Zobrazeno 1 - 10
of 21
pro vyhledávání: '"S G, Volsen"'
Autor:
S. G. Volsen, M. M. Masson
Publikováno v:
The Quality Assurance Journal. 12:57-63
The need for Quality standards in non-regulated research is a matter of considerable current debate. Whilst a number of such guidelines have been developed over recent years, their successful implementation remains a challenge to all. In order to ass
Identification and cellular localisation of voltage-operated calcium channels in immature rat testis
Autor:
Angela D'Agostino, Emanuele Sher, Kerry L. Price, Matthew Kemp, Ruth E. Beattie, Alessandra Fragale, S. G. Volsen, Matthew B. Reeves, Salvatore Aguanno, Peter J. Craig
Publikováno v:
Molecular and Cellular Endocrinology. 162:25-33
Sertoli cells regulate the spermatogenic process mainly through the secretion of a complex fluid into the lumen of the seminiferous tubules behind the blood–testis barrier, containing many of the essential proteins necessary for maintenance and mat
Autor:
Yury D. Bogdanov, Annette C. Dolphin, Karen M. Page, C Canti, S. G. Volsen, M. Li, N. L. Brice
Publikováno v:
European Journal of Neuroscience. 12:894-902
Voltage-dependent calcium channels consist of a pore-forming transmembrane alpha 1-subunit, which is known to associate with a number of accessory subunits, including alpha 2-delta- and beta-subunits. The beta-subunits, of which four have been identi
Autor:
M D Banerjee, Elizabeth A. Folly, Peter J. Craig, S L Carney, Edward Perez-Reyes, S. G. Volsen, Ruth E. Beattie, Emanuele Sher, Matthew B. Reeves, John V. Priestley
Publikováno v:
European Journal of Neuroscience. 11:2949-2964
The molecular identity of a gene which encodes the pore-forming subunit (alpha1G) of a member of the family of low-voltage-activated, T-type, voltage-dependent calcium channels has been described recently. Although northern mRNA analyses have shown a
Autor:
Edward Perez-Reyes, Annette C. Dolphin, Ruth E. Beattie, Jung-Ha Lee, Peter J. Craig, L. L. Cribbs, J. Richards, S. G. Volsen, Christopher N. Wyatt
Publikováno v:
The Journal of Physiology. 519:35-45
1 The effect has been examined of the accessory α2-δ and β subunits on the properties of α1G currents expressed in monkey COS-7 cells and Xenopus oocytes. 2 In immunocytochemical experiments, the co-expression of α2-δ increased plasma membrane
Autor:
S. G. Volsen, Niki C. Day, W. Smith, Peter J. Craig, Pamela J. Shaw, Michael M. Harpold, Steve B. Ellis, Paul G. Ince, Ruth E. Beattie, Alison L. McCormack
Publikováno v:
Molecular Brain Research. 60:259-269
The beta subunits of voltage-dependent calcium channels (VDCC) modulate the electrophysiology and cell surface expression of pore-forming alpha1 subunits. In the present study we have investigated the distribution of beta1,beta2,beta3 and beta4 in th
Publikováno v:
Letters in Drug Design & Discovery. 3:286-288
Autor:
Régis C. Lambert, Michel De Waard, Yves Maulet, Jérôme Mouton, S. G. Volsen, Anne Feltz, Ruth E. Beattie
Publikováno v:
The Journal of Neuroscience. 17:6621-6628
At the molecular level, our knowledge of the low voltage-activated Ca2+channel (T-type) has made little progress. Using an antisense strategy, we investigated the possibility that the T-type channels have a structure similar to high voltage-activated
Publikováno v:
Neuropharmacology. 36:405-409
Treatment of cerebellar neurones in culture with an antisense oligonucleotide (ODN) against α1A, reduced the whole-cell P-type calcium channel current relative to mismatch ODN treated controls (p < 0.001). Therefore, AgaIVA (50 nM) reduced whole-cel
Autor:
S. G. Volsen, Tim Williams, Peter J. Craig, Ruth E. Beattie, David Lodge, Michael M. Harpold, Steven B. Ellis, Alison L. McCormack, Paul G. Ince, Pamela J. Shaw, W. Smith, Nicola C. Day
Publikováno v:
Neuroscience. 71:1013-1024
The distribution of voltage-dependent calcium channel subunits in the central nervous system may provide information about the function of these channels. The present study examined the distribution of three alpha-1 subunits, alpha 1A, alpha 1B and a