Zobrazeno 1 - 10
of 12
pro vyhledávání: '"S F, O'Brien"'
Publikováno v:
Transfusion medicine (Oxford, England). 23(5)
Blood donors in Canada have been tested for Human T-Cell Lymphotropic Virus (HTLV) since 1990. We report the epidemiology, risk factors and lookback/traceback of HTLV-positive donors/recipients.The annual HTLV rate was calculated from 1990 to 2010. R
Publikováno v:
Vox sanguinis. 104(3)
In China, paid donation is prohibited by law. There is little literature assessing donor motivation in China, and comparison with western countries such as Canada is important in understanding the application of Western literature. We compared motiva
Publikováno v:
Vox sanguinis. 103(1)
Estimates of the viral residual risk should be updated to reflect current incidence of infection in blood donors. Incidence rates were estimated for allogeneic whole-blood donations made to Canadian Blood Services from 2006 to 2009 based on transmiss
Publikováno v:
British journal of pharmacology. 133(4)
The effects of oxidative stress on vascular function in the insulin-resistant state were assessed in mesenteric resistance arteries of obese, insulin-resistant (cp/cp) and lean, normal (+/?) JCR : LA-cp rats. Nitric oxide-mediated relaxation of norad
Beneficial insulin-sensitizing and vascular effects of S15261 in the insulin-resistant JCR:LA-cp rat
Autor:
J C, Russell, D, Ravel, J P, Pégorier, P, Delrat, R, Jochemsen, S F, O'Brien, S E, Kelly, S T, Davidge, D N, Brindley
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 295(2)
S15261, a compound developed for the oral treatment of type II diabetes, is cleaved by esterases to the fragments Y415 and S15511. The aim was to define the insulin-sensitizing effects of S15261, the cleavage products, and troglitazone and metformin
Publikováno v:
Clinical and investigative medicine. Medecine clinique et experimentale. 23(2)
To test the efficacy of chelation therapy, an alternative medical treatment, as an antiatherosclerotic procedure, using an animal model of insulin resistance and vascular disease.A prospective animal experiment with procedures modelled on human chela
Publikováno v:
Canadian journal of physiology and pharmacology. 77(1)
Obesity and insulin resistance are strongly associated with an increased risk of vascular disease. Vasomotion is the cyclic variation in the diameter of arteries and is a general feature of the vasculature that may have important physiological conseq
Publikováno v:
Canadian journal of physiology and pharmacology. 76(1)
Insulin resistance is associated with an increased risk of cardiovascular disease that is probably related to abnormalities of vascular wall function. The JCR:LA-cp rat is a unique animal model of human vascular disease that exhibits a profound insul
Publikováno v:
Diabetic medicine : a journal of the British Diabetic Association. 14(11)
We examined endothelial function (nitric-oxide mediated) in 29 men with diet-treated non-insulin-dependent (Type 2) diabetes mellitus (NIDDM) and 18 male age-matched controls. Forearm blood flow was measured by venous occlusive plethysmography during
Publikováno v:
Diabetic medicine : a journal of the British Diabetic Association. 13(6)
The frequency of urinary infection was determined using quantitative microbiology in 172 insulin-dependent diabetic patients repeatedly being tested for microalbuminuria over 18 months on at least six occasions. The point prevalence of urinary infect