Zobrazeno 1 - 10 of 144 pro vyhledávání: '"S I, Ankier"'
1
The Pharmacokinetics of Suriclone after Single- and Multiple-Dose Administration in Healthy Elderly Volunteers
Autor: P. Wijayawardhana, P. Chevalier, Peter Crome, S. I. Ankier, P. Guillet, P. Dowell
Publikováno v: Drugs & Aging. 3:436-440
Healthy elderly people aged 70 or more should receive a starting dosage of the anxiolytic drug suriclone half that recommended for younger people; frail or ill elderly people may require further dosage reduction. These conclusions were based on a stu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::244cc50ce3c9952ba4c273bd21bca71d
https://doi.org/10.2165/00002512-199303050-00005
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2
ICI 141,292 (epanolol) —pharmacokinetics after single and repeated oral administration in the elderly with moderate renal impairment
Autor: R Crome, I. D. Cockshott, S. I. Ankier, M. S. Laher, G. S. Rakhra
Publikováno v: European Journal of Clinical Pharmacology. 39:71-74
The pharmacokinetics of ICI 141,292 (epanolol) were studied over 3 days after a single oral 200 mg dose and then over 24 h after 12 consecutive daily oral 200 mg doses in 16 elderly subjects (aged 65 to 94 years) with moderate renal impairment (mean
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a9f331ad01759de66a525cc11f109ae
https://doi.org/10.1007/bf02657061
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3
A pharmacokinetic and dynamic study of single nightly doses of conventional and controlled release formulations of trazodone
Autor: S I, Ankier, S J, Warrington, J M, Sneddon
Publikováno v: Methods and findings in experimental and clinical pharmacology. 13(2)
We studied the pharmacokinetics and dynamics of single evening oral doses of conventional capsules (100 mg) and a controlled release formulation (150 mg) of trazodone in 12 fasting and non-fasting young healthy volunteers. When corrected for the diff
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9591aa2e6ea2176226daf8dcf29cd355
https://pubmed.ncbi.nlm.nih.gov/2072810
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4
The physicians' role in the clinical development of new medicines
Autor: S. J. Warrington, S. I. Ankier
Publikováno v: Postgraduate medical journal. 66(771)
At one time the process of testing new medicines was the province mainly of physicians in teaching hospitals, but this is no longer so: physicians in district hospitals and in general practice are increasingly involved because they are caring for the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fbc80b9cece22114b56b02fc40231b3
https://pubmed.ncbi.nlm.nih.gov/2190200
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8
A Multicentre Open Comparison of Isosorbide-5-Mononitrate and Nifedipine Given Prophylactically to General Practice Patients with Chronic Stable Angina Pectoris
Autor: D. F. Woodings, S. J. Warrington, S. I. Ankier, L. Fay
Publikováno v: Journal of International Medical Research. 17:172-178
A total of 126 patients from general practice with chronic stable angina pectoris entered the treatment phase of this open, randomized, crossover comparison of 20 mg isosorbide-5-mononitrate, and 20 mg nifedipine. Both treatments were given orally, t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaf46178806df5a0716f179ed818a043
https://doi.org/10.1177/030006058901700210
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