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Profiling diverse sequence tandem repeats in colorectal cancer reveals co-occurrence of microsatellite and chromosomal instability involving Chromosome 8

Autor: Hanlee P. Ji, Lan Zhao, Susan M. Grimes, Stephanie U. Greer, Carlos Suárez, Erik S. Hopmans, Alison Almeda, GiWon Shin, Hojoon Lee, Laura Miotke, Sigurdis Haraldsdottir

Publikováno v: Genome Medicine, Vol 13, Iss 1, Pp 1-18 (2021)
Genome Medicine

Colorectal carcinomas (CRCs) which have lost DNA mismatch repair display hypermutability evident in a molecular phenotype called microsatellite instability (MSI). These mismatch repair deficient tumors are thought to lack widespread genomic instabili

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b68d90ab0c2a44b6b7ab53ee66ed201
https://doaj.org/article/f712076aec7c479ebafdae1d3b8bdf16

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Akademický článek

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LMP1 association with CD63 in endosomes and secretion via exosomes limits constitutive NF-κB activation

Autor: Tineke Vendrig, Frederik J. Verweij, Ellen Cahir-McFarland, Elliott Kieff, Jaap M. Middeldorp, Thomas Wurdinger, Monique A. J. van Eijndhoven, D. Michiel Pegtel, Dirk Geerts, Rik van der Kant, Erik S. Hopmans, Jacques Neefjes

Publikováno v: The EMBO Journal. 30:2115-2129

The ubiquitous Epstein Barr virus (EBV) exploits human B‐cell development to establish a persistent infection in ∼90% of the world population. Constitutive activation of NF‐κB by the viral oncogene latent membrane protein 1 (LMP1) has an impor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::afde621791ccb3f8ed9f6aab5c76d299
https://doi.org/10.1038/emboj.2011.123

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Akademický článek

Bibliometric Analysis of Contemporary Research on the Amelioration of Saline Soils.

Autor: Zhang, Hui^1,2,3,4,5 (AUTHOR) zhangh0105@126.com, Wang, Yuancai^1,2,3 (AUTHOR) 13789381314@163.com, Liu, Lichang^1,2,4 (AUTHOR) quequebaby2021@163.com, Zhou, Jiayi^1,2,5 (AUTHOR) m19906258896@163.com, Wan, Qun^1,2,4 (AUTHOR) wanqun@jaas.ac.cn, Chen, Ji⁶ (AUTHOR) szgbz2002@163.com, Cao, Yaoyao^1,2 (AUTHOR) leigang.zh@163.com, Zhang, Leigang^1,2 (AUTHOR) fengfayun@jaas.ac.cn, Feng, Fayun^1,2 (AUTHOR) ningqi@jaas.ac.cn, Ning, Qi^1,2 (AUTHOR) yuxy@jaas.ac.cn, Yu, Xiangyang^1,2,3,4 (AUTHOR)

Publikováno v: Agronomy. Dec2024, Vol. 14 Issue 12, p2935. 16p.

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Emergence of Hemagglutinin Mutations During the Course of Influenza Infection

Autor: Amanda Kamali, Erik S. Hopmans, Susan M. Grimes, Ronald B. Moss, John Bell, Nan Zhang, Li C. Xia, Hanlee P. Ji, Mark Holodniy, Mark A. Winters, Anna Cushing

Publikováno v: Scientific Reports

Influenza remains a significant cause of disease mortality. The ongoing threat of influenza infection is partly attributable to the emergence of new mutations in the influenza genome. Among the influenza viral gene products, the hemagglutinin (HA) gl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e0371f62eba9ccaec8bf72f838d5946

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Abstract 1436: Identification of novel tumor suppressor candidates in familial cholangiocarcinoma using sequencing-based Megabase-scale haplotypes from germline and cancer genomes

Autor: Hanlee P. Ji, John Bell, Erik S. Hopmans, Billy T. Lau, Lincoln Nadauld, Laura Miotke, David A. Jones, Stephanie Greer, Christina Wood

Publikováno v: Cancer Research. 77:1436-1436

Cholangiocarcinoma (bile duct cancer) is a rare epithelial malignancy with an extremely poor prognosis characterized by a 5-year survival of less than 10%. While this tumor type can be amenable to specific combination chemotherapy regimens, it is typ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a05bb1ee567d2a9ff55028b02305d1b7
https://doi.org/10.1158/1538-7445.am2017-1436

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Multiple putative oncogenes at the chromosome 20q amplicon contribute to colorectal adenoma to carcinoma progression

Autor: Cindy Postma, Olivier Thas, Mike E. Craanen, Gerrit A. Meijer, Beatriz Carvalho, Miguel A. Cuesta, M.A. van de Wiel, Evelin Schröck, W van Criekinge, Bauke Ylstra, J. S. Terhaar sive Droste, Erik S. Hopmans, Sandra Mongera, Sharon J. Diskin, A Matthäi

Publikováno v: Gut, 58, 79-89. BMJ Publishing Group
Pinto Morais de Carvalho, B, Postma, C, Mongera, S, Hopmans, E, Diskin, S, van de Wiel, M A, van Crieckinge, W, Thas, O, Matthaï, A, Cuesta valentin, M A, Terhaar sive Droste, J S, Craanen, M, Schröck, E & Ijlstra, B 2009, ' Multiple putative oncogenes at the chromosome 20q amplicon contribute to colorectal adenoma to carcinoma progression ', Gut, vol. 58, pp. 79-89 . https://doi.org/10.1136/gut.2007.143065

Objective: This study aimed to identify the oncogenes at 20q involved in colorectal adenoma to carcinoma progression by measuring the effect of 20q gain on mRNA expression of genes in this amplicon. Methods: Segmentation of DNA copy number changes on

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fccbeee8a10601917f8bea83806ebe8c
https://research.vumc.nl/en/publications/0263cd9f-981f-4051-9a1e-220fd2246759

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