Zobrazeno 1 - 10
of 54
pro vyhledávání: '"S H, Nellis"'
Publikováno v:
Journal of the American College of Cardiology. 26:815-825
Objectives This study sought to evaluate the functional and metabolic consequences of imposing a chronic external coronary stenosis around the left anterior descending coronary artery for 4 days in an intact pig model. Background A clinical condition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02d5cddb9ee44d874cb8dfe6da668696
https://doi.org/10.1016/0735-1097(95)00223-q
https://doi.org/10.1016/0735-1097(95)00223-q
Autor:
A. James Liedtke, T. L. Mulnix, Adrian D. Nunn, Charles K. Stone, Robert J. Nickles, Bruce L. Kuczynski, B. Renstrom, William L. Rumsey, S. H. Nellis
Publikováno v:
Circulation. 92:1246-1253
Background A new nitroimidazole complex, 99m Tc-propylene amine oxime-1,2-nitroimidazole (BMS-181321), has been developed to allow the positive imaging of hypoxic myocardium by standard gamma camera techniques. Methods and Results To determine the my
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7507d21da633562326edc5366bcbce61
https://doi.org/10.1161/01.cir.92.5.1246
https://doi.org/10.1161/01.cir.92.5.1246
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 269:H246-H253
The purpose of this report was to directly measure the influence of antecedent ischemia or repetitive ischemia on subsequent rates of intermediary metabolism, specifically exogenous glucose utilization and fatty acid oxidation, with the use of myocar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da6fb774551831df583d2d058a10572d
https://doi.org/10.1152/ajpheart.1995.269.1.h246
https://doi.org/10.1152/ajpheart.1995.269.1.h246
Myocardial function and metabolism in pig hearts after relief from chronic partial coronary stenosis
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 267:H1312-H1319
Metabolic behavior was compared during acute extracorporeal reperfusion after removal of a chronic 4-day partial coronary stenosis in eight pig hearts (RCS group) and during comparable extracorporeal perfusion in seven chronically prepared hearts (Sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a948b68fc9f59de8dece2316cf81630
https://doi.org/10.1152/ajpheart.1994.267.4.h1312
https://doi.org/10.1152/ajpheart.1994.267.4.h1312
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 265:H1614-H1622
The purpose of these studies was to evaluate metabolic behavior in a 4-day reperfusion model in pigs after induction of subendocardial infarction. Two groups of swine [sham and intervention (Int) groups, n = 7) and 10 hearts per group, respectively]
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f61fcb78d188d43a53eb2b81bae264d4
https://doi.org/10.1152/ajpheart.1993.265.5.h1614
https://doi.org/10.1152/ajpheart.1993.265.5.h1614
Publikováno v:
Circulation Research. 71:689-700
Studies were conducted in extracorporeally perfused, intact, working pig hearts to determine whether, in heart muscle, trace-labeled deoxyglucose serves as an accurate marker of glycolytic flux in reperfusion after exposures to mild to moderate regio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca57982eea505472d4f0ed80d451cd00
https://doi.org/10.1161/01.res.71.3.689
https://doi.org/10.1161/01.res.71.3.689
Distribution of carbon flux within fatty acid utilization during myocardial ischemia and reperfusion
Publikováno v:
Circulation Research. 69:779-790
Twenty-nine intact, working pig hearts were extracorporeally perfused and divided into two study groups (16 Aerobic and 13 Ischemic/Reflow hearts). Step function, equilibrium labeling with [14C]palmitate was used to develop uptake and washout curves
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12c749ac6d83b5301fe1df291368d9aa
https://doi.org/10.1161/01.res.69.3.779
https://doi.org/10.1161/01.res.69.3.779
Publikováno v:
Cardiovascular Drugs and Therapy. 5:37-43
The purpose of this report is to describe the contribution of propionate as an adjunct source of oxidative metabolism in aerobic myocardium. In the first series of studies, six groups of isolated working rat hearts (n=6–8 per group) were perfused f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1968b6e8b082a6905241b20c83eb4a6
https://doi.org/10.1007/bf00128242
https://doi.org/10.1007/bf00128242
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 259:H317-H323
We previously reported in working swine hearts a preferred use of fatty acids during early myocardial reperfusion. The purpose of these studies was to test whether this pattern of substrate oxidation was the result of excess energy demands during mec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd6c709a008d6da055ef163c9fcc1396
https://doi.org/10.1152/ajpheart.1990.259.2.h317
https://doi.org/10.1152/ajpheart.1990.259.2.h317
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 258:H1348-H1356
In intact hearts the beat-to-beat left ventricular systolic pressure-length relationship is not uniquely defined, but rather is history dependent and appears hysteretic. The purpose of these studies was to assess the time course of this phenomenon. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da8629806d92dd26d13ee6f843f66357
https://doi.org/10.1152/ajpheart.1990.258.5.h1348
https://doi.org/10.1152/ajpheart.1990.258.5.h1348