Zobrazeno 1 - 10
of 979
pro vyhledávání: '"S Gorman"'
Autor:
Mariagrazia Di Giuseppe, Katie Aafjes-van Doorn, Vera Békés, Bernard S. Gorman, Karl Stukenberg, Sherwood Waldron
Publikováno v:
Research in Psychotherapy, Vol 27, Iss 1 (2024)
Research into defensive functioning in psychotherapy has thus far focused on patients’ defense use. However, also the defensive functioning of therapists might be significant because of its potential in promoting changes in the patient’s overall
Externí odkaz:
https://doaj.org/article/f554ede3264a42a094d5d33c69d75aff
Autor:
Elizaveta A. Olkhova, Carla Bradshaw, Alasdair Blain, Debora Alvim, Doug M. Turnbull, Fiona E. N. LeBeau, Yi Shiau Ng, Gráinne S. Gorman, Nichola Z. Lax
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-17 (2023)
Abstract Mitochondrial diseases comprise a common group of neurometabolic disorders resulting from OXPHOS defects, that may manifest with neurological impairments, for which there are currently no disease-modifying therapies. Previous studies suggest
Externí odkaz:
https://doaj.org/article/d905e99197394a9cbdda0d8fb7b9226c
Autor:
Direnis Erdinc, Alejandro Rodríguez‐Luis, Mahmoud R Fassad, Sarah Mackenzie, Christopher M Watson, Sebastian Valenzuela, Xie Xie, Katja E Menger, Kate Sergeant, Kate Craig, Sila Hopton, Gavin Falkous, Genomics England Research Consortium, Joanna Poulton, Hector Garcia‐Moreno, Paola Giunti, Carlos A de Moura Aschoff, Jonas A Morales Saute, Amelia J Kirby, Camilo Toro, Lynne Wolfe, Danica Novacic, Lior Greenbaum, Aviva Eliyahu, Ortal Barel, Yair Anikster, Robert McFarland, Gráinne S Gorman, Andrew M Schaefer, Claes M Gustafsson, Robert W Taylor, Maria Falkenberg, Thomas J Nicholls
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 5, Pp 1-21 (2023)
Abstract Topoisomerase 3α (TOP3A) is an enzyme that removes torsional strain and interlinks between DNA molecules. TOP3A localises to both the nucleus and mitochondria, with the two isoforms playing specialised roles in DNA recombination and replica
Externí odkaz:
https://doaj.org/article/c9e7e4ced0784d4394725c67d2a116f4
Autor:
Louise S. Gorman, Helen Ruane, Victoria G. Woof, Jake Southworth, Fiona Ulph, D. Gareth Evans, David P. French
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-9 (2022)
Abstract Background Risk stratified breast cancer screening is being considered as a means of improving the balance of benefits and harms of mammography. Stratified screening requires the communication of risk estimates. We aimed to co-develop person
Externí odkaz:
https://doaj.org/article/cab4a555a0d94f0b982739326f2e6e66
Autor:
The AIMM Trial Group:, Alaa Abouhajar, Lisa Alcock, Theophile Bigirumurame, Penny Bradley, Laura Brown, Ian Campbell, Sylvia Del Din, Julie Faitg, Gavin Falkous, Gráinne S. Gorman, Rachel Lakey, Robert McFarland, Jane Newman, Lynn Rochester, Vicky Ryan, Hesther Smith, Alison Steel, Renae J. Stefanetti, Huizhong Su, Robert W. Taylor, Naomi J.P. Thomas, Helen Tuppen, Amy E. Vincent, Charlotte Warren, Gillian Watson
Publikováno v:
Trials, Vol 23, Iss 1, Pp 1-15 (2022)
Abstract Background Mitochondrial disease is a heterogenous group of rare, complex neurometabolic disorders. Despite their individual rarity, collectively mitochondrial diseases represent the most common cause of inherited metabolic disorders in the
Externí odkaz:
https://doaj.org/article/0e77b4f741a34930bece1b228e941d9a
Autor:
Venumadhav Janganati, Paloma Salazar, Brian J. Parks, Gregory S. Gorman, Paul L. Prather, Eric C. Peterson, Alexander W. Alund, Jeffery H. Moran, Peter A. Crooks, Lisa K. Brents
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction: An active metabolite of buprenorphine (BUP), called norbuprenorphine (NorBUP), is implicated in neonatal opioid withdrawal syndrome when BUP is taken during pregnancy. Therefore, reducing or eliminating metabolism of BUP to NorBUP is a
Externí odkaz:
https://doaj.org/article/851ee0a95e754823870b37ba2b585594
Autor:
David Houghton, Yi Shiau Ng, Matthew A. Jackson, Renae Stefanetti, Paula Hynd, Micheál Mac Aogáin, Christopher J. Stewart, Christopher A. Lamb, Alexandra Bright, Catherine Feeney, Jane Newman, Doug M. Turnbull, Robert McFarland, Alasdair P. Blain, Gráinne S. Gorman
Publikováno v:
Gastro Hep Advances, Vol 1, Iss 4, Pp 666-677 (2022)
Background and Aims: Gastrointestinal (GI) dysmotility is a common and debilitating clinical manifestation in patients with mitochondrial DNA (mtDNA)–related disease with no curative and few effective symptomatic therapies. A low-residue diet (LRD)
Externí odkaz:
https://doaj.org/article/2ccd4656b73646229b46bc482079664a
Autor:
Louise S. Gorman, Donna L. Littlewood, Leah Quinlivan, Elizabeth Monaghan, Jonathan Smith, Stephen Barlow, Roger T. Webb, Navneet Kapur
Publikováno v:
BJPsych Open, Vol 9 (2023)
Background Family involvement has been identified as a key aspect of clinical practice that may help to prevent suicide. Aims To investigate how families can be effectively involved in supporting a patient accessing crisis mental health services. M
Externí odkaz:
https://doaj.org/article/e2172b87e8f642d3909573ed3aa8f74a
Autor:
Julia Tobacyk, Brian J. Parks, Lori Coward, Michael D. Berquist, Gregory S. Gorman, Lisa K. Brents
Publikováno v:
Journal of Clinical and Translational Science, Vol 7, Pp 139-140 (2023)
OBJECTIVES/GOALS: Buprenorphine (BUP) is used for opioid use disorder during pregnancy but causes neonatal opioid withdrawal syndrome (NOWS). The goal of this study was to determine the contribution of the active metabolite, norbuprenorphine (NorBUP)
Externí odkaz:
https://doaj.org/article/5d3dca4f3b85413fb384145a37f29147
Autor:
Hugh S. Gorman
In The Story of N, Hugh S. Gorman analyzes the notion of sustainability from a fresh perspective—the integration of human activities with the biogeochemical cycling of nitrogen—and provides a supportive alternative to studying sustainability thro
