Zobrazeno 1 - 10
of 15
pro vyhledávání: '"S I, Abrams"'
Autor:
S I, Abrams, M J, Dobrzanski, D T, Wells, S F, Stanziale, S, Zaremba, L, Masuelli, J A, Kantor, J, Schlom, L ], Masuelle L [corrected to Masuelli
Publikováno v:
European Journal of Immunology. 25:2588-2597
Alterations in the ras p21 protein have been associated with both rodent and human neoplasia. Thus, mutated ras p21 proteins may bear unique antigenic epitopes for immune recognition, such as by T cells, which have been implicated in host antitumor a
Autor:
S I Abrams, J H Russell
Publikováno v:
The Journal of Immunology. 146:405-413
We have been exploring the hypothesis that T lymphocytes have the potential to mediate immune damage through nonlytic disruption of tissue organization. In this report, we have examined the ability of purified, primary cultures of alloreactive CD4+ T
Publikováno v:
Seminars in oncology. 26(6)
A new era involving the evaluation of recombinant vaccines for colon cancer has begun with the concurrent emergence of insights and technologies in the fields of molecular biology and immunology. These advances include (I) the identification and clon
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 160(5)
We recently identified a murine mutant Ras p21 CD8+ CTL epitope reflecting residues 4 to 12, containing the mutation of Gly to Val at codon 12, that bound weakly to H-2Kd in vitro and generated a weak primary CTL response in immunized BALB/c mice. He
Publikováno v:
Seminars in oncology. 23(1)
The ras p21 proto-oncogenes (ie, K-ras, H-ras, N-ras) encode a family of proteins vital to cellular signaling and function. Point mutations in these genes have been found in a wide diversity of human cancers, suggesting a strong association in the de
Publikováno v:
Cancer research. 55(16)
At least two signals are required for the activation of naive T cells by antigen-bearing target cells: an antigen-specific signal, delivered through the T-cell receptor, and a costimulatory signal delivered through the T-cell surface molecule CD28 by
Publikováno v:
The Journal of Immunology. 183:2884-2884
Autor:
S I, Abrams, J H, Russell
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 146(2)
We have been exploring the hypothesis that T lymphocytes have the potential to mediate immune damage through nonlytic disruption of tissue organization. In this report, we have examined the ability of purified, primary cultures of alloreactive CD4+ T
Autor:
S I Abrams, Z Brahmi
Publikováno v:
The Journal of Immunology. 140:2090-2095
We investigated the inactivation of human NK cells, a population of large granular lymphocytes (LGL), with K562, an NK-sensitive target cell (TC) and KLCL, an NK-resistant TC, but which can be lysed by NK cells via antibody (Ab)-dependent cellular cy
Publikováno v:
The Journal of Immunology. 135:4108-4113
In this study, we examined the functional status of human natural killer (NK) cells after their direct interaction with the NK-sensitive tumor target cell (TC), K562. Human peripheral blood lymphocytes depleted of adherent cells were incubated for 4