Zobrazeno 1 - 10
of 213
pro vyhledávání: '"S Galer"'
Autor:
Dagmar Amtmann, Alyssa M. Bamer, Rana Salem, Arnold R. Gammaitoni, Bradley S. Galer, Mark P. Jensen
Publikováno v:
Journal of Patient-Reported Outcomes, Vol 5, Iss 1, Pp 1-7 (2021)
Abstract Background English versions of the University of Washington Caregiver Stress (UW-CSS) and Benefit (UW-CBS) Scales were developed in the United States (US) to measure impact on caregivers of caring for a child/children. Caregiving stress and
Externí odkaz:
https://doaj.org/article/dd34785cd77c47af824f360219c46ed0
Autor:
N. Öğretmen, R. Schiebel, K. P. Jochum, S. Galer, J. Leitner, S. Khanolkar, M. Yücel, B. Stoll, U. Weis, G. H. Haug
Publikováno v:
Geochemistry, Geophysics, Geosystems, Vol 23, Iss 10, Pp n/a-n/a (2022)
Abstract Closure of the Central American Seaway (CAS) and hydrology of the Caribbean Sea triggered Northern Hemisphere Glaciation and played an important role in the Pliocene to modern‐day climate re‐establishing the deep and surface ocean curren
Externí odkaz:
https://doaj.org/article/320c98b24f8e44659304a9919e0c0858
Publikováno v:
Mitochondrion. 68:1-9
TK2d is an ultrarare autosomal recessive mitochondrial DNA depletion syndrome. Nucleoside therapy improves or stabilizes disease across key outcomes including survival, ambulation, and requirement for mechanical ventilation. However, little is known
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9415ed82ae3b3b54234d723d29fd9bf9
https://doi.org/10.1016/j.mito.2022.10.003
https://doi.org/10.1016/j.mito.2022.10.003
Autor:
Parthena Martin, Thadd Reeder, Jo Sourbron, Peter A. M. de Witte, Arnold R. Gammaitoni, Bradley S. Galer
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 16, p 8416 (2021)
Developmental and epileptic encephalopathies (DEEs) are complex conditions characterized primarily by seizures associated with neurodevelopmental and motor deficits. Recent evidence supports sigma-1 receptor modulation in both neuroprotection and ant
Externí odkaz:
https://doaj.org/article/0a5dbf36063a4f5a83630f3300c908b6
Autor:
Bradley S. Galer, Elizabeth J. Donner, Sanjeev V. Kothare, Elaine C. Wirrell, An-Sofie Schoonjans, Antonio Gil-Nagel, J. Helen Cross, Michael Lock, Berten Ceulemans, Orrin Devinsky, Lieven Lagae, Arnold R. Gammaitoni, Anupam Agarwal
Publikováno v:
Seizure: European journal of epilepsy
PURPOSE: To assess the impact of fenfluramine (FFA) on the expected mortality incidence, including sudden unexpected death in epilepsy (SUDEP), in persons with Dravet syndrome (DS). METHODS: In this pooled analysis, total time of exposure for persons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e75835983609b945b84537f7bf55a21b
https://doi.org/10.1016/j.seizure.2021.10.024
https://doi.org/10.1016/j.seizure.2021.10.024
Autor:
M. Scott Perry, Stéphane Auvin, Bradley S. Galer, Orrin Devinsky, Arnold R. Gammaitoni, Nicola Specchio, Adam Strzelczyk, David Dai, Joseph Sullivan, Antonio Gil-Nagel
Publikováno v:
Epilepsia. 63:130-138
OBJECTIVE The number, unpredictability, and severity of seizures experienced by patients with Dravet syndrome (DS) negatively impact quality of life (QOL) for patients, caregivers, and families. Metrics are needed to assess whether patients with resi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7eab0fe5141f6c2f028364f9144526d
https://doi.org/10.1111/epi.17106
https://doi.org/10.1111/epi.17106
Autor:
Kim I. Bishop, Peter K. Isquith, Gerard A. Gioia, Kelly G. Knupp, Ingrid E. Scheffer, Rima Nabbout, Nicola Specchio, Joseph Sullivan, Stéphane Auvin, J. Helen Cross, Renzo Guerrini, Gail Farfel, Bradley S. Galer, Arnold R. Gammaitoni
Publikováno v:
Epilepsybehavior : EB. 138
To evaluate whether fenfluramine (FFA) is associated with improvement in everyday executive function (EF)-self-regulation-in preschool-aged children with Dravet syndrome (DS).Children with DS received placebo or FFA in one of two phase III studies (f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de2f7ab2fdda5badeec84cbbcd0319a7
https://pubmed.ncbi.nlm.nih.gov/36463826
https://pubmed.ncbi.nlm.nih.gov/36463826
Autor:
Mark P. Jensen, Arnold R. Gammaitoni, Bradley S. Galer, Rana Salem, Dana Wilkie, Dagmar Amtmann
Publikováno v:
Epilepsy research. 185
Prior research has demonstrated durable and profound reductions in seizure frequency and improvements in executive functions in individuals with Dravet syndrome (DS) who are treated with fenfluramine (FFA). This study aimed to understand the benefits
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bb0ee4901ab7bed61c32820ab5bacbc
https://pubmed.ncbi.nlm.nih.gov/35843016
https://pubmed.ncbi.nlm.nih.gov/35843016
Autor:
Kelly G. Knupp, Ingrid E. Scheffer, Berten Ceulemans, Joseph E. Sullivan, Katherine C. Nickels, Lieven Lagae, Renzo Guerrini, Sameer M. Zuberi, Rima Nabbout, Kate Riney, Svetlana Shore, Anupam Agarwal, Michael Lock, Gail M. Farfel, Bradley S. Galer, Arnold R. Gammaitoni, Ronald Davis, Antonio Gil-Nagel
Publikováno v:
JAMA neurology
IMPORTANCE: New treatment options are needed for patients with Lennox-Gastaut syndrome (LGS), a profoundly impairing, treatment-resistant, developmental and epileptic encephalopathy. OBJECTIVE: To evaluate the efficacy and safety of fenfluramine in p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::890f47c2b632f50d1d98dce3cbd7fcb7
https://pubmed.ncbi.nlm.nih.gov/35499850
https://pubmed.ncbi.nlm.nih.gov/35499850
Autor:
Wyman W. Lai, Milka Pringsheim, Anupam Agarwal, Pierre C. Wong, Bradley S. Galer, Gail Farfel, Martin G. Keane
Publikováno v:
Epilepsia
Objective Fenfluramine, which was previously approved as a weight loss drug, was withdrawn in 1997 when reports of cardiac valvulopathy emerged. The present study was conducted in part to characterize the cardiovascular safety profile of low‐dose f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d61a350b28e0e38b99861e5813145b3
https://doi.org/10.1111/epi.16638
https://doi.org/10.1111/epi.16638