Zobrazeno 1 - 10
of 70
pro vyhledávání: '"S H, Zorn"'
Autor:
J A, Lowe, S E, Drozda, R M, Snider, K P, Longo, S H, Zorn, J, Morrone, E R, Jackson, S, McLean, D K, Bryce, J, Bordner
Publikováno v:
Journal of Medicinal Chemistry. 35:2591-2600
We describe the structure-activity relationship development of a series of quinuclidines which culminated in the first potent, selective, nonpeptide substance P (SP) antagonist, (2S,3S)-cis-2-(diphenylmethyl)-N-[(2-methoxy-phenyl)methyl]-1- azabicycl
Autor:
D E, Casey, S H, Zorn
Publikováno v:
The Journal of clinical psychiatry. 62
In general, antipsychotic agents have diverse actions on a wide range of neurotransmitter systems. Data strongly suggest that a number of these systems may play a role in the regulation of body weight. In addition to having very distinct pharmacologi
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 281(1)
Panicogenic effects in humans of the selective cholecystokinin (CCK(B)) receptor agonist, cholecystokinin tetrapeptide (CCK4), have been reported to correlate with increases in heart rate (HR) and mean arterial pressure (MAP). Previous investigators
Autor:
T F, Seeger, P A, Seymour, A W, Schmidt, S H, Zorn, D W, Schulz, L A, Lebel, S, McLean, V, Guanowsky, H R, Howard, J A, Lowe
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 275(1)
Ziprasidone (CP-88,059) is a combined 5-HT (serotonin) and dopamine receptor antagonist which exhibits potent effects in preclinical assays predictive of antipsychotic activity. Whereas the compound is a dopamine antagonist in vitro and in vivo, its
Autor:
Miaomei Yu, Mi Shen, Daiyue Chen, Yan Li, Qiang Zhou, Chunyan Deng, Xinyang Zhou, Qi Zhang, Qianru He, Hongkui Wang, Meng Cong, Haiyan Shi, Xiaosong Gu, Songlin Zhou, Fei Ding
Publikováno v:
Bioactive Materials; Oct2024, Vol. 40, p378-395, 18p
Autor:
Wei, Jun‐Sheng1 (AUTHOR), Xu, Zi‐Yu1 (AUTHOR), Wei, Yin2 (AUTHOR) weiyin@sioc.ac.cn, Shi, Min1,2 (AUTHOR) mshi@mail.sioc.ac.cn
Publikováno v:
Advanced Synthesis & Catalysis. 6/13/2023, Vol. 365 Issue 11, p1864-1870. 7p.
Autor:
S H, Zorn, R S, Duman, A, Giachetti, R, Micheletti, E, Giraldo, P, Krogsgaard-Larsen, S J, Enna
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 242(1)
Previous reports have suggested that the ethyl ester of (R)-nipecotic acid ethyl ester [(R)-NAEE] displays cholinomimetic properties in vivo. The present study was undertaken to characterize more fully this action by examining the effects of (R)-NAEE
Autor:
Sullivan, Jeremy M., Bagnell, Anna M., Alevy, Jonathan, Avila, Elvia Mena, Mihaljević, Ljubica, Saavedra-Rivera, Pamela C., Kong, Lingling, Huh, Jennifer S., McCray, Brett A., Aisenberg, William H., Zuberi, Aamir R., Bogdanik, Laurent, Lutz, Cathleen M., Qiu, Zhaozhu, Quinlan, Katharina A., Searson, Peter C., Sumner, Charlotte J.
Publikováno v:
Science Translational Medicine; 5/22/2024, Vol. 16 Issue 748, p1-14, 14p
Publikováno v:
Journal of The Electrochemical Society; May2024, Vol. 171 Issue 5, p1-15, 15p
Autor:
Kolesnik, Irina A., Potkin, Vladimir I., Grigoriev, Mikhail S., Novikov, Anton P., Gomila, Rosa M., Podrezova, Alexandra G., Brazhkin, Vadim V., Zubkov, Fedor I., Frontera, Antonio
Publikováno v:
CrystEngComm; 4/7/2023, Vol. 25 Issue 13, p1976-1985, 10p