Zobrazeno 1 - 10
of 11
pro vyhledávání: '"S G Irving"'
Publikováno v:
Hematopathology and molecular hematology. 11(1)
Nonrandom use of immunoglobulin variable (V) gene segments is a feature of some B-cell neoplasms, possibly as a consequence of antigen selection. In Hodgkin's disease, the primary tissues, cell lines, and even single Reed-Sternberg cells can carry im
Publikováno v:
Lymphokine and cytokine research. 11(3)
AT464 and AT744 are two cytokines encoded by mitogen-induced genes from human T lymphocytes. These proteins belong to a family of structurally related chemotactic proteins associated with inflammation. By expression of their full length cDNAs in COS
Autor:
S G Irving, Ulrich Siebenlist, Hiroaki Mitsuya, Kurt C. Gunter, John J. Wright, Kathleen Kelly
Publikováno v:
Science (New York, N.Y.). 248(4955)
Gene products encoded by the human T cell leukemia virus (HTLV) types I and II mediate transformation by the transactivation of cellular genes necessary for proliferation, probably including transcriptional regulatory factors. By searching for factor
Two inflammatory mediator cytokine genes are closely linked and variably amplified on chromosome 17q
Autor:
Balke J, S G Irving, Ulrich Siebenlist, Cynthia C. Morton, Parris R. Burd, O W McBride, Kathleen Kelly, Peter F. Zipfel
Publikováno v:
Nucleic Acids Research. 18:3261-3261
Mitogenic stimulation of resting T cells results in the de novo transcription of a large number of genes including those encoding regulatory molecules such as lymphokines. The genomic organization of two newly described induced lymphokine genes, 464.
Publikováno v:
The Journal of Immunology. 142:1582-1590
Previously we have isolated about 60 novel cDNA clones whose corresponding mRNAs are induced by mitogenic activation in human peripheral blood T cells. Here we describe the primary structure and regulation of two such cloned genes, pAT 464 and pAT 74
Publikováno v:
Molecular and Cellular Biology. 9:1034-1040
The delivery of a mitogenic signal to T cells via any one of several cell surface molecules elicits a variety of intracellular responses, some or all of which regulate subsequent gene expression events. The expression of nine novel mitogen-induced ge
Publikováno v:
Molecular and Cellular Biology. 9:1041-1048
We describe the isolation and characterization of more than 60 novel cDNA clones that constitute part of the immediate genetic response to resting human peripheral blood T cells after mitogen activation. This primary response was highly complex, both
Publikováno v:
The Journal of Immunology. 142:3286-3291
We have examined the effect of cyclosporin A (CSA) on the mitogen-induced expression of 11 genes previously cloned from mitogen-activated T lymphocytes. Levels of induced gene expression in the human T cell line Jurkat were determined by mRNA blottin
Publikováno v:
American journal of veterinary research. 46(10)
A recently isolated Israeli retrovirus from a sheep with maedi-visna was compared with other retroviruses, using cDNA-RNA hybridization in solution. The Israeli isolate was shown to have close, if not identical, genetic homologic features with the ov
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 142(5)
Previously we have isolated about 60 novel cDNA clones whose corresponding mRNAs are induced by mitogenic activation in human peripheral blood T cells. Here we describe the primary structure and regulation of two such cloned genes, pAT 464 and pAT 74