Výsledky vyhledávání - "S H, Zuckerman"

Akademický článek

Inhibition of cholesteryl ester transfer protein in normocholesterolemic and hypercholesterolemic hamsters: effects on HDL subspecies, quantity, and apolipoprotein distribution.

Autor: G F Evans, W R Bensch, L D Apelgren, D Bailey, R F Kauffman, T F Bumol, S H Zuckerman

Publikováno v: Journal of Lipid Research, Vol 35, Iss 9, Pp 1634-1645 (1994)

The effects of cholesteryl ester transfer protein (CETP) inhibition on the serum lipoprotein profile in both normocholesterolemic and hypercholesterolemic hamsters has been determined following subcutaneous injection of 12.5 mg/kg of the CETP neutral

Externí odkaz: https://doaj.org/article/8f11578b54454efeb82071934229f017

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Glucocorticoid-mediated inhibition of neutrophil emigration in an endotoxin-induced rat pulmonary inflammation model occurs without an effect on airways MIP-2 levels

Autor: Eoin C. O'Leary, S H Zuckerman

Publikováno v: American Journal of Respiratory Cell and Molecular Biology. 16:267-274

In an intratracheal endotoxin lipopolysaccharide (LPS) challenge model of acute lung injury, we recently reported that while dexamethasone (DEX) at 2 to 4 mg/kg reduced neutrophil (PMN) emigration into the airways, bronchoalveolar lavage (BAL) fluid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c0877e24a2c3e420da889e3a10949a1
https://doi.org/10.1165/ajrcmb.16.3.9070611

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In vivo inhibition of lipopolysaccharide-induced lethality and tumor necrosis factor synthesis by Rhodobacter sphaeroides diphosphoryl lipid A is dependent on corticosterone induction

Autor: S H Zuckerman, N Qureshi

Publikováno v: Infection and Immunity. 60:2581-2587

Diphosphoryl lipid A from the lipopolysaccharide (LPS) of Rhodobacter sphaeroides (Rs-DPLA) has been demonstrated to block in mice and guinea pigs the increase in the serum tumor necrosis factor (TNF) response induced by highly purified deep rough ch

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2faafdb4ba8c5661782a6c1b093c8875
https://doi.org/10.1128/iai.60.7.2581-2587.1992

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Inhibition of glycinamide ribonucleotide formyltransferase results in selective inhibition of macrophage cytokine secretion in vitro and in vivo efficacy in rat adjuvant arthritis

Autor: S, Chintalacharuvu, G F, Evans, C, Shih, H U, Bryant, G E, Sandusky, S H, Zuckerman

Publikováno v: Clinical and experimental rheumatology. 23(4)

To determine the effects of a glycinamide ribonucleotide formyltransferase (GARFT) inhibitor on macrophage inflammatory processes and in vivo in rat adjuvant arthritis.GARFT inhibitors, LY309886 (6S-2',5'-thienyl-5, 10-dideazatetrahydrofolic acid) an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d07bc409407397cc50c6d7e742299bea
https://pubmed.ncbi.nlm.nih.gov/16095109

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TGF-beta increases cholesterol efflux and ABC-1 expression in macrophage-derived foam cells: opposing the effects of IFN-gamma

Autor: C G, Panousis, G, Evans, S H, Zuckerman

Publikováno v: Journal of lipid research. 42(5)

The regulation of ATP-binding cassette transporter 1 (ABC-1) expression by cytokines present within the microenvironment of the atheroma may play an important role in determining the impact of reverse cholesterol transport on the atherosclerotic lesi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2b8484e85e7c7f92bbbee7076f33271c
https://pubmed.ncbi.nlm.nih.gov/11352993

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The effect of gamma-interferon to inhibit macrophage-high density lipoprotein interactions is reversed by 15-deoxy-delta12,14-prostaglandin J2

Autor: S H, Zuckerman, C, Panousis, J, Mizrahi, G, Evans

Publikováno v: Lipids. 35(11)

Macrophage activation has been recognized as playing a central role in chronic inflammatory diseases in general and, more specifically, in the vascular wall during the progression of atherosclerotic lesions. Macrophage-activating factors present with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2b5ee7fd87bb10590e61c480960cfd9c
https://pubmed.ncbi.nlm.nih.gov/11132183

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Regulation of cholesterol distribution in macrophage-derived foam cells by interferon-gamma

Autor: C G, Panousis, S H, Zuckerman

Publikováno v: Journal of lipid research. 41(1)

The Th1-derived cytokine gamma interferon, IFN-gamma, is present within the microenvironment of an atheromatous lesion and likely contributes to lesion progression through macrophage activation. While the inflammatory effects of IFN-gamma are well kn

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bf0ac521c43aa54edd85a37ce5d0433d
https://pubmed.ncbi.nlm.nih.gov/10627504

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Expression of CD54 (intercellular adhesion molecule-1) and the beta 1 integrin CD29 is modulated by a cyclic AMP dependent pathway in activated primary rat microglial cell cultures

Autor: S H, Zuckerman, J, Gustin, G F, Evans

Publikováno v: Inflammation. 22(1)

Microglial cell activation plays a central role in acute and chronic inflammatory processes associated with neurodegeneration. As macrophage activation is generally associated with the up-regulation of specific surface antigens, the expression of CD5

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::80b318968c0033a7aad0826bcf7ae870
https://pubmed.ncbi.nlm.nih.gov/9484653

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In vivo dexamethasone effects on neutrophil effector functions in a rat model of acute lung injury

Autor: E C, O'Leary, G F, Evans, S H, Zuckerman

Publikováno v: Inflammation. 21(6)

Glucocorticoids, while potent antiinflammatory agents, have not been proven to be efficacious in Acute Respiratory Distress Syndrome, ARDS. Previous studies from this laboratory have reported that dexamethasone pretreatment of rats resulted in a 40-6

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::305150bbc52341814cade2a5d3ac3d3c
https://pubmed.ncbi.nlm.nih.gov/9429907

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