Zobrazeno 1 - 6
of 6
pro vyhledávání: '"S F, Averin"'
Autor:
V S, Khlebnikov, I R, Golovlev, V E, Zhemchugov, A M, Chugunov, S F, Averin, S S, Afanas'ev, I Ia, Kalachev, S Iu, Pchelintsev, N N, Kislichkin
Publikováno v:
Zhurnal mikrobiologii, epidemiologii i immunobiologii. (3)
The protective properties of the preparation of F. tularensis outer membranes (OM), obtained from F. tularensis vaccine strain 15, were studied in experiments on hamadryas baboons challenged subcutaneously with F. tularensis virulent strain Schu (non
Autor:
V S, Khlebnikov, I R, Golovlev, A M, Chugunov, V E, Zhemchugov, S F, Averin, S S, Afanas'ev, S Iu, Pshirkov, S I, Konovalov, A V, Stepanov
Publikováno v:
Zhurnal mikrobiologii, epidemiologii i immunobiologii. (1)
Subcutaneous immunization, made in a single injection, with outer membrane preparations obtained from F.tularensis vaccine strain 15 and virulent strain A'Cole results in intensive immunity to tularemia in guinea pigs, ensuring the protection of 60-1
Autor:
V S, Khlebnikov, I R, Golovlev, N V, Tokhtamysheva, S F, Averin, D P, Kulevatskiĭ, G K, Grechko, A A, Averina, S S, Vetchinin
Publikováno v:
Zhurnal mikrobiologii, epidemiologii i immunobiologii. (1)
F. tularensis lipopolysaccharide (LPS) was studied with the use of monoclonal antibodies (McAb) having protective properties. The binding site of these McAb (IgG2a) is localized on the O-chain of LPS. In contrast to LPS isolated from vaccine strain 1
Autor:
V S, Khlebnikov, D P, Kulevatskiĭ, I R, Golovlev, S F, Averin, V E, Zhemchugov, A M, Chugunov, S S, Afanas'ev
Publikováno v:
Zhurnal mikrobiologii, epidemiologii i immunobiologii. (3)
LPS-protein complex containing proteins of 15 kD, 17 kD and 19 kD was isolated from F. tularensis outer membrane by solving with sodium deoxycholate with the subsequent gel filtration on Sephacryl S-200. Protein of 17 kD constituted the main protein
Autor:
V S, Khlebnikov, S S, Vetchinin, G K, Grechko, A A, Averina, I R, Golovlev, S F, Averin, V E, Zhemchugov, S I, Konovalov, G A, Anisimov, S S, Afanas'ev
Publikováno v:
Zhurnal mikrobiologii, epidemiologii i immunobiologii. (9-10)
The preventive activity of five monoclonal antibodies (McAb) in experimental tularemia was evaluated. McAb produced by hybridoma FB11-k (IgG2a), specific to F. tularensis lipopolysaccharide, prevented the death of mice and guinea pigs infected with F
Autor:
V S, Khlebnikov, I R, Golovlev, D P, Kulevatskiĭ, S F, Averin, S Iu, Pshirkov, N V, Tokhtamysheva, V E, Zhemchugov, L A, Safonova, V N, Gerasimov, A M, Chugunov
Publikováno v:
Molekuliarnaia genetika, mikrobiologiia i virusologiia. (7)
The outer membranes of Francisella tularensis were studied. The membranes were identified morphologically, immunologically and biochemically. They contained 12-20% of protein, 15-30% of carbohydrates, up to 40% of lipids. The main integral proteins o