Zobrazeno 1 - 2
of 2
pro vyhledávání: '"S Erandika Senevirathne"'
Publikováno v:
Curr Opin Immunol
Myeloid cells (macrophages, monocytes, dendritic cells, and granulocytes) survey the body for signs of infection and tissue damage and regulate tissue homeostasis, organogenesis, and immunity. They express receptors that initiate the inflammatory res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::356e5544f396e229cdcd7f87930f4729
https://doi.org/10.1016/j.coi.2021.09.004
https://doi.org/10.1016/j.coi.2021.09.004
Autor:
Ben F. Brian, Monica L. Sauer, Joseph T. Greene, S. Erandika Senevirathne, Anders J. Lindstedt, Olivia L. Funk, Brian L. Ruis, Luis A. Ramirez, Jennifer L. Auger, Whitney L. Swanson, Myra G. Nunez, Branden S. Moriarity, Clifford A. Lowell, Bryce A. Binstadt, Tanya S. Freedman
Publikováno v:
Science advances, vol 8, iss 16
Here, we report that the LynB splice variant of the Src-family kinase Lyn exerts a dominant immunosuppressive function in vivo, whereas the LynA isoform is uniquely required to restrain autoimmunity in female mice. We used CRISPR-Cas9 gene editing to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d79a31ea6ce138ddaa264f5f1d06771d
https://escholarship.org/uc/item/4pr231mw
https://escholarship.org/uc/item/4pr231mw
