Zobrazeno 1 - 6
of 6
pro vyhledávání: '"S E Plevy"'
Autor:
D. Shealy, G. D'Haens, S. R. Targan, C. Wagner, K. Geboes, Freddy Cornillie, S. E. Plevy, G. Van Assche, Paul Rutgeerts, Thomas F. Schaible, Jan Ceuppens
Publikováno v:
Alimentary Pharmacology & Therapeutics. 15:463-473
Background: Anti-TNFα therapy with infliximab is effective for Crohn’s disease. Infliximab neutralizes the biological activities of TNFα, a cytokine involved in host-defence against certain infections. Aim: To evaluate the effects of infliximab o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b5aea8adb2fb56cfa90976cec5f84a1
https://doi.org/10.1046/j.1365-2036.2001.00956.x
https://doi.org/10.1046/j.1365-2036.2001.00956.x
Publikováno v:
The Journal of Immunology. 159:6276-6282
Recent clinical studies of Crohn's disease patients demonstrated dramatic clinical responses following one i.v. infusion of a chimeric mAb to TNF-alpha (cA2). To assess the role of TNF-alpha in mucosal cytokine regulation, the effects of TNF-alpha on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21971026521fa1c23f2eb7631af72f65
https://doi.org/10.4049/jimmunol.159.12.6276
https://doi.org/10.4049/jimmunol.159.12.6276
Autor:
F, Cornillie, D, Shealy, G, D'Haens, K, Geboes, G, Van Assche, J, Ceuppens, C, Wagner, T, Schaible, S E, Plevy, S R, Targan, P, Rutgeerts
Publikováno v:
Alimentary pharmacologytherapeutics. 15(4)
Anti-TNFalpha therapy with infliximab is effective for Crohn's disease. Infliximab neutralizes the biological activities of TNFalpha, a cytokine involved in host-defence against certain infections.To evaluate the effects of infliximab on the gut and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9eafc3d95ca8072935e9b6295862b9a8
https://pubmed.ncbi.nlm.nih.gov/11736736
https://pubmed.ncbi.nlm.nih.gov/11736736
Publikováno v:
The Journal of biological chemistry. 276(21)
Interleukin (IL)-12 is a heterodimeric cytokine produced by macrophages in response to intracellular pathogens and provides an obligatory signal for the differentiation of T-helper-1 cells. We previously reported an analysis of the IL-12 p40 promoter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fbf089f07c3e47a33208b68db420d60d
https://pubmed.ncbi.nlm.nih.gov/11279072
https://pubmed.ncbi.nlm.nih.gov/11279072
Autor:
Jerome I. Rotter, Dolly B. Tyan, Nathan Fischel-Ghodsian, Kent D. Taylor, Colleen McElree, Huiying Yang, Stephan R. Targan, S E Plevy
Publikováno v:
Gut. 44(4)
BACKGROUNDThere is evidence for genetic susceptibility to Crohn’s disease, and a tentative association with tumour necrosis factor (TNF) and HLA class II alleles.AIMSTo examine the potential of genetic linkage between Crohn’s disease and the MHC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32096a1a76e919ff6d57fc42cc8dc84f
https://pubmed.ncbi.nlm.nih.gov/10075959
https://pubmed.ncbi.nlm.nih.gov/10075959
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 159(12)
Recent clinical studies of Crohn's disease patients demonstrated dramatic clinical responses following one i.v. infusion of a chimeric mAb to TNF-alpha (cA2). To assess the role of TNF-alpha in mucosal cytokine regulation, the effects of TNF-alpha on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3da032bdf54e54eedb6c8f1c59aaeba1
https://pubmed.ncbi.nlm.nih.gov/9550432
https://pubmed.ncbi.nlm.nih.gov/9550432