Zobrazeno 1 - 10
of 1 627
pro vyhledávání: '"S Herbert"'
Autor:
Surender Khurana, Gabrielle Grubbs, Supriya Ravichandran, Emily Cluff, JungHyun Kim, Ana I. Kuehne, Samantha Zak, John M. Dye, Julius J. Lutwama, Andrew S. Herbert
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Limited knowledge exists on the quality of polyclonal antibody responses generated following Marburg virus (MARV) infection and its evolution in survivors. In this study, we evaluate MARV proteome-wide antibody repertoire longitudinally in c
Externí odkaz:
https://doaj.org/article/9b784c44b75a49e2a60b6d1f5a8be3ea
Autor:
Hung Caohuy, Ofer Eidelman, Tinghua Chen, Ognoon Mungunsukh, Qingfeng Yang, Nathan I. Walton, Bette S. Pollard, Sara Khanal, Shannon Hentschel, Catalina Florez, Andrew S. Herbert, Harvey B. Pollard
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract SARS-CoV-2-contributes to sickness and death in COVID-19 patients partly by inducing a hyper-proinflammatory immune response in the host airway. This hyper-proinflammatory state involves activation of signaling by NFκB, and unexpectedly, EN
Externí odkaz:
https://doaj.org/article/7a2225a402c0400ca2a99fa970f2b2ac
Autor:
Olivia S. Shin, Stephanie R. Monticelli, Christy K. Hjorth, Vladlena Hornet, Michael Doyle, Dafna Abelson, Ana I. Kuehne, Albert Wang, Russell R. Bakken, Akaash K. Mishra, Marissa Middlecamp, Elizabeth Champney, Lauran Stuart, Daniel P. Maurer, Jiannan Li, Jacob Berrigan, Jennifer Barajas, Stephen Balinandi, Julius J. Lutwama, Leslie Lobel, Larry Zeitlin, Laura M. Walker, John M. Dye, Kartik Chandran, Andrew S. Herbert, Noel T. Pauli, Jason S. McLellan
Publikováno v:
Cell Reports, Vol 43, Iss 7, Pp 114502- (2024)
Summary: Crimean-Congo hemorrhagic fever virus can cause lethal disease in humans yet there are no approved medical countermeasures. Viral glycoprotein GP38, exclusive to Nairoviridae, is a target of protective antibodies and is a key antigen in prec
Externí odkaz:
https://doaj.org/article/d783005edd1a4330be69737cbfd33c17
Autor:
Ariel S Wirchnianski, Elisabeth K Nyakatura, Andrew S Herbert, Ana I Kuehne, Shawn A Abbasi, Catalina Florez, Nadia Storm, Lindsay G A McKay, Leandrew Dailey, Erin Kuang, Dafna M Abelson, Anna Z Wec, Srinjoy Chakraborti, Frederick W Holtsberg, Sergey Shulenin, Zachary A Bornholdt, M Javad Aman, Anna N Honko, Anthony Griffiths, John M Dye, Kartik Chandran, Jonathan R Lai
Publikováno v:
PLoS Pathogens, Vol 20, Iss 4, p e1012134 (2024)
Monoclonal antibodies (mAbs) are an important class of antiviral therapeutics. MAbs are highly selective, well tolerated, and have long in vivo half-life as well as the capacity to induce immune-mediated virus clearance. Their activities can be furth
Externí odkaz:
https://doaj.org/article/2302156227ee41508fe68701e955e1ae
Autor:
Megan M. Slough, Rong Li, Andrew S. Herbert, Gorka Lasso, Ana I. Kuehne, Stephanie R. Monticelli, Russell R. Bakken, Yanan Liu, Agnidipta Ghosh, Alicia M. Moreau, Xiankun Zeng, Félix A. Rey, Pablo Guardado-Calvo, Steven C. Almo, John M. Dye, Rohit K. Jangra, Zhongde Wang, Kartik Chandran
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Andes virus (ANDV) and Sin Nombre virus (SNV) are the etiologic agents of severe hantavirus cardiopulmonary syndrome (HCPS) in the Americas for which no FDA-approved countermeasures are available. Protocadherin-1 (PCDH1), a cadherin-superfam
Externí odkaz:
https://doaj.org/article/f3b912d0b0034e259a6b83f7a5d19e50
Autor:
Kevin M. Taylor, MD, Keersten M. Ricks, PhD, Paul A. Kuehnert, MS, Angelia A. Eick-Cost, PhD, Mark R. Scheckelhoff, PhD, Andrew R. Wiesen, MD, Tamara L. Clements, MS, Zheng Hu, MS, Samantha E. Zak, MS, Scott P. Olschner, BS, Andrew S. Herbert, PhD, Sara L. Bazaco, PhD, Kathleen E. Creppage, DrPH, Michael T. Fan, PhD, Jose L. Sanchez, MD
Publikováno v:
AJPM Focus, Vol 2, Iss 4, Pp 100141- (2023)
Introduction: Reported confirmed cases represent a small portion of overall true cases for many infectious diseases. The undercounting of true cases can be considerable when a significant portion of infected individuals are asymptomatic or minimally
Externí odkaz:
https://doaj.org/article/46f890f1f6904f0f8de6f3960c5f05ce
Autor:
Jason Nan, Matthew S. Herbert, Suzanna Purpura, Andrea N. Henneken, Dhakshin Ramanathan, Jyoti Mishra
Publikováno v:
Sensors, Vol 24, Iss 8, p 2640 (2024)
Healthcare professionals are known to suffer from workplace stress and burnout, which can negatively affect their empathy for patients and quality of care. While existing research has identified factors associated with wellbeing and empathy in health
Externí odkaz:
https://doaj.org/article/bd08342c4b5f47fd8c1275e0512f53f9
Autor:
Nasser Al‐Qattan, Gregory S. Herbert, Howard J. Spero, Sean McCarthy, Ryan McGeady, Ran Tao, Anne‐Marie Power
Publikováno v:
AGU Advances, Vol 4, Iss 4, Pp n/a-n/a (2023)
Abstract A flaperon belonging to Malaysian Airlines flight MH370 washed ashore on Réunion Island covered with the barnacle Lepas anatifera in July 2015, more than a year after the plane's disappearance. Here, we report the first high‐precision δ1
Externí odkaz:
https://doaj.org/article/af351d28e8eb4f6cb72d5d61047d3b1c
Publikováno v:
BMC Pregnancy and Childbirth, Vol 22, Iss 1, Pp 1-10 (2022)
Abstract Background Pregnancy is an important time for women’s mental health and marks the foundations of the emerging bond between mother and baby. This study aimed to investigate the role of pregnancy acceptability and intendedness in maternal me
Externí odkaz:
https://doaj.org/article/b04d8bce2935498ab3bdeeb62360ad6f
Autor:
Elizabeth E. Zumbrun, Samantha E. Zak, Eric D. Lee, Philip A. Bowling, Sara I. Ruiz, Xiankun Zeng, Jeffrey W. Koehler, Korey L. Delp, Russel R. Bakken, Shannon S. Hentschel, Holly A. Bloomfield, Keersten M. Ricks, Tamara L. Clements, April M. Babka, John M. Dye, Andrew S. Herbert
Publikováno v:
Viruses, Vol 15, Iss 12, p 2341 (2023)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of the worldwide COVID-19 pandemic. Animal models are extremely helpful for testing vaccines and therapeutics and for dissecting the viral and host factors that contr
Externí odkaz:
https://doaj.org/article/bd56c47970434e62b1faeb69e1895bd8