Zobrazeno 1 - 10
of 290
pro vyhledávání: '"S Görög"'
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 29:1153-1157
The impurity profile of ethynodiol diacetate was investigated using the HPLC/UV/MS method. Using the slightly modified HPLC method of USP 24 two impurities, earlier isolated by preparative HPLC and investigated by NMR spectroscopy were separated and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50636081a61c8de18cd2597a2ec315d9
https://doi.org/10.1016/s0731-7085(02)00165-6
https://doi.org/10.1016/s0731-7085(02)00165-6
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 17:1029-1036
Reversed-phase HPLC methods using C-18 and C-8 columns as well as various isocratic and gradient systems with aqueous ammonium acetate, methanol and acetonitrile are described for the separation of the impurities of mazipredone (11beta,17-dihydroxy-2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0f56c6821d94e022c9bda7a49330881
https://doi.org/10.1016/s0731-7085(98)00068-5
https://doi.org/10.1016/s0731-7085(98)00068-5
Publikováno v:
Analytica Chimica Acta. 352:231-237
Reversed phase HPLC methods have been developed for the separation of related peptides from two synthetic thymopoietin fragments: thymotrinan (Arg-Lys-Asp) and thymocartin (Arg-Lys-Asp-Val), as experimental immunostimulant drugs. The optimization of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f416030ef4141b81e5c88a2ba6319e42
https://doi.org/10.1016/s0003-2670(97)00119-0
https://doi.org/10.1016/s0003-2670(97)00119-0
Autor:
S. Görög, Katalin Varga, J. Brlik, G. Balogh, F. Dravecz, A. Laukó, A. Csehi, M. Gasdag, Peter Horvath, M. Babják
Publikováno v:
Talanta. 44:1517-1526
A general scheme is set up for the estimation of the impurity profile of bulk drug substances by the complex use of chromatographic, spectroscopic and hyphenated techniques. Several examples are presented as illustrations to the scheme from the autho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80563eb5490d3eab3b0f1e95b7ab7e7d
https://doi.org/10.1016/s0039-9140(96)02179-0
https://doi.org/10.1016/s0039-9140(96)02179-0
Autor:
Katalin Varga, Peter Horvath, S. Görög, A. Csehi, F. Dravecz, M. Rényei, G. Balogh, Anna Laukó, J. Brlik, Zs. Halmos
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 15:1343-1349
A new apolar impurity (3,17 alpha-diethinyl-13-ethyl-3,5-gonadiene-17-ol, IIb) was detected and identified in norgestrel with the aid of thin-layer and high-performance chromatography and spectroscopic techniques. IIb is the product of the acid-catal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d800195c2ba1168a696d77e5a347ddf0
https://doi.org/10.1016/s0731-7085(96)02008-0
https://doi.org/10.1016/s0731-7085(96)02008-0
Autor:
J. Brlik, Peter Horvath, Zs. Halmos, M. Kislaki, Gy. Domany, A. Nemes, Cs. Szantay, Katalin Varga, S. Görög, A. Csehi
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 15:1-5
Besides several known impurities in cimetidine, two additional compounds at levels below 0.1% were detected by ion-pair reversed-phase high-performance liquid chromatography (HPLC). The impurities were isolated from crude cimetidine using normal-phas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5284772ad789f5f5aeb5f59478581788
https://doi.org/10.1016/0731-7085(96)01815-8
https://doi.org/10.1016/0731-7085(96)01815-8
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 14:1115-1124
4-Ene-3-ketosteroids and 17-ketosteroids were quantitatively transformed into the corresponding hydrazones using Girard P and T reagents, respectively. The positively charged derivatives were separated by capillary electrophoresis. The spectrophotome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc01479f96913ade9196b6ea2725d27c
https://doi.org/10.1016/0731-7085(95)01693-7
https://doi.org/10.1016/0731-7085(95)01693-7
Publikováno v:
Journal of High Resolution Chromatography. 18:259-262
Flumecinol and related compounds can, without derivatization, be separated into their enantiomers by gas chromatography on cyclodextrin phases; permethylated β-cyclodextrin dissolved in OV-1701 can be particularly recommended. Thermodynamic data des
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c22839f63ea0cb65a31d6bd3911556ba
https://doi.org/10.1002/jhrc.1240180410
https://doi.org/10.1002/jhrc.1240180410