Zobrazeno 1 - 10
of 12
pro vyhledávání: '"S G Terekhin"'
Autor:
I. V. Rogachevskii, S. A. Podzorova, Boris V. Krylov, S. G. Terekhin, V. B. Plakhova, V. A. Penniyaynen
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 100:43-52
A gamma-pyrone derivative, comenic acid, activates the opioid-like receptor-mediated signaling pathway that modulates the NaV1.8 channels in the primary sensory neuron membrane. These channels are responsible for the generation of the nociceptive sig
Autor:
V. A. Penniyaynen, S. A. Podzorova, S. G. Terekhin, A. D. Kalinina, I. V. Rogachevsky, Boris V. Krylov, V. B. Plakhova
Publikováno v:
Biophysics. 66:579-588
The possible mechanisms of ligand–receptor binding of arginine-containing tetrapeptides with the NaV1.8 channels in the primary sensory neuron were investigated. Ac-RERR-NH2 tetrapeptide, acting outside the neuronal membrane, was found to decrease
Autor:
S. A. Podzorova, S. G. Terekhin, V. A. Penniyaynen, A. D. Kalinina, V. B. Plakhova, Boris V. Krylov
Publikováno v:
Neuroscience and Behavioral Physiology. 51:831-836
Local voltage clamping and organotypic cultures of nervous tissue were used to study the actions of a series of agents whose activity is associated with the functioning of the GABAergic and NOergic systems on slow sodium channels. GABA was found not
Autor:
I. V. Rogachevskii, S. A. Podzorova, V. A. Penniyaynen, Boris V. Krylov, V. B. Plakhova, S. G. Terekhin
Publikováno v:
Pathophysiology. 26:245-252
Comenic acid (CA), a specific agonist of opioid-like receptors, effectively and safely relieves neuropathic pain by decreasing the NaV1.8 channel voltage sensitivity in the primary sensory neuron membrane. CA triggers downstream signaling cascades, i
Autor:
Polina V. Plotnikova, S. G. Terekhin, A. I. Erofeev, Ilya Bezprozvanny, O. L. Vlasova, O. A. Zakharova
Publikováno v:
Neuroscience and Behavioral Physiology. 49:199-207
We report here a comparative (using chemical, electrical, and optical stimulation) study of the electrophysiological properties of cultured hippocampal neurons from transgenic animals expressing a mutant presenilin 1 protein. All three types of stimu
Autor:
O. L. Vlasova, O. A. Zakharova, S. G. Terekhin, Polina V. Plotnikova, Ilya Bezprozvanny, A. I. Erofeev
Publikováno v:
Журнал высшей нервной деятельности им И П Павлова. :63-74
Publikováno v:
Medical academic journal. 19:44-45
The aim of the study was to elucidate the molecular mechanisms of the interconnection of the GABA-ergic and nociceptive systems at the level of the peripheral division of the CNS. The data obtained indicate that GABA does not affect the activation ga
Autor:
S. G. Terekhin, Polina V. Plotnikova, A. I. Erofeev, O. A. Zakharova, M. V. Matveev, O. L. Vlasova
Publikováno v:
St. Petersburg Polytechnical University Journal: Physics and Mathematics. 1:256-263
The article is devoted to problems of realization and application of optogenetic methods used to identify reasons of various diseases, to monitor the biochemical processes of cell activity and to study various organisms. The problems of delivery, emb
Autor:
O. L. Vlasova, A. I. Erofeev, S. G. Terekhin, V. A. Kilimnik, Ilya Bezprozvanny, M. V. Matveev, O. A. Zakharova
Publikováno v:
Journal of Physics: Conference Series. 917:042023
Autor:
S. G. Terekhin, O. L. Vlasova, A. I. Erofeev, Ilya Bezprozvanny, M. V. Matveev, O. A. Zakharova
Publikováno v:
Journal of Physics: Conference Series. 741:012067
Optogenetic is a powerful method that allows to modulate cellular physiological properties. In our article, we demonstrate changes of electrical properties of cellular membranes on HEK-293T and hippocampal neurons transfected with channelrhodopsins a