Zobrazeno 1 - 10
of 66
pro vyhledávání: '"S H Golub"'
Publikováno v:
Interleukin-2 and Killer Cells in Cancer ISBN: 9781351073790
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be9c56dceab7af649489c0003eb34910
https://doi.org/10.1201/9781351073790-8
https://doi.org/10.1201/9781351073790-8
Publikováno v:
Lymphokine and cytokine research. 13(6)
Both the CD56bright and CD56dim NK cell subpopulation mediate non-major histocompatibility complex-restricted cytolysis of NK-sensitive tumor cell lines, and IL-2-dependent augmentation of cytolysis and proliferation of CD56bright and CD56dim NK cell
Publikováno v:
Scandinavian journal of immunology. 38(2)
TNF-alpha at 50-100 U/ml synergizes with IL-2 in enhancing LAK activity and IL-6 production in low-dose IL-2 (1-10 U/ml) culture of human PBL. High-dose TNF-alpha (> or = 200 U/ml) has less effect and even sometimes resulted in lowering of both LAK a
Publikováno v:
Natural immunity. 12(4-5)
Natural killer (NK) cells and interleukin-2 activated NK cells, termed lymphokine-activated killer (LAK) cells, can lyse tumor cells without restriction by the MHC complex. The cytotoxic activity of these cells is subject to regulation by nonlymphoid
Publikováno v:
The Journal of biological chemistry. 267(31)
The 1311-base pair human tumor necrosis factor (TNF) alpha promoter region was fused to the luciferase (Luc) reporter gene and studied in a transient transfection system in three TNF producing cell lines, the U937 macrophage cell line, the MLA 144 T
Publikováno v:
Journal of leukocyte biology. 51(4)
Natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxic functions can be strongly augmented by the iron-carrier protein lactoferrin (LF). LF significantly enhances NK and LAK activities when added at the beginning of NK or LAK cytoto
Publikováno v:
Journal of biological response modifiers. 9(1)
Patients with metastatic solid tumors were treated with six escalating doses of weekly intralymphatically injected recombinant interleukin 2 (i.l. IL-2). Nine patients completed the treatment and were evaluated for immunologic features of their perip
Autor:
R U de Fries, S H Golub
Publikováno v:
The Journal of Immunology. 140:3686-3693
IFN-gamma has been shown to reduce the sensitivity of tumor cells to lysis by NK cells. The close relationship between NK cells and lymphokine-activated killer (LAK) cells has prompted us to investigate whether IFN-gamma pre-treatment also affects th