Zobrazeno 1 - 10 of 121 pro vyhledávání: '"S G, Polonik"'
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The Chaperone Inducer U133 Eliminates Anhedonia and Prevents Neurodegeneration in Monoaminergic Emotiogenic Brain Structures in a Preclinical Model of Parkinson’s Disease in Aged Rats
Autor: Yu. F. Pastukhov, S. G. Polonik, D. V. Belan, I. V. Ekimova, M. B. Pazi
Publikováno v: Journal of Evolutionary Biochemistry and Physiology. 57:1130-1141
Parkinson’s disease (PD) is a neurodegenerative disorder mainly diagnosed in elderly patients, which is now considered incurable. To date, there are no effective neuroprotectors suitable to treat PD patients. We have previously demonstrated that U1
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fff162c506bd1896e01bcbe1699c3803
https://doi.org/10.1134/s0022093021050148
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4
Assessment of the Efficacy of Preventive Therapy with Chaperone Inducer U133 in a Model of the Preclinical Stage of Parkinson’s Disease in Elderly Rats
Autor: S. G. Polonik, D. V. Belan, I. V. Ekimova
Publikováno v: Neuroscience and Behavioral Physiology. 51:673-680
Parkinson’s disease (PD) is a chronic relentlessly progressive neurodegenerative disease mainly affecting dopamine (DA)-ergic neurons in the nigrostriatal system of the brain. PD mostly affects elderly people and is incurable. Impairments to the co
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b46dce28250af77ed99a046084ba029b
https://doi.org/10.1007/s11055-021-01120-3
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5
U-133, a Chaperone Inducer, Eliminates Sleep Disturbances in a Model of the Preclinical Stage of Parkinson’s Disease in Aged Rats
Autor: T. S. Shemyakova, I. V. Ekimova, V. V. Simonova, S. G. Polonik, Yu. F. Pastukhov, M. A. Guzeev
Publikováno v: Advances in Gerontology. 10:254-259
Parkinson’s disease (PD) is a chronic, progressive neurodegenerative disease that is closely associated with aging. It is considered incurable due to its late diagnosis and the use of symptomatic treatment, which cannot alter the molecular mechanis
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::faaaf93eaeae4f49ba93b2dc4e9aa719
https://doi.org/10.1134/s2079057020030133
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6
Synthesis and properties of water-soluble 5,8-dihydroxy-1,4-naphthoquinone thioglucosides structurally related to echinochrome
Autor: S. G. Polonik
Publikováno v: Russian Journal of Organic Chemistry. 45:1474-1480
Acetylated hydroxynaphthazarin di- and trithioglucosides structurally related to echinochrome were synthesized. Their deacetylation by the action of sodium methoxide in methanol and the effect of hydroxy groups on this process were studied. Water-sol
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::354facfb2dc125d175525ff2600e42d5
https://doi.org/10.1134/s1070428009100091
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