Zobrazeno 1 - 7
of 7
pro vyhledávání: '"S F, Fidler"'
Publikováno v:
Agents and Actions. 39:136-138
Hyperoxia (95% oxygen) in rats caused an increase in lung weight and an accumulation of fluid in the thorax. The mean lung wet weight of air-breathing controls at 60 h was 1.2 +/- 0.01 g, and that of vehicle-treated, oxygen-exposed animals was 2.45 +
Autor:
J E, Chin, C A, Hatfield, G E, Winterrowd, R F, Krzesicki, K L, Shull, S F, Fidler, K P, Kolbasa, J R, Brashler, R L, Griffin, W E, Fleming, J M, Justen, L S, Banitt, G L, Bundy, I M, Richards
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 290(1)
The anti-inflammatory properties of a novel pyrrolopyrimidine, PNU-142731A, in a murine model of antigen-induced eosinophilic lung inflammation are described. PNU-142731A, when given orally, demonstrated a dose-related inhibition of eosinophil- and l
Autor:
I. M. Richards, S. F. Fidler, F. P. Bell, C. A. Hatfield, R. L. Griffin, Jia En Chin, J. L. Mobley, K. P. Kolbasa, J. R. Brashler, G. E. Winterrowd, Kathy L. Shull
Publikováno v:
The American journal of physiology. 273(3 Pt 1)
The role of intercellular adhesion molecule-1 (ICAM-1) in murine lung inflammation was examined in vivo. Ovalbumin (Ova)-sensitized and -challenged ICAM-1-deficient (KO) mice had decreased accumulation of leukocytes in the bronchoalveolar lavage flui
Autor:
Jia En Chin, G. E. Winterrowd, R. L. Griffin, R. F. Krzesicki, J. R. Brashler, S. F. Fidler, K. P. Kolbasa, S. L. Vonderfecht, C. A. Hatfield, L. M. Sly, I. M. Richards, N. D. Staite
Publikováno v:
The American journal of physiology. 272(2 Pt 1)
The involvement of the alpha4-integrin very late activation antigen 4 and vascular cell adhesion molecule-1 (VCAM-1) in leukocyte trafficking into the airways of ovalbumin (OA)-sensitized and OA-challenged mice was investigated using in vivo administ
Publikováno v:
Agents and actions. 37(3-4)
Antigen inhalation in sensitized dogs, guinea pigs and rats resulted in a marked, late-phase, eosinophil-rich, influx of inflammatory cells into the bronchial lumen. Attempts to demonstrate an associated late-phase bronchoconstriction were disappoint
Publikováno v:
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 22(4)
Publikováno v:
Laboratory animal science. 29(2)
A 30-gauge cannula was used to perfuse fixative through the fragile heart of a newborn opossum. The cannula was gently maneuvered into the heart and held in place with a specially designed manipulator. The flow rate of the fixative was regulated with