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pro vyhledávání: '"S El Kadi"'
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
BackgroundR/S enantiomers of 11-hydroxyeicosatertraenoic acid (11-HETE) are formed from arachidonic acid by enzymatic and non-enzymatic pathways. 11-HETE is predominately formed by the cytochrome P450 1B1 (CYP1B1). The role of CYP1B1 in the developme
Externí odkaz:
https://doaj.org/article/a6ef4309c04a4b79a3dc7c0bb928c2f1
Autor:
Zaid H. Maayah, Shingo Takahara, Abrar S. Alam, Mourad Ferdaoussi, Gopinath Sutendra, Ayman O. S. El-Kadi, John R. Mackey, Edith Pituskin, D. Ian Paterson, Jason R. B. Dyck
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-13 (2020)
Abstract Background The survival rates of women with breast cancer have improved significantly over the last four decades due to advances in breast cancer early diagnosis and therapy. However, breast cancer survivors have an increased risk of cardiov
Externí odkaz:
https://doaj.org/article/85cb936846a4464bbf833e47748de3a0
Publikováno v:
Annual Review of Pharmacology and Toxicology. 63:341-358
Arsenic is a naturally occurring hazardous element that is environmentally ubiquitous in various chemical forms. Upon exposure, the human body initiates an elimination pathway of progressive methylation into relatively less bioreactive and more easil
Autor:
Sherif M. Shoieb, Ahmad H. Alammari, Jody Levasseur, Heidi Silver, Jason R. B. Dyck, Ayman O. S. El-Kadi
Publikováno v:
Journal of Cardiovascular Pharmacology. 79:833-845
Cytochrome P450 1B1 (CYP1B1) is known to be involved in the pathogenesis of several cardiovascular diseases, including cardiac hypertrophy and heart failure, through the formation of cardiotoxic metabolites named as mid-chain hydroxyeicosatetraenoic
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Publikováno v:
Journal of Agricultural Chemistry and Biotechnology. 12:211-218
Publikováno v:
Drug metabolism reviews.
The incidence of heart failure (HF) is generally preceded by cardiac hypertrophy (CH), which is the enlargement of cardiac myocytes in response to stress. During CH, the metabolism of arachidonic acid (AA), which is present in the cell membrane phosp
Publikováno v:
Journal of Biochemical and Molecular Toxicology. 37
The cytochrome P450 1 A (CYP1A) subfamily enzymes are involved in the metabolic activation of several xenobiotics to toxic metabolites and reactive intermediates, resulting ultimately in carcinogenesis. Mercury and halogenated aromatic hydrocarbons (
Publikováno v:
Drug metabolism reviews. 54(2)
Understanding lipid metabolism is a critical key to understanding the pathogenesis of Diabetes Mellitus (DM). It is known that 60-90% of DM patients are obese or used to be obese. The incidence of obesity is rising owing to the modern sedentary lifes
Autor:
T Meijers, S El Kadi, Wilco Tanis, W L Blok, Steven A. J. Chamuleau, T I G van der Spoel, Robert Riezebos, D M F van den Buijs, Sebastiaan C.A.M. Bekkers, Ali R. Wahadat, Martijn Gilbers, Otto Kamp, J.W. Roos-Hesselink, J.P. van Melle
Publikováno v:
Netherlands Heart Hournal, 28(10), 526-536. Bohn, Stafleu, Van Loghum
Netherlands Heart Journal, 28(10), 526-536. Bohn Stafleu van Loghum
Netherlands Heart Journal
El Kadi, S, van den Buijs, D M F, Meijers, T, Gilbers, M D, Bekkers, S C A M, van Melle, J P, Riezebos, R K, Blok, W L, Tanis, W, Wahadat, A R, Roos-Hesselink, J W, van der Spoel, T I G, Chamuleau, S A J, Kamp, O & EURO ENDO Investigators group 2020, ' Infective endocarditis in the Netherlands : current epidemiological profile and mortality: An analysis based on partial ESC EORP collected data ', Netherlands Heart Journal, vol. 28, no. 10, pp. 526-536 . https://doi.org/10.1007/s12471-020-01431-z
Netherlands Heart Journal, 28(10), 526-536. Bohn Stafleu van Loghum
Netherlands Heart Journal
El Kadi, S, van den Buijs, D M F, Meijers, T, Gilbers, M D, Bekkers, S C A M, van Melle, J P, Riezebos, R K, Blok, W L, Tanis, W, Wahadat, A R, Roos-Hesselink, J W, van der Spoel, T I G, Chamuleau, S A J, Kamp, O & EURO ENDO Investigators group 2020, ' Infective endocarditis in the Netherlands : current epidemiological profile and mortality: An analysis based on partial ESC EORP collected data ', Netherlands Heart Journal, vol. 28, no. 10, pp. 526-536 . https://doi.org/10.1007/s12471-020-01431-z
Introduction Infective endocarditis (IE) is associated with a high in-hospital and long term mortality. Although progress has been made in diagnostic approach and management of IE, morbidity and mortality of IE remain high. In the latest European gui