Zobrazeno 1 - 10
of 1 715
pro vyhledávání: '"S Forbes"'
Autor:
Shradha Khanduja, Shoshana M.K. Bloom, Vishnu Raman, Chinmay P. Deshpande, Christopher L. Hall, Neil S. Forbes
Publikováno v:
iScience, Vol 27, Iss 6, Pp 109813- (2024)
Summary: As therapies, oncolytic viruses regress tumors and have the potential to induce antitumor immune responses that clear hard-to-treat and late-stage cancers. Despite this promise, clearance from the blood prevents treatment of internal solid t
Externí odkaz:
https://doaj.org/article/4c4b7e9c228d47c5a27670d89ada1513
Publikováno v:
Microbial Biotechnology, Vol 17, Iss 5, Pp n/a-n/a (2024)
Abstract Immunotherapies have revolutionized cancer treatment. These treatments rely on immune cell activation in tumours, which limits the number of patients that respond. Inflammatory molecules, like lipopolysaccharides (LPS), can activate innate i
Externí odkaz:
https://doaj.org/article/fdb0802046aa450693ff071ba5a55d95
Autor:
Vishnu Raman, Lars M. Howell, Shoshana M. K. Bloom, Christopher L. Hall, Victoria E. Wetherby, Lisa M. Minter, Ashish A. Kulkarni, Neil S. Forbes
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionImmunotherapies have shown great promise, but are not effective for all tumors types and are effective in less than 3% of patients with pancreatic ductal adenocarcinomas (PDAC). To make an immune treatment that is effective for more cance
Externí odkaz:
https://doaj.org/article/944ab464cdd44703a74bbcb1fec0ab5b
Autor:
J. Elbez-Uzan, L. Williams, S. Forbes, A. Dodaro, R. Stieglitz, M.I. Airila, J. Holden, S. Rosanvallon
Publikováno v:
Nuclear Fusion, Vol 64, Iss 3, p 037001 (2024)
The discussion in the international community on how fusion power plants (FPPs) will be licenced and regulated is ongoing. As such, there is a concerted drive from the European stakeholders to understand the requirements from such a framework and how
Externí odkaz:
https://doaj.org/article/eabd547fc0514320973001bf1f5e4315
Autor:
Vishnu Raman, Nele Van Dessel, Christopher L. Hall, Victoria E. Wetherby, Samantha A. Whitney, Emily L. Kolewe, Shoshana M. K. Bloom, Abhinav Sharma, Jeanne A. Hardy, Mathieu Bollen, Aleyde Van Eynde, Neil S. Forbes
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
The limited ability of cancer therapeutics in crossing the cancer cell membrane hampers their therapeutic potential. Here, the authors report Salmonella-based system for intracellular delivery of protein drugs, e.g. caspase-3, and show reduction of t
Externí odkaz:
https://doaj.org/article/e8eca79a91024002a55851a8991f0340
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-16 (2019)
Abstract Background Salmonella have potential as anticancer therapeutic because of their innate tumor specificity. In clinical studies, this specificity has been hampered by heterogeneous responses. Understanding the mechanisms that control tumor col
Externí odkaz:
https://doaj.org/article/677fda5e1d9f4b6595ca54acfefb414e
Publikováno v:
Journal of Hospital Infection. 134:138-146
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4fd3d617d560eeb6eb35ef11057d8901
https://doi.org/10.1016/j.jhin.2023.02.004
https://doi.org/10.1016/j.jhin.2023.02.004
Autor:
Tanu Rana, Olga Y Korolkova, Girish Rachakonda, Amanda D Williams, Alexander T Hawkins, Samuel D James, Amos M Sakwe, Nian Hui, Li Wang, Chang Yu, Jeffrey S Goodwin, Michael G Izban, Regina S Offodile, Mary K Washington, Billy R Ballard, Duane T Smoot, Xuan-Zheng Shi, Digna S Forbes, Anil Shanker, Amosy E M'Koma
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0246393 (2021)
Evidence link bacterial enterotoxins to apparent crypt-cell like cells (CCLCs), and Alpha Defensin 5 (DEFA5) expansion in the colonic mucosa of Crohn's colitis disease (CC) patients. These areas of ectopic ileal metaplasia, positive for Paneth cell (
Externí odkaz:
https://doaj.org/article/030b11b00a114d88968c225591f8ba7c
Autor:
Ana Miller-ter Kuile, Austen Apigo, An Bui, Kirsten Butner, Jasmine N. Childress, Stephanie Copeland, Bartholomew P. DiFiore, Elizabeth S. Forbes, Maggie Klope, Carina I. Motta, Devyn Orr, Katherine A. Plummer, Daniel L. Preston, Hillary S. Young
Publikováno v:
Biology letters. 18(10)
Predator–prey interactions shape ecosystem stability and are influenced by changes in ecosystem productivity. However, because multiple biotic and abiotic drivers shape the trophic responses of predators to productivity, we often observe patterns,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d260bdd85f05a17dc6d3c8844af55f6a
https://pubmed.ncbi.nlm.nih.gov/36287142
https://pubmed.ncbi.nlm.nih.gov/36287142
Publikováno v:
Biotechnology and Bioengineering. 120:1437-1448
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b76a87f3b23faca38ec76e2b7c3b4366
https://doi.org/10.1002/bit.28340
https://doi.org/10.1002/bit.28340