Zobrazeno 1 - 10
of 56
pro vyhledávání: '"S H Phan"'
Publikováno v:
Current Medicinal Chemistry. 16:1400-1417
Idiopathic Pulmonary Fibrosis (IPF) is characterized by injury and loss of lung epithelial cells, accumulation of fibroblasts/myofibroblasts and abnormal remodeling of the lung parenchyma. The prognosis for IPF patients is poor and current therapies
Publikováno v:
The Journal of Immunology. 158:1392-1399
IL-1 is important in regulating lung inflammation and potentially fibrosis as well. To clarify the role of this cytokine vis-à-vis changes in lung fibroblast phenotype in pulmonary fibrosis, the effects of IL-1beta on isolated lung fibroblasts were
Publikováno v:
The Journal of Immunology. 158:954-959
Despite abundant evidence documenting the importance of TNF-alpha in the pathogenesis of pulmonary fibrosis, its actual role has not been fully elucidated. Recent observations also indicate that eosinophils found in fibrotic lung express elevated lev
Publikováno v:
The Journal of Immunology. 153:4733-4741
Recent studies indicate that monocyte chemoattractant protein-1 (MCP-1) may play an important role in pulmonary inflammation. In vitro studies show that a number of cell types are capable of producing MCP-1. In this study, MCP-1 expression in lungs o
Publikováno v:
The Journal of Immunology. 149:103-106
Recent studies suggest that transforming growth factor-beta (TGF-beta) production is up-regulated at sites of tissue injury, inflammation and repair, or fibrosis. Endothelial cells represent a potentially important in vivo source of TGF-beta; however
Publikováno v:
Current medicinal chemistry. 16(11)
Idiopathic Pulmonary Fibrosis (IPF) is characterized by injury and loss of lung epithelial cells, accumulation of fibroblasts/myofibroblasts and abnormal remodeling of the lung parenchyma. The prognosis for IPF patients is poor and current therapies
Autor:
S H Phan, Mehrnaz Gharaee-Kermani
Publikováno v:
Current pharmaceutical design. 11(30)
Pulmonary fibrosis is characterized by lung inflammation and abnormal tissue repair, resulting in the replacement of normal functional tissue with an abnormal accumulation of fibroblasts and deposition of collagen in the lung. This process involves c
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Autor:
J, Varani, R L, Warner, M, Gharaee-Kermani, S H, Phan, S, Kang, J H, Chung, Z Q, Wang, S C, Datta, G J, Fisher, J J, Voorhees
Publikováno v:
The Journal of investigative dermatology. 114(3)
Damage to human skin due to ultraviolet light from the sun (photoaging) and damage occurring as a consequence of the passage of time (chronologic or natural aging) are considered to be distinct entities. Photoaging is caused in part by damage to skin
Publikováno v:
Current topics in pathology. Ergebnisse der Pathologie. 93