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pro vyhledávání: '"S Gaul"'
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Autor:
Daniel S, Gaul, Natacha, Calatayud, Jürgen, Pahla, Nicole R, Bonetti, Yu-Jen, Wang, Julien, Weber, Samuele, Ambrosini, Luca, Liberale, Sarah, Costantino, Shafeeq A, Mohammed, Simon, Kraler, Lambertus J, Van Tits, Lisa, Pasterk, Daria, Vdovenko, Alexander, Akhmedov, Frank, Ruschitzka, Francesco, Paneni, Thomas F, Lüscher, Giovanni G, Camici, Christian M, Matter
Arterial thrombosis may be initiated by endothelial inflammation or denudation, activation of blood-borne elements or the coagulation system. Tissue factor (TF), a central trigger of the coagulation cascade, is regulated by the pro-inflammatory NF-κ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8c5076c5cac81522ee3928093eff444
https://www.zora.uzh.ch/id/eprint/229340/
https://www.zora.uzh.ch/id/eprint/229340/
Autor:
S Gaul, K Shahzad, R Medert, I Gadi, C Maeder, D Schumacher, A Wirth, S Fatima, J N Boeckel, H Khawaja, M Brune, P P Nawroth, B Isermann, U Laufs, M Freichel
Publikováno v:
European Heart Journal. 43
Background and aims Atherosclerosis, the main pathology underlying cardiovascular diseases is accelerated in diabetic patients (1,2). Genetic mouse models require breeding efforts which are time-consuming and costly. Our aim was to establish a new no
Autor:
Nishtha S. Gaul, Akhilesh Jaiswal, Hongsik Yoon, Taeyoung Lee, Kazutaka Yamane, Joe Versaggi, Rick Carter, Bipul C. Paul
Publikováno v:
2022 IEEE International Memory Workshop (IMW).
Autor:
Sarah Costantino, Przemyslaw Blyszczuk, Johan Auwerx, Melanie Greter, Anne Tailleux, Urs Eriksson, Julien Weber, Christian M. Matter, Simona Stivala, Sokrates Stein, Jürg H. Beer, Melroy X. Miranda, Bart Staels, Thomas F. Lüscher, Kathrin Nussbaum, Tasneem Arsiwala, Burkhard Becher, Francesco Paneni, Raul Mostoslavsky, Michael O. Hottiger, Lavinia Bisceglie, Lambertus J. van Tits, Daniel S. Gaul, Jürgen Pahla
Publikováno v:
Journal of Molecular and Cellular Cardiology. 139:24-32
Aims Sirtuin 6 (Sirt6) is a NAD+-dependent deacetylase that plays a key role in DNA repair, inflammation and lipid regulation. Sirt6-null mice show severe metabolic defects and accelerated aging. Macrophage-foam cell formation via scavenger receptors
Autor:
Daniel S. GAUL, Natacha Calatayud, Jürgen Pahla, Nicole R. Bonetti, Julien Weber, Samuele Ambrosini, Yu-Jen Wang, Luca Liberale, Sarah Costantino, Shafeeq A. Mohammed, Simon Kraler, Lambertus J. Van Tits, Lisa Pasterk, Daria Vdovenko, Alexander Akhmedov, Francesco Paneni, Thomas F. Lüscher, Giovanni G. Camici, Christian M. Matter
Publikováno v:
SSRN Electronic Journal.
Publikováno v:
European Heart Journal. 42
Background and purpose Trimethylamine N-oxide (TMAO) is associated with a higher risk of atherosclerotic diseases. However, the underlying molecular mechanisms are not completely understood. Inflammation and following endothelial-to-mesenchymal trans
Autor:
Benjamin Meder, Holger Thiele, M Andritschke, M. Mueller, S Dimmeler, David John, J.-N Boeckel, Ulrich Laufs, Florian Leuschner, Karoline E. Kokot, Jan Haas, M Moebius-Winkler, S Gaul, B Sheikh, J Kneuer
Publikováno v:
European Heart Journal. 42
Background and purpose Post-transcriptional RNA editing is an important mechanism in the development of human diseases. RNA editing can affect RNA stability and alternative splicing. The aim of our study was to characterize RNA editing and its impact
Autor:
Jasmin M Kneuer, Till Keller, Ulrich Laufs, S Gaul, T Speer, Jes-Niels Boeckel, Alexander Kogel, R Weiss, Benjamin Meder, Holger Thiele, P. Lurz, Jan Haas, T Garfias-Veitel, Tim Meinecke, S. Von Haehling
Publikováno v:
European Heart Journal. 42
Background and purpose Activation of the immune system correlates with the severity and the prognosis of patients with heart failure (HF). This study aims to identify and characterize long non-coding RNAs (lncRNAs) as a potential mechanistic link bet
Autor:
Fabrizio Montecucco, Thomas F. Lüscher, Luca Liberale, Daniel S. Gaul, Giacomo Giacalone, Daria Vdovenko, Sarah Costantino, Julien Weber, Jürgen Pahla, Urs Eriksson, Maria Sessa, Giovanni G. Camici, Vanasa Nageswaran, Vera Fehr, Gerd A. Kullak-Ublick, Alexander Akhmedov, Aurora Semerano, Frank Ruschitzka, Christian M. Matter, Jürg H. Beer, Nicole R. Bonetti, Francesco Paneni
Publikováno v:
European Heart Journal. 41:1575-1587
Aims Aging is an established risk factor for stroke; genes regulating longevity are implicated in the pathogenesis of ischaemic stroke where to date, therapeutic options remain limited. The blood–brain barrier (BBB) is crucially involved in ischaem