Zobrazeno 1 - 10
of 224
pro vyhledávání: '"S Hain"'
Autor:
J. Gutt, S. Arndt, D. K. A. Barnes, H. Bornemann, T. Brey, O. Eisen, H. Flores, H. Griffiths, C. Haas, S. Hain, T. Hattermann, C. Held, M. Hoppema, E. Isla, M. Janout, C. Le Bohec, H. Link, F. C. Mark, S. Moreau, S. Trimborn, I. van Opzeeland, H.-O. Pörtner, F. Schaafsma, K. Teschke, S. Tippenhauer, A. Van de Putte, M. Wege, D. Zitterbart, D. Piepenburg
Publikováno v:
Biogeosciences, Vol 19, Pp 5313-5342 (2022)
Systematic long-term studies on ecosystem dynamics are largely lacking from the East Antarctic Southern Ocean, although it is well recognized that they are indispensable to identify the ecological impacts and risks of environmental change. Here, we p
Externí odkaz:
https://doaj.org/article/abd330f9342c4580bf6cf8756fa5bff1
Autor:
Isabella Slaby, Heather S. Hain, Debra Abrams, Frank D. Mentch, Joseph T. Glessner, Patrick M. A. Sleiman, Hakon Hakonarson
Publikováno v:
Journal of Neurodevelopmental Disorders, Vol 14, Iss 1, Pp 1-9 (2022)
Abstract Background In over half of pediatric cases, ADHD presents with comorbidities, and often, it is unclear whether the symptoms causing impairment are due to the comorbidity or the underlying ADHD. Comorbid conditions increase the likelihood for
Externí odkaz:
https://doaj.org/article/1b1e8cb345094bce9ed6f82755d1f219
Autor:
James P. Cwick, Jonathan E. Owen, Irina Kochetkova, Kyle S. Hain, Nick Van Horssen, Matthew P. Taylor
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 3 (2022)
ABSTRACT Superinfection exclusion (SIE) is a phenomenon in which a primary viral infection interferes with secondary viral infections within that same cell. Although SIE has been observed across many viruses, it has remained relatively understudied.
Externí odkaz:
https://doaj.org/article/8838d300df784c7e9cbae6c8ef00805f
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract CLEC16A is implicated in multiple autoimmune diseases. We generated an inducible whole-body knockout (KO), Clec16a ΔUBC mice to address the role of CLEC16A loss of function. KO mice exhibited loss of adipose tissue and severe weight loss in
Externí odkaz:
https://doaj.org/article/cda559f7568a4bf68d7b2e7e1326d8b2
Autor:
Heather S. Hain, Rahul Pandey, Marina Bakay, Bryan P. Strenkowski, Danielle Harrington, Micah Romer, William W. Motley, Jian Li, Eunjoo Lancaster, Lindsay Roth, Judith B. Grinspan, Steven S. Scherer, Hakon Hakonarson
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract CLEC16A has been shown to play a role in autophagy/mitophagy processes. Additionally, genetic variants in CLEC16A have been implicated in multiple autoimmune diseases. We generated an inducible whole-body knockout, Clec16a ΔUBC mice, to inv
Externí odkaz:
https://doaj.org/article/9b104a7aa9a7427988082d3423e2cc80
Autor:
Xueming Yao, Joseph T. Glessner, Junyi Li, Xiaohui Qi, Xiaoyuan Hou, Chonggui Zhu, Xiaoge Li, Michael E. March, Liu Yang, Frank D. Mentch, Heather S. Hain, Xinyi Meng, Qianghua Xia, Hakon Hakonarson, Jin Li
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Neuropsychiatric disorders, such as autism spectrum disorder (ASD), attention deficit hyperactivity disorder (ADHD), schizophrenia (SCZ), bipolar disorder (BIP), and major depressive disorder (MDD) share common clinical presentations, sugges
Externí odkaz:
https://doaj.org/article/04d58022a0c14684b61044691d399e6b
Autor:
Sydney R. Willhite, MD, Adam C. Warner, MD, Julius S. Hain, BS, BA, Margaret C. Nickerson, BS, David A. Peterson, MD, Duangnapa S. Cuddy, DO
Publikováno v:
Journal of Vascular Surgery Cases and Innovative Techniques, Vol 8, Iss 3, Pp 494-495 (2022)
The increasing use of endovascular aneurysm repair to treat abdominal aortic aneurysms has mandated solutions to the limitations of this operation, including the requirement for additional procedures. A 64-year-old man had presented with symptomatic
Externí odkaz:
https://doaj.org/article/e0a71ded15d944eab24463da287c6155
Autor:
Rahul Pandey, Marina Bakay, Heather S. Hain, Bryan Strenkowski, Anastasiya Yermakova, Jake A. Kushner, Jordan S. Orange, Hakon Hakonarson
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
CLEC16A locus polymorphisms have been associated with several autoimmune diseases. We overexpressed CLEC16A in YTS natural killer (NK) cells and observed reduced NK cell cytotoxicity and IFN-γ release, delayed dendritic cell (DC) maturation, decreas
Externí odkaz:
https://doaj.org/article/ddd11a6211d44fbb8dc08527d72c76c8
Autor:
Emma K. Loveday, Kyle S. Hain, Irina Kochetkova, Jodi F. Hedges, Amanda Robison, Deann T. Snyder, Susan K. Brumfield, Mark J. Young, Mark A. Jutila, Connie B. Chang, Matthew P. Taylor
Publikováno v:
Viruses, Vol 13, Iss 4, p 562 (2021)
The risk posed by Severe Acute Respiratory Syndrome Coronavirus -2 (SARS-CoV-2) dictates that live-virus research is conducted in a biosafety level 3 (BSL3) facility. Working with SARS-CoV-2 at lower biosafety levels can expedite research yet require
Externí odkaz:
https://doaj.org/article/795ea567f91f4f81a5777daca8b1f583
Autor:
Gijs van Ingen, Jin Li, André Goedegebure, Rahul Pandey, Yun Rose Li, Michael E. March, Vincent W. V. Jaddoe, Marina Bakay, Frank D. Mentch, Kelly Thomas, Zhi Wei, Xiao Chang, Heather S. Hain, André G. Uitterlinden, Henriette A. Moll, Cornelia M. van Duijn, Fernando Rivadeneira, Hein Raat, Robert J. Baatenburg de Jong, Patrick M. Sleiman, Marc P. van der Schroeff, Hakon Hakonarson
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-7 (2016)
Acute otitis media (AOM) is an acute infection of middle ear mucosa and among the most common pediatric diseases. Here, the authors performed a genome-wide association study to link a variant in the FNDC1 locus on 6q25.3 and differential methylation
Externí odkaz:
https://doaj.org/article/5e841bd590864ecca71796318ebd7c9f