Zobrazeno 1 - 9
of 9
pro vyhledávání: '"S H, Chay"'
Publikováno v:
Xenobiotica. 35:647-660
The metabolism and disposition of LY 368842, a beta 3-adrenergic receptor agonist, were characterized in F344 rats following oral or intravenous administration of [(14)C]LY 368842. These studies were conducted as part of the investigation of the mech
Publikováno v:
Annals of the Academy of Medicine, Singapore. 32
Publikováno v:
Annals of the Royal Australasian College of Dental Surgeons. 15
A spaced dentition can be due to various reasons such as hypodontia, tooth size discrepancy and impeded eruption. The dilemma for clinicians is whether to close, open or redistribute space. Closing space by orthodontics eliminates the need for prosth
Publikováno v:
Australian orthodontic journal. 16(2)
Alveolar bone defects are conditions that impede the progress of orthodontic treatment. This study compared the mechanics of the healing of autogenous intramembranous (IM) bone grafts and grafts comprising a mixture of IM and demineralised bone matri
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 28(4)
The metabolism and disposition of moxonidine (4-chloro-5-(imidazolidin-2-ylidenimino)-6-methoxy-2-methylp yrimidine ), a potent central-acting antihypertensive agent, were investigated in F344 rats. After an i.v. or oral administration of 0.3 mg/kg o
Autor:
S H, Chay, J L, Herman
Publikováno v:
Arzneimittel-Forschung. 48(5)
These studies comprehensively evaluate the distribution of [14C]olanzapine (2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno(2,3-b)-1,5)benzodiazepin e, CAS 132539-06-1, LY170053) a novel anti-schizophrenic compound, following single oral dose administ
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 23(9)
LY255582 is a phenylpiperidine opioid antagonist under development as an appetite suppressant and for the treatment of obesity. Female beagles were administered [14C]LY255582 at dosages of 0.72 mg/kg intravenously or 7.2 mg/kg orally. The majority (5
Autor:
S H, Chay, R C, Pohland
Publikováno v:
Journal of pharmaceutical sciences. 83(9)
Quantitative whole-body autoradiography (QWBA) was evaluated and compared to tissue dissection/liquid scintillation counting (TD/LSC) techniques by determining the tissue distribution of radiocarbon in rats following iv administration of the antibiot
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 21(1)
The biotransformation of the antiinfluenza agent 1,3,4-thiadiazol-2-ylcyanamide (LY217896, I) was studied. In addition to a urea metabolite (II) formed by transformation of the cyanamide functionality, another highly polar metabolite was found in mou