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Monoclonal antibody 197 (anti‐FcγRI) infusion in a patient with immune thrombocytopenia purpura (ITP) results in down‐modulation of FcγRI on circulating monocytes

Autor: K. D. Coleman, S. G. Ericson, P. Ely, Michael W. Fanger, Paul M. Guyre, S. Baker, K. Wardwell

Publikováno v: British Journal of Haematology. 92:718-724

A 44-year old woman with refractory immune thrombocytopenia purpura was treated with the murine monoclonal antibody 197 in a phase 1 trial. It vitro studies have demonstrated that the monoclonal antibody 197 (subclass IgG2a) binds to two distinct epi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c075d0f43c26f5bb253dc997499b45f
https://doi.org/10.1046/j.1365-2141.1996.393931.x

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The clinical impact of antibacterial prophylaxis and cycling antibiotics for febrile neutropenia in a hematological malignancy and transplantation unit

Autor: G R Hobbs, Marcel P. Devetten, M Craig, S G Ericson, A R Sarwari, Aaron Cumpston

Publikováno v: Bone marrow transplantation. 39(8)

Febrile neutropenia is an expected complication during treatment of aggressive hematological malignancies and hematopoietic cell transplantation. We conducted a prospective cohort trial to determine the effects and safety of prophylactic fluoroquinol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d871047ee677625f26143cf36efb879a
https://pubmed.ncbi.nlm.nih.gov/17322937

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Fluorescence-imaging assay for cytotoxic plaque formation and for growth toward confluency of adherent cells

Autor: G, Gericke, N, Benoit, K A, Orndorff, A L, Givan, S G, Ericson

Publikováno v: Cytometry. 33(1)

A nondestructive fluorescence-imaging assay is described for quantitating the number and size of plaques formed over time by cytotoxic effector cells in a monolayer of target cells. It can also be used to assay the growth of adherent cells toward con

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::37de05b17109e6999ccb604976f09151
https://pubmed.ncbi.nlm.nih.gov/9725557

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Interleukin-6 production by human neutrophils after Fc-receptor cross-linking or exposure to granulocyte colony-stimulating factor

Autor: S G, Ericson, Y, Zhao, H, Gao, K L, Miller, L F, Gibson, J P, Lynch, K S, Landreth

Publikováno v: Blood. 91(6)

Polymorphonuclear neutrophils (PMNs) are essential effector cells in host defense and tissue inflammatory responses. These responses may be initiated after cross-linking of cell surface Fc receptors that bind the constant portion of IgG (FcgammaR). W

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::aac8ad6994bab1d0193248aa17444b76
https://pubmed.ncbi.nlm.nih.gov/9490696

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The role of polymorphonuclear neutrophils (PMNs) in clearance of granulocyte colony-stimulating factor (G-CSF) in vivo and in vitro

Autor: S G, Ericson, H, Gao, G H, Gericke, L D, Lewis

Publikováno v: Experimental hematology. 25(13)

Previous studies have suggested that in vivo granulocyte colony-stimulating factor (G-CSF) pharmacokinetics may change over time. We studied three patients treated with high-dose chemotherapy followed by autologous bone marrow transplantation (ABMT)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f2c40b9db804f33fed5272c459509297
https://pubmed.ncbi.nlm.nih.gov/9406990

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Disruption of bone marrow stromal cell function by etoposide

Autor: L F, Gibson, J, Fortney, K S, Landreth, D, Piktel, S G, Ericson, J P, Lynch

Publikováno v: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 3(3)

Long-term deficits in hematopoietic reconstitution following aggressive chemotherapeutic regimens used before transplantation may be a result, in part, of damage to the bone marrow microenvironment. Disruption of the hematopoietic microenvironment is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::844bec1df916cb05bb0cfd003f97ce51
https://pubmed.ncbi.nlm.nih.gov/9310189

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Anti-body-dependent cellular cytotoxicity (ADCC) function of peripheral blood polymorphonuclear neutrophils (PMN) after autologous bone marrow transplantation (ABMT)

Autor: S G, Ericson, C A, Guyre, N E, Benoit, K R, Meehan, L E, Mills, M W, Fanger

Publikováno v: Bone marrow transplantation. 16(6)

Rapid recovery of the number and function of polymorphonuclear neutrophils (PMN) is critical to recovery from bone marrow transplantation. Although it is relatively easy to measure PMN number recovery, the evaluation of the functional recovery of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c8130ae3becbad5f9740b76fef33e3c2
https://pubmed.ncbi.nlm.nih.gov/8750271

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The effect of recombinant human interleukin-3 and recombinant human granulocyte-macrophage colony-stimulating factor on Fc gamma receptor expression and antibody-dependent cellular cytotoxicity of hematopoietic progenitor cells during in vitro myeloid maturation

Autor: S G, Ericson, N E, Benoit, L E, Mills, M W, Fanger

Publikováno v: Experimental hematology. 22(3)

Enriched progenitor cell fractions from human bone marrow were induced to undergo myeloid maturation in culture using recombinant human interleukin-3 (rhIL-3) and granulocyte-macrophage colony stimulating factor (rhGM-CSF). A negative selection metho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::668ff198a9af06ba510b50fea4849e14
https://pubmed.ncbi.nlm.nih.gov/7509291

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