Zobrazeno 1 - 10
of 16
pro vyhledávání: '"S H, Pollock"'
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 280(2)
4-Phenyl-3-butenoic acid (PBA) has been shown in vitro to be a turnover-dependent inactivator of peptidylglycine alpha-monooxygenase (PAM), the rate-limiting enzyme involved in the formation of amidated neuropeptides from their glycine-extended precu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b3e6f4e3a1ff93a92db0bd918235feee
https://pubmed.ncbi.nlm.nih.gov/9023299
https://pubmed.ncbi.nlm.nih.gov/9023299
Autor:
S H, Pollock, M I, Reichbaum, J C, Colbert, P A, Husain, J M, Holbrook, A A, Ogonowski, J S, Khlief, S W, May
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 265(3)
We have reported previously that phenyl-2-aminoethyl sulfide and its derivatives are excellent substrates for dopamine-beta-monooxygenase and produce an antihypertensive effect in spontaneously hypertensive rats after i.p. administration. In the stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8414902ac23efc233ea0df81e49340cd
https://pubmed.ncbi.nlm.nih.gov/8509996
https://pubmed.ncbi.nlm.nih.gov/8509996
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 258(1)
Diabetic patients often have a kidney or pancreas allograft requiring cyclosporine A (CsA) to prevent transplant rejection. These patients usually take p.o. hypoglycemic agents to control their diabetes. Because of the reported adverse effects of CsA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6bf0df2ac7be65ecbc4f779faaf27d48
https://pubmed.ncbi.nlm.nih.gov/1906541
https://pubmed.ncbi.nlm.nih.gov/1906541
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 17(6)
Cyclosporine A (CsA) has been shown to be effective in patients with rheumatoid arthritis and to prevent the development and improve the symptoms of adjuvant-induced arthritis in rats. Since abnormal drug disposition has been reported in inflammatory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::10fcbfb0366489b7f1cd990523a61e96
https://pubmed.ncbi.nlm.nih.gov/2575493
https://pubmed.ncbi.nlm.nih.gov/2575493
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 16(1)
Cyclosporine (CsA) is used to prevent rejection of transplanted organs. It is extensively metabolized in the liver by the mixed function oxidase enzyme system by demethylation and hydroxylation. Since cimetidine is a widely prescribed H2 antagonist d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dae33bcee9f4765c2581b305e957482a
https://pubmed.ncbi.nlm.nih.gov/2894956
https://pubmed.ncbi.nlm.nih.gov/2894956
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 4(1)
The enzyme systems involved in the reduction of the narcotic antagonists, naloxone and naltrexone, were studied from the liver of chicken and rabbit. These secies were chosen because the relative amounts of diastereoisomeric products formed by enzyma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::108cc6c3f63ebd8d4356829d2d84344b
https://pubmed.ncbi.nlm.nih.gov/56258
https://pubmed.ncbi.nlm.nih.gov/56258
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 16(2)
Cyclosporine (CsA), an immunosuppressant, is used widely to prevent rejection of transplanted organs. It is extensively metabolized in the liver by hydroxylation and demethylation. Since phenytoin is used extensively post-transplant as an anti-convul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ffe772f8cc3d7e58486049fee1174238
https://pubmed.ncbi.nlm.nih.gov/2898343
https://pubmed.ncbi.nlm.nih.gov/2898343
Publikováno v:
Chemischer Informationsdienst. 16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5bb8821a0f5fb9a626787a8153b68c6
https://doi.org/10.1002/chin.198509180
https://doi.org/10.1002/chin.198509180
Publikováno v:
Archives internationales de pharmacodynamie et de therapie. 296
In earlier work we have demonstrated that a novel series of phenylethylamine analogs (phenyl-2-aminoethyl sulfides) cause a potent antihypertensive effect in spontaneously hypertensive rats. In addition, we have shown in vitro that these compounds ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f857900753eef82dd435dccb7255f379
https://pubmed.ncbi.nlm.nih.gov/3240025
https://pubmed.ncbi.nlm.nih.gov/3240025
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 16(5)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::286c546b7dd251ad470e28176f2b603a
https://pubmed.ncbi.nlm.nih.gov/2906606
https://pubmed.ncbi.nlm.nih.gov/2906606