have attempted to devise ways of attac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84fec76a38efc805dd5bb0dce0916be5
https://doi.org/10.1007/978-3-642-68761-7_24
https://doi.org/10.1007/978-3-642-68761-7_24
Autor:
S. I. Detre
Publikováno v:
Immunodeficient Animals for Cancer Research ISBN: 9781349050161
One use of the immunodeficient mouse in cancer research is as a vehicle for the continuation of human tumours for further studies. Thymus-deprived (B) mice of diverse types (Castro, 1972; Detre and Gazet, 1973; Franks et al., 1976), immunosuppressed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87314235c4f47dd3bfe0eabb0ced1064
https://doi.org/10.1007/978-1-349-05014-7_7
https://doi.org/10.1007/978-1-349-05014-7_7