Zobrazeno 1 - 10
of 47
pro vyhledávání: '"S E Shackney"'
Publikováno v:
Postgraduate medicine.
Breast cancer is a classic hormone-dependent malignant disease that is influenced by estrogen. However, the molecular links between estrogen and cell proliferation in healthy and malignant breast tissue are complex and as yet not well understood. The
Publikováno v:
Cytometry. 42(6)
Laser scanning cytometry (LSC) is a relatively new slide-based technology developed for commercial use by CompuCyte (Cambridge, MA) for performing multiple fluorescence measurements on individual cells. Because techniques developed for performing fou
Autor:
C A, Smith, A A, Pollice, L P, Gu, K A, Brown, S G, Singh, L E, Janocko, R, Johnson, T, Julian, D, Hyams, N, Wolmark, L, Sweeney, J F, Silverman, S E, Shackney
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 6(1)
Human solid tumors develop multiple genetic abnormalities that accumulate progressively in individual cells during the course of tumor evolution. We sought to determine whether there are specific sequences of occurrence of these progressive evolution
Autor:
S E, Shackney, T V, Shankey
Publikováno v:
Cytometry. 35(2)
Some cell cycle models assume that cells are normally in a quiescent state until they are stimulated to enter the cell cycle and proceed through an S phase of fixed duration. Other models assume that cells normally cycle rapidly until they undergo gr
Autor:
S E, Shackney, A A, Pollice, C A, Smith, L E, Janocko, L, Sweeney, K A, Brown, S G, Singh, L, Gu, R, Yakulis, J F, Lucke
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 4(4)
Multiparameter flow cytometry studies were performed on cells from the primary tumors of 94 patients with breast cancer. Correlated cellular measurements of cell DNA content, Her-2/neu, epidermal growth factor receptor (EGFR), and p21ras levels were
Autor:
S E, Shackney, T V, Shankey
Publikováno v:
Cytometry. 29(1)
Human solid tumors develop multiple genetic evolutionary abnormalities as they evolve. Studies that have focused primarily on early colorectal cancer have suggested that genetic instability is a prominent feature of preinvasive disease. At least two
Autor:
S E, Shackney
Publikováno v:
Cytometry. 25(1)
Autor:
S E, Shackney, A A, Pollice, C A, Smith, L, Alston, S G, Singh, L E, Janocko, K A, Brown, S, Petruolo, D W, Groft, R, Yakulis, R J, Hartsock
Publikováno v:
The cancer journal from Scientific American. 2(2)
Human solid tumors undergo multiple genetic evolutionary changes as they evolve from the normal state to advanced stages of malignancy. This study characterizes the degree of advancement of primary human breast cancers in their genetic evolutionary p
Publikováno v:
Archives of pathologylaboratory medicine. 114(9)
Clinicopathologic characteristics were evaluated in 20 cases of cystosarcoma phyllodes in relation to clinical outcome. Flow cytometric DNA studies were carried out in 15 of these 20 cases. Stromal overgrowth and an infiltrating tumor border emerged
Publikováno v:
Cancer. 66(3)
A drug schedule has been devised based on a strategy of G2 blockade followed by prolonged infusion of tubulin-binding agents. The regimen consists of doxorubicin 32 mg/m2 i.v. and cyclophosphamide 320 mg/m2 i.v. on day 1 followed by vinblastine (0.3