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of 765
pro vyhledávání: '"S Efendić"'
Publikováno v:
Scandinavian cardiovascular journal : SCJ. 42(1)
Determine if pre-emptive daily insulin glargine surpasses regular insulin when needed for glycaemic control after cardiac surgery.Prospective, randomized study of 43 patients (scheduled for coronary artery bypass grafting) with preoperatively diagnos
Autor:
S. Efendić, Å Sjöholm
Publikováno v:
Experimental and clinical endocrinologydiabetes : official journal, German Society of Endocrinology [and] German Diabetes Association. 109
Type 2 diabetes mellitus, a major health care problem in the Western world, is a disease typified by a relative deficiency of insulin, leading to vast derangements in glucose and lipid homeostasis with disastrous vascular complications. Despite immen
Autor:
I B, Efanova, S V, Zaitsev, B, Zhivotovsky, M, Köhler, S, Efendić, S, Orrenius, P O, Berggren
Publikováno v:
The Journal of biological chemistry. 273(50)
High concentrations of glucose are considered to be toxic for the pancreatic beta-cell. However, the mechanisms underlying beta-cell dysfunction and resulting cell death are not fully characterized. In the present study we have demonstrated that incu
Publikováno v:
Diabetes. 45(7)
The GK rat is a spontaneous model of NIDDM. The insulin response to 16.7 mmol/l glucose was markedly impaired in both isolated perfused pancreas and isolated islets from GK rats compared with control Wistar rats. Depolarization with 30 mmol/l KCl in
Publikováno v:
Acta paediatrica Scandinavica. 79(4)
Recently we reported that insulin resistance and glucose induced insulin release are inversely correlated to age in young healthy siblings of diabetic patients. To confirm this pattern of change with age, the subjects were reexamined after two years.
Akademický článek
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Publikováno v:
Hormone and Metabolic Research. 11:415-423
Publikováno v:
Scandinavian Journal of Clinical and Laboratory Investigation. 40:749-753
The aim of the study was to elucidate whether disturbances of sympathetic and parasympathetic control of cardiac functions appear in short-term diabetics. For this purpose, cardiovascular reflexes [resting heart rate (HR), respiratory sinus arrhythmi
Previous exposure to glucose enhances somatostatin secretion from the isolated perfused rat pancreas
Publikováno v:
Diabetologia. 20:495-500
Previous exposure to glucose enhances insulin and depresses glucagon secretion by the pancreas. We have investigated whether secretion of somatostatin is also influenced by a glucose priming effect. In perfused rat pancreas from 36 h fasted rats a 5