Clinical effectiveness

Autor: D. J. M. McGhee, P. L. Royle, C. E. Counsell, A. Abbas, P. Sethi, L. Manku, A. Narayan, K. Clegg, A. Bardai, S. H. M. Brown, U. Hafeez, A. H. Abdelhafiz, A. McGovern, A. Breckenridge, P. Seenan, A. Samani, S. Das, S. Khan, A. J. Puffett, J. Morgan, G. Ross, A. Cantlay, N. Khan, A. Bhalla, M. Sweeting, C. A. M. D. Nimmo, J. Fleet, C. Igbedioh, D. Harari, C. L. Downey, C. Handforth, C. Stothard, A. Cracknell, C. Barnes, L. Shaw, L. Bainbridge, L. Crabtree, T. Clark, S. Root, E. Aitken, K. Haroon, M. Sudlow, K. Hanley, S. Welsh, E. Hill, A. Falconer, H. Miller, B. Martin, E. Tidy, S. Pendlebury, S. Thompson, E. Burnett, H. Taylor, J. Lonan, B. Adler, J. McCallion, E. Sykes, R. Bancroft, E. S. Tullo, T. J. Young, E. Clift, B. Flavin, H. C. Roberts, A. A. Sayer, G. Belludi, S. Aithal, A. Verma, I. Singh, M. Barne, I. Wilkinson, R. Sakoane, N. Singh, M. Cottee, T. S. Irani, O. Martinovic, A. J. J. Abdulla, J. Riglin, J. Husk, D. Lowe, J. Treml, J. N. Vasilakis, A. Buttery, J. Reid, P. Healy, J. Grant-Casey, K. Pendry, J. Richards, A. Singh, D. Jarrett, J. Hewitt, J. Slevin, G. Barwell, J. Youde, C. Kennedy, R. Romero-Ortuno, D. O'Shea, D. Robinson, R. A. Kenny, J. O'Connell, J. D. Topp, K. Warburton, L. Simpson, K. Bryce, S. Suntharalingam, K. Grosser, A. D'Silva, L. Southern, C. Bielawski, L. Cook, G. M. Sutton, L. Flanagan, A. Storr, L. Charlton, S. Kerr, L. Robinson, F. Shaw, L. K. Finch, N. Weerasuriya, M. Walker, O. Sahota, P. Logan, F. Brown, F. Rossiter, M. Baxter, E. Mucci, A. Brown, S. H. D. Jackson, N. de Savary, S. Hasan, H. Jones, J. Birrell, J. Hockley, N. Hensey, R. Meiring, N. Athavale, J. Simms, S. Brown, A. West, P. Diem, R. Davies, R. Kings, H. Coleman, D. Stevens, C. Campbell, S. Hope, A. Morris, T. Ong, R. Harwood, D. Dasgupta, S. Mitchell, V. Dimmock, F. Collin, E. Wood, V. Green, N. Hendrickse-Welsh, J. Eccles, J. Beezer, M. Garside, J. Baxter

Publikováno v: Age and Ageing. 42:ii5-ii16

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::413433bda67d980e2090eb88c7d92908
https://doi.org/10.1093/ageing/aft016

The bioavailability and disposition of 1-(beta-D-arabinofuranosyl)-5-(1- propynyl)uracil (882C87), a potent, new anti-varicella zoster virus agent

Autor: D. R. Lee, S. H. D. Jackson, J Posner, R. Wootton, R. W. Peck

Publikováno v: British Journal of Clinical Pharmacology. 39:143-149

1. The bioavailability and disposition of 882C87, an anti-varicella zoster virus (VZV) agent, have been investigated in healthy young and elderly volunteers. 2. The mean bioavailability of a 200 mg tablet was 21.1% in the young (range 13.3-33.0%, n =

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ae043bf2dbd3e7e049541f7859e9355
https://doi.org/10.1111/j.1365-2125.1995.tb04421.x

Clinical Trials in Elderly Patients

Autor: S. H. D. Jackson

Publikováno v: Ernst Schering Research Foundation Workshop ISBN: 9783540278672

The increasing size of the elderly population means that both the relative and absolute numbers of prescriptions for elderly patients are increasing. Depending on the age group, between 60% and 80% of elderly people are taking medication, and between

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a148e9bb5dac6ace0c1b1fa231ba4dbd
https://doi.org/10.1007/978-3-540-49529-1_7

National clinical sentinel audit of evidence-based prescribing for older people

Autor: G M, Batty, R L, Grant, R, Aggarwal, D, Lowe, J M, Potter, M G, Pearson, S H D, Jackson

Publikováno v: Journal of evaluation in clinical practice. 10(2)

To audit the performance of hospitals in evidence-based prescribing.All hospitals in England were invited to participate. The audit was completed in 62 hospitals.Prescribing and clinical data were collected on 100 consecutive medical inpatients aged/

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6e94fa73c1f614a49f83d5ef23c75e77
https://pubmed.ncbi.nlm.nih.gov/15189392

Age-related changes in pharmacokinetics and pharmacodynamics: basic principles and practical applications

Autor: A A, Mangoni, S H D, Jackson

Publikováno v: British journal of clinical pharmacology. 57(1)

Advancing age is characterized by impairment in the function of the many regulatory processes that provide functional integration between cells and organs. Therefore, there may be a failure to maintain homeostasis under conditions of physiological st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::38ef0dd3a079622e65992f312e356ed4
https://pubmed.ncbi.nlm.nih.gov/14678335